Expression of P‐selectin and intercellular adhesion molecule‐1 in human brain after focal infarction or cardiac arrest

Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

1995 • 3,456 citations

Intravenous Thrombolysis With Recombinant Tissue Plasminogen Activator for Acute Hemispheric Stroke

1995 • 2,209 citations

Inflammation and Stroke: Putative Role for Cytokines, Adhesion Molecules and iNOS in Brain Response to Ischemia

2000 • 653 citations

Effects of Tissue Plasminogen Activator for Acute Ischemic Stroke at One Year

1999 • 633 citations

An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration.

1994 • 597 citations

Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke.

1996 • 521 citations

P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion.

1994 • 428 citations

Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke

1998 • 414 citations

Selective expression of adhesion molecules on human brain microvascular endothelial cells

1997 • 368 citations

Anti‐ICAM‐1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in the rat

1994 • 360 citations

Anti–Intercellular Adhesion Molecule–1 Antibody Reduces Ischemic Cell Damage After Transient But Not Permanent Middle Cerebral Artery Occlusion in the Wistar Rat

1995 • 346 citations

The biphasic opening of the blood–brain barrier in the cortex and hippocampus after traumatic brain injury in rats

1997 • 317 citations

Neuronal Protection in Stroke by an sLe ^x -Glycosylated Complement Inhibitory Protein

1999 • 313 citations

Intracerebral Inflammation after Human Brain Contusion

1998 • 270 citations

Endothelial ICAM-1 Expression Associated With Inflammatory Cell Response in Human Ischemic Stroke

1996 • 264 citations

Anti‐CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat

1994 • 231 citations

Mice Deficient in Mac-1 (CD11b/CD18) Are Less Susceptible to Cerebral Ischemia/Reperfusion Injury

1999 • 216 citations

Inflammatory Gene Expression in Cerebral Ischemia and Trauma

1997 • 207 citations

The role of inflammation after acute stroke

1998 • 204 citations

Monoclonal antibodies preventing leukocyte activation reduce experimental neurologic injury and enhance efficacy of thrombolytic therapy

1995 • 192 citations

Antibodies against Adhesion Molecules Reduce Apoptosis after Transient Middle Cerebral Artery Occlusion in Rat Brain

1996 • 188 citations

CD18-Mediated Neutrophil Recruitment Contributes to the Pathogenesis of Reperfused but Not Nonreperfused Stroke

1999 • 178 citations

Deficiency of Intercellular Adhesion Molecule 1 Attenuates Microcirculatory Disturbance and Infarction Size in Focal Cerebral Ischemia

1998 • 149 citations

Cerebral Malaria

1997 • 137 citations

Neuronal death in brain infarcts in man

2000 • 131 citations

TWEAK stimulation of astrocytes and the proinflammatory consequences

2000 • 128 citations

Inflammation and acute stroke

1998 • 126 citations

Anti-ICAM-1 Monoclonal Antibody R6.5 (Enlimomab) Promotes Activation of Neutrophils in Whole Blood

1999 • 125 citations

Hu23F2G, an Antibody Recognizing the Leukocyte CD11/CD18 Integrin, Reduces Injury in a Rabbit Model of Transient Focal Cerebral Ischemia

1998 • 119 citations

E-Selectin in Focal Cerebral Ischemia and Reperfusion in the Rat

1996 • 111 citations

Increase in Surface Expression of ICAM-1, VCAM-1 and E-Selectin in Human Cerebromicrovascular Endothelial Cells Subjected to Ischemia-Like Insults

1997 • 110 citations

Dichotomized Efficacy End Points and Global End-Point Analysis Applied to the ECASS Intention-to-Treat Data Set

1998 • 108 citations

Significance of the Inflammatory Response in Brain Ischemia

1996 • 101 citations

Postischemic treatment (2–4 h) with anti-CD11b and anti-CD18 monoclonal antibodies are neuroprotective after transient (2 h) focal cerebral ischemia in the rat

1995 • 99 citations

Increased therapeutic efficacy with rt-PA and anti-CD18 antibody treatment of stroke in the rat

1999 • 92 citations

Soluble intercellular adhesion molecule-1, E-selectin, vascular cell adhesion molecule-1 and von Willebrand factor in stroke

1999 • 88 citations

Soluble Adhesion Molecules in CSF Are Increased in Children With Severe Head Injury

1998 • 77 citations

Neuronal accumulation of poly(ADP‐ribose) after brain ischaemia

1999 • 74 citations

Safety, Pharmacokinetics and Biological Activity of Enlimomab (Anti-ICAM-1 Antibody): An Open-Label, Dose Escalation Study in Patients Hospitalized for Acute Stroke

1998 • 73 citations

Anti-P-selectin antibody attenuates rat brain ischemic injury

1999 • 63 citations

Apoptosis and expression of DNA repair proteins in ischaemic brain injury in man

1998 • 61 citations

Soluble ICAM-1 reduces leukocyte adhesion to vascular endothelium in ischemia-reperfusion injury in mice

1998 • 47 citations

Activation of caspase-3 in permanent and transient brain ischaemia in man

2000 • 45 citations

Reduction of ischemic brain injury by anti-P-selectin monoclonal antibody after permanent middle cerebral artery occlusion in rat

1999 • 39 citations

Humanized anti-L-selectin monoclonal antibody DREC200 therapy in acute thromboembolic stroke

1998 • 36 citations

Expression of cell adhesion molecules by microvascular endothelial cells in the cortical and subcortical regions of the normal human brain: an immunohistochemical analysis

1997 • 34 citations

Development of Bombesin-Like and Histamine-Like Innervation in the Bullfrog <i>(Rana catesbeiana) </i>Central Nervous System

1997 • 16 citations

rtPA in acute ischemic stroke

1997 • 7 citations

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