Tamoxifen and Breast Cancer Incidence Among Women With Inherited Mutations in BRCA1 and BRCA2

Base-Calling of Automated Sequencer Traces UsingPhred. I. Accuracy Assessment

1998 • 6,925 citations

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

1994 • 5,994 citations

Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

1998 • 5,487 citations

Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities

1998 • 5,382 citations

Tamoxifen for early breast cancer: an overview of the randomised trials

1998 • 4,082 citations

Identification of the breast cancer susceptibility gene BRCA2

1995 • 3,581 citations

Consed: A Graphical Tool for Sequence Finishing

1998 • 3,325 citations

Projecting Individualized Probabilities of Developing Breast Cancer for White Females Who Are Being Examined Annually

1989 • 3,239 citations

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

1990 • 2,505 citations

Cancer Risks in BRCA2 Mutation Carriers

1999 • 1,477 citations

A Randomized Clinical Trial Evaluating Tamoxifen in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor–Positive Tumors

1989 • 1,471 citations

PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing

1997 • 946 citations

Breast Cancer after Prophylactic Bilateral Mastectomy in Women with aBRCA1orBRCA2Mutation

2001 • 945 citations

Prevalence of BRCA1 and BRCA2 Gene Mutations in Patients With Early-Onset Breast Cancer

1999 • 866 citations

Weighing the Risks and Benefits of Tamoxifen Treatment for Preventing Breast Cancer

1999 • 676 citations

Breast Cancer Risk After Bilateral Prophylactic Oophorectomy in BRCA1 Mutation Carriers

1999 • 674 citations

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

2001 • 626 citations

Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases

1997 • 580 citations

Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study

2000 • 536 citations

Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1

1998 • 453 citations

Prevalence and Penetrance of BRCA1 and BRCA2 Gene Mutations in Unselected Ashkenazi Jewish Women With Breast Cancer

1999 • 390 citations

Frequency of Breast Cancer Attributable to <EMPH TYPE="ITAL">BRCA1</EMPH> in a Population-Based Series of American Women

1998 • 350 citations

Tumour biological features of BRCA1-induced breast and ovarian cancer

1997 • 346 citations

BRCA1 and BRCA2 Mutation Analysis of 208 Ashkenazi Jewish Women with Ovarian Cancer

2000 • 311 citations

BRCA-associated breast cancer in young women.

1998 • 309 citations

Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1.

1996 • 272 citations

Distinct molecular pathogeneses of early-onset breast cancers in BRCA1 and BRCA2 mutation carriers: a population-based study.

1999 • 229 citations

Frequency ofBRCA1/BRCA2 mutations in a population-based sample of young breast carcinoma cases

2000 • 207 citations

Steroid receptors in hereditary breast carcinomas associated with BRCA1 or BRCA2 mutations or unknown susceptibility genes

1998 • 185 citations

Survival in Hereditary Breast Cancer Associated With Germline Mutations of BRCA2

1999 • 183 citations

Influence of BRCA1 mutations on nuclear grade and estrogen receptor status of breast carcinoma in Ashkenazi Jewish women

1997 • 177 citations

BRCA1-related breast cancer in Austrian breast and ovarian cancer families: SpecificBRCA1 mutations and pathological characteristics

1998 • 98 citations

Breast Carcinomas Arising in Carriers of Mutations in BRCA1 or BRCA2: Are They Prognostically Different?

1999 • 95 citations

BRCA1 1675delA and 1135insA Account for One Third of Norwegian Familial Breast-Ovarian Cancer and Are Associated with Later Disease Onset than Less Frequent Mutations

1999 • 31 citations

SeqHelp: A Program to Analyze Molecular Sequences Utilizing Common Computational Resources

1998 • 28 citations

Incidence of BRCA1/2 germ line alterations in a high risk cohort participating in a phase II chemoprevention trial

2000 • 6 citations