A catalogue of imprinted genes and parent-of-origin effects in humans and animals

Parental imprinting of the mouse insulin-like growth factor II gene

1991 • 1,773 citations

Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

1997 • 1,636 citations

A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

1991 • 1,469 citations

Parental imprinting of the mouse H19 gene

1991 • 1,192 citations

The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

1991 • 904 citations

Relaxation of imprinted genes in human cancer

1993 • 792 citations

Disruption of imprinting caused by deletion of the H19 gene region in mice

1995 • 765 citations

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

1995 • 749 citations

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

1993 • 710 citations

Evidence from Turner's syndrome of an imprinted X-linked locus affecting cognitive function

1997 • 670 citations

Autism or atypical autism in maternally but not paternally derived proximal 15q duplication.

1997 • 639 citations

Essential role of Mash-2 in extraembryonic development

1994 • 612 citations

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal

1993 • 602 citations

Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons

1997 • 495 citations

A genetic study of type 2 neurofibromatosis in the United Kingdom. I. Prevalence, mutation rate, fitness, and confirmation of maternal transmission effect on severity.

1992 • 452 citations

The maternal effects on growth and conformation in shire horse-shetland pony crosses

1938 • 451 citations

Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region

1994 • 430 citations

Uniparental disomy in humans: development of an imprinting map and its implications for prenatal diagnosis

1995 • 410 citations

Monoallelic expression of the human H19 gene

1992 • 409 citations

Association between atopy and variants of the β subunit of the high–affinity immunoglobulin E receptor

1994 • 406 citations

Genomic imprinting of Mash2, a mouse gene required for trophoblast development

1995 • 366 citations

Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements

1997 • 354 citations

Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect.

1995 • 347 citations

Preferential expression of the maternally derived X chromosome in the mouse yolk sac

1977 • 328 citations

Imprinting in Albright's hereditary osteodystrophy.

1993 • 306 citations

GENOMIC IMPRINTING IN HEREDITARY GLOMUS TUMOURS: EVIDENCE FOR NEW GENETIC THEORY

1989 • 305 citations

Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15.

1996 • 302 citations

Uniparental disomy 7 in Silver—Russell syndrome and primordial growth retardation

1995 • 299 citations

HUMAN TYPE 1 DIABETES AND THE INSULIN GENE: Principles of Mapping Polygenes

1996 • 291 citations

IGF2 is parentally imprinted during human embryogenesis and in the Beckwith–Wiedemann syndrome

1993 • 290 citations

Genomic imprinting of p57KIP2, a cyclin–dependent kinase inhibitor, in mouse

1995 • 288 citations

Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S.cerevisiae telomeres

1997 • 277 citations

Imprint switching on human chromosome 15 may involve alternative transcripts of the SNRPN gene

1996 • 257 citations

Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein

1996 • 252 citations

The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region

1997 • 247 citations

Maternal imprinting of the mouse Snrpn gene and conserved linkage homology with the human Prader–Willi syndrome region

1992 • 243 citations

Identification of a novel paternally expressed gene in the Prader - Willi syndrome region

1994 • 243 citations

The insulin–like growth factor type–2 receptor gene is imprinted in the mouse but not in humans

1993 • 238 citations

The Necdin Gene is Deleted in Prader-Willi Syndrome and is Imprinted in Human and Mouse

1997 • 230 citations

Imprinting and X chromosome counting mechanisms determine Xist expression in early mouse development

1994 • 229 citations

Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

1993 • 228 citations

Parent-of-origin effects in multiple endocrine neoplasia type 2B.

1994 • 224 citations

Molecular definition of the chromosome 7 deletion in Williams syndrome and parent-of-origin effects on growth.

1996 • 223 citations

Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma

1989 • 221 citations

Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method

1994 • 219 citations

Allele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprinting

1994 • 219 citations

Patterns of maternal transmission in bipolar affective disorder.

1995 • 216 citations

A DNA methylation imprint, determined by the sex of the parent, distinguishes the angelman and Prader-Willi syndromes

1992 • 212 citations

Meiotic origin of trisomy in confined placental mosaicism is correlated with presence of fetal uniparental disomy, high levels of trisomy in trophoblast, and increased risk of fetal intrauterine growth restriction.

1997 • 205 citations

Paternal origin of new mutations in Von Recklinghausen neurofibromatosis

1990 • 204 citations

Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS–M

1996 • 195 citations

The complex pathology of trinucleotide repeats

1997 • 191 citations

Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele

1997 • 189 citations

Relationship between homozygosity at the dopamine D3 receptor gene and schizophrenia

1994 • 179 citations

The enhancer of position-effect variegation of Drosophila, E(var)3-93D, codes for a chromatin protein containing a conserved domain common to several transcriptional regulators.

1993 • 178 citations

Minimal definition of the imprinting center and fixation of chromosome 15q11-q13 epigenotype by imprinting mutations.

1996 • 176 citations

Parental imprinting of the human H19 gene

1992 • 176 citations

Parental origin effects in mice

1986 • 175 citations

Mosaic and polymorphic imprinting of the WT1 gene in humans

1994 • 172 citations

IDDM2-VNTR-encoded Susceptibility to Type 1 Diabetes: Dominant Protection and Parental Transmission of Alleles of the Insulin Gene-linked Minisatellite Locus

1996 • 165 citations

The IPL Gene on Chromosome 11p15.5 is Imprinted in Humans and Mice and is Similar to TDAG51, Implicated in Fas Expression and Apoptosis

1997 • 164 citations

Functional imprinting and epigenetic modification of the human SNRPN gene

1993 • 158 citations

Human PEG1/MEST, an Imprinted Gene on Chromosome 7

1997 • 158 citations

Identification of the Meg1 / Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver–Russell syndrome gene

1998 • 155 citations

Genomic imprinting: potential function and mechanisms revealed by the Prader-Willi and Angelman syndromes

1997 • 150 citations

Further evidence for an imprinted gene for neonatal diabetes localised to chromosome 6q22-q23

1996 • 145 citations

Modification of 15q11 — q13 DNA methylation imprints in unique Angelman and Prader — Willi patients

1993 • 142 citations

Production of Androgenetic Zebrafish (Danio rerio)

1996 • 139 citations

Fine mapping of a putatively imprinted gene for familial non-chromaffin paragangliomas to chromosome 11q13.1: evidence for genetic heterogeneity

1995 • 137 citations

Higher risk of seizures in offspring of mothers than of fathers with epilepsy.

1988 • 130 citations

Experiments in Plant Hybridisation

2008 • 123 citations

Parental origin of transcription from the human GNAS1 gene.

1994 • 120 citations

On the parental origin of de novo mutation in man.

1991 • 119 citations

Conservation of a maternal-specific methylation signal at the human IGF2R locus

1995 • 116 citations

Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors

1996 • 115 citations

The Human Homolog of a Mouse-Imprinted Gene, Peg3, Maps to a Zinc Finger Gene-Rich Region of Human Chromosome 19q13.4

1997 • 108 citations

An Imprinted Mouse Transcript Homologous to the Human Imprinted in Prader-Willi Syndrome (IPW) Gene

1997 • 105 citations

Paternal uniparental disomy for chromosome 14: A case report and review

1997 • 104 citations

Concordance by Sex in Sibling Pairs with Schizophrenia is Paternally Inherited

1989 • 104 citations

Parental imprinting of the Mas protooncogene in mouse

1994 • 104 citations

IMPT1, an imprinted gene similar to polyspecific transporter and multi- drug resistance genes

1998 • 101 citations

THE INHERITANCE AND EXPRESSION OF FUSED, A NEW MUTATION IN THE HOUSE MOUSE

1937 • 100 citations

A new imprinted gene cloned by a methylation-sensitive genome scanning method

1993 • 100 citations

Peg5/Neuronatin is an imprinted gene located on sub-distal chromosome 2 in the mouse

1997 • 98 citations

Imprinting of mouse Kvlqt1 is developmentally regulated

1998 • 98 citations

Genetic and Functional Analysis of neuronatin in Mice with Maternal or Paternal Duplication of Distal Chr 2

1997 • 98 citations

Monoallelic Expression of HumanPEG1/MESTIs Paralleled by Parent-Specific Methylation in Fetuses

1997 • 96 citations

Uniparental disomy of the entire X chromosome in a female with Duchenne muscular dystrophy.

1997 • 96 citations

Screening for imprinted genes by allelic message display: Identification of a paternally expressed gene Impact on mouse chromosome 18

1997 • 93 citations

Growth effects of uniparental disomies and the conflict theory of genomic imprinting

1997 • 93 citations

Imprinting and Anticipation

1994 • 93 citations

Maternal Uniparental Disomy of Chromosome 1 with Reduction to Homozygosity of the LAMB3 Locus in a Patient with Herlitz Junctional Epidermolysis Bullosa

1997 • 89 citations

Fine mapping of an imprinted gene for familial nonchromaffin paragangliomas, on chromosome 11q23.

1997 • 88 citations

Prenatal and postnatal growth failure associated with maternal heterodisomy for chromosome 7.

1995 • 86 citations

Isodisomy of chromosome 6 in a newborn with methylmalonic acidemia and agenesis of pancreatic beta cells causing diabetes mellitus.

1994 • 86 citations

Tissue- and Developmental Stage-Specific Imprinting of the Mouse Proinsulin Gene, Ins2

1995 • 84 citations

Evidence for a Genomic Imprinting Sex Determination Mechanism in Nasonia vitripennis (Hymenoptera; Chalcidoidea)

1998 • 83 citations

Allelic Expression at Enzyme Loci in an Intertribal Hybrid Sunfish

1973 • 82 citations

Differences in risk of Crohn's disease in offspring of mothers and fathers with inflammatory bowel disease.

1997 • 82 citations

Evidence for Uniparental, Paternal Expression of the Human GABAA Receptor Subunit Genes, Using Microcell-Mediated Chromosome Transfer

1997 • 81 citations

Genomic imprinting of a human apoptosis gene homologue, TSSC3.

1998 • 79 citations

The Human Achaete-Scute Homologue 2 (ASCL2, HASH2) Maps to Chromosome 11p15.5, Close to IGF2 and is Expressed in Extravillus Trophoblasts

1997 • 79 citations

The genetics of retinoblastoma, revisited.

1994 • 78 citations

Genomic imprinting of the human serotonin-receptor (HTR2) gene involved in development of retinoblastoma.

1996 • 76 citations

Allelic inhibition at the autosomally inherited gene locus for liver alcohol dehydrogenase in chicken-quail hybrids

1968 • 74 citations

Equus: The Horse in the Roman World

1990 • 72 citations

Paternal X-chromosome inactivation in human trophoblastic cells

1997 • 72 citations

Gtl2 lacZ , an insertional mutation on mouse Chromosome 12 with parental origin-dependent phenotype

1996 • 71 citations

Confined placental mosaicism and intrauterine fetal development

1994 • 71 citations

FERTILITY AND SIZE INHERITANCE IN A PEROMYSCUS SPECIES CROSS

1965 • 70 citations

Maternal-Specific Methylation of the HumanIGF2RGene Is Not Accompanied by Allele-Specific Transcription

1996 • 70 citations

Preferential inhibition of allelic isozyme synthesis in an interspecific sunfish hybrid

1972 • 69 citations

Biological functions and receptor binding activities of equine chorionic gonadotrophins

1981 • 69 citations

Divergently Transcribed Overlapping Genes Expressed in Liver and Kidney and Located in the 11p15.5 Imprinted Domain

1998 • 68 citations

Possible role of imprinting in the Turner phenotype.

1994 • 68 citations

Uniparental isodisomy 6 associated with deficiency of the fourth component of complement.

1990 • 68 citations

Sex of parent transmission effect in Tourette's syndrome

1997 • 62 citations

Preferential amplification of the paternal allele of the N–myc gene in human neuroblastomas

1993 • 62 citations

Psoriasis vulgaris, fetal growth, and genomic imprinting

1992 • 58 citations

Transcriptional map of 170-kb region at chromosome 11p15.5: Identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples

1998 • 57 citations

Parent-of-origin effect in transmission of bipolar disorder

1996 • 57 citations

Short-limb dwarfism and hypertrophic cardiomyopathy in a patient with paternal isodisomy 14: 45,XY,idic(14)(p11)

1996 • 57 citations

Genetic anticipation and imprinting in bipolar I illness

1997 • 56 citations

Parental origin of germ-line and somatic mutations in the retinoblastoma gene

1994 • 55 citations

Clinical evidence of genomic imprinting in Tourette's syndrome

1995 • 55 citations

Maternal Uniparental Isodisomy of Human Chromosome 14 Associated with a Paternal t(13q14q) and Precocious Puberty

1996 • 55 citations

Glomerular-Specific Imprinting of the Mouse Gsα Gene: How Does This Relate to Hormone Resistance in Albright Hereditary Osteodystrophy?

1996 • 55 citations

Current Directions in Insulin-Like Growth Factor Research

1993 • 53 citations

Gene imprinting and major histocompatibility complex class I antigen expression in the rat placenta.

1990 • 53 citations

Complete paternal isodisomy for chromosome 8 unmasked by lipoprotein lipase deficiency.

1996 • 53 citations

Familial paragangliomas: Linkage to chromosome 11q23 and clinical implications

1997 • 52 citations

Parental origin of de novo constitutional deletions of chromosomal band 11p13.

1990 • 51 citations

Human p57KIP2 defines a new imprinted domain on chromosome 11p but is not a tumour suppressor gene in Wilms tumour

1997 • 51 citations

Parental sex effect in spina bifida: A role for genomic imprinting?

1992 • 49 citations

Characterization of the C3 YAC Contig from Proximal Mouse Chromosome 17 and Analysis of Allelic Expression of Genes Flanking the Imprinted Igf2r Gene

1997 • 46 citations

Cys 618 Arg mutation in the RET proto-oncogene associated with familial medullary thyroid carcinoma and maternally transmitted Hirschsprung's disease suggesting a role for imprinting

1997 • 45 citations

Uniparental maternal disomy 6 in a renal transplant patient

1996 • 44 citations

Inherited non-autosomal effects on body fat in F 2 mice derived from an AKR/J × SWR/J cross

1997 • 44 citations

Progressive diaphyseal dysplasia: A three-generation family with markedly variable expressivity

1997 • 43 citations

Anticipation and Imprinting in Schizophrenia

1997 • 43 citations

Absence of Imprinting in U2AFBPL, a Human Homologue of the Imprinted Mouse GeneU2afbp-rs

1996 • 42 citations

Paternal expression of WT1 in human fibroblasts and lymphocytes

1997 • 41 citations

Transitional hemizygosity of the maternally derived allele at the 6PGD locus during early development of the Cyprinid fish Rutilus rutilus

1970 • 41 citations

Parent‐of‐origin specific effects on the methylation of a transgene in the zebrafish, Danio rerio

1995 • 40 citations

PARENTAL CONTROL OF POSITION-EFFECT VARIEGATION: I. PARENTAL HETEROCHROMATIN AND EXPRESSION OF THE WHITE LOCUS IN COMPOUND-X DROSOPHILA MELANOGASTER

1959 • 39 citations

The human/mouse imprinted genesIGF2, H19, SNRPN andZNF127 map to two conserved autosomal clusters in a marsupial

1996 • 39 citations

Clinical evidence for genomic imprinting in bipolar I disorder

1995 • 38 citations

The mouse Necdin gene is expressed from the paternal allele only and lies in the 7C region of the mouse chromosome 7, a region of conserved synteny to the human Prader-Willi syndrome region.

1997 • 38 citations

Transient neonatal diabetes mellitus in a child with invdup(6)(q22q23) of paternal origin.

1998 • 37 citations

Paternal Imprinting of Mouse Serotonin Receptor 2A GeneHtr2in Embryonic Eye: A Conserved Imprinting Regulation on theRB/RbLocus

1998 • 36 citations

Exclusively paternal X chromosomes in a girl with short stature

1993 • 34 citations

Deletion 4q21/4q22 syndrome: Two patients with de novo 4q21.3q23 and 4q13.2q23 deletions

1997 • 33 citations

Pulmonary atresia associated with maternal 22q11.2 deletion: possible parent of origin effect in the conotruncal anomaly face syndrome.

1994 • 30 citations

Imprinting of IGF2, insulin‐dependent diabetes, immune function, and apoptosis: A hypothesis

1995 • 29 citations

Multigenic and imprinting control of ovarian granulosa cell tumorigenesis in mice.

1998 • 29 citations

Identification of a novel paternally expressed transcript adjacent to snRPN in the Prader-Willi syndrome critical region.

1996 • 26 citations

Genomic imprinting and audiogenic seizures in mice.

1997 • 24 citations

Transitory hemizygosity of paternally derived alleles in hybrid trout embryos

1976 • 24 citations

Nondisjunction rates and abnormal embryonic development in a mouse cross between heterozygotes carrying a (7, 18) robertsonian translocation chromosome.

1995 • 24 citations

Differential Genomic Imprinting of Major Histocompatibility Complex Class I Antigens in the Placenta of the Rat1

1993 • 23 citations

TheMASProto-oncogene Is Imprinted in Human Breast Tissue

1997 • 22 citations

Dystrophin expression in heterozygous mdxl+ mice indicates imprinting of X chromosome inactivation by parent-of-origin-, tissue-, strain- and position-dependent factors

1997 • 22 citations

Physical map around the retinoblastoma gene: Possible genomic imprinting suggested by NruI digestion

1991 • 17 citations

Duplication 14(q24.3q31) in a father and daughter: Delineation of a possible imprinted region

1997 • 16 citations

Paternal inheritance of egg traits in mice: a case of genomic imprinting

1989 • 16 citations

TheMASProto-Oncogene Is Not Imprinted in Humans

1996 • 16 citations

On the variable expression of the Brachmann‐de Lange syndrome

1992 • 15 citations

The ovine callipyge locus: a paradigm illustrating the importance of non-Mendelian genetics in livestock.

1996 • 14 citations

Imprinting and loss of ABO antigens in leukemia.

1993 • 13 citations

Earlier onset of melanotroph carcinogenesis in mice with inherited mutant paternal allele of the retinoblastoma gene.

1997 • 13 citations

Experiments in Plant Hybridisation.

1966 • 13 citations

Parental Imprinting of the Genes for IGF-II and Its Receptor

1994 • 9 citations

[Clinical, genetic and molecular studies on autosomal dominant polycystic kidney disease].

1998 • 8 citations

Genomic imprinting of chromatin inDrosophila melanogaster

1996 • 7 citations

The role of genotype, genomic imprinting, and sex hormones in platelet and megakaryocyte production.

1994 • 4 citations

Parental influences on expression of glucose-6-phosphate dehydrogenase,G6pd, in the mouse; a case of imprinting

1990 • 3 citations

Seminal Fluid and the Expression of MHC Class I Antigens in the Placenta of the Rat

1995 • 1 citations

Genomic imprinting and fragile X-syndrome in psychiatric disorders.

1993 • 1 citations