Pathological Findings in Human Autoimmune Lymphoproliferative Syndrome

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

1994 • 1,549 citations

Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1995 • 1,477 citations

Mutations in Fas Associated with Human Lymphoproliferative Syndrome and Autoimmunity

1995 • 1,306 citations

FasGene Mutations in the Canale–Smith Syndrome, an Inherited Lymphoproliferative Disorder Associated with Autoimmunity

1996 • 486 citations

Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease.

1996 • 473 citations

T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis.

1989 • 402 citations

Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

1995 • 377 citations

Clinical, Immunologic, and Genetic Features of an Autoimmune Lymphoproliferative Syndrome Associated With Abnormal Lymphocyte Apoptosis

1997 • 374 citations

The mouse fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

1994 • 335 citations

A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease.

1992 • 310 citations

A simplified method of detection of clonal rearrangements of the T-cell receptor-gamma chain gene.

1992 • 261 citations

Enhanced and accelerated lymphoproliferation in Fas-null mice.

1996 • 211 citations

Clinical, immunological, and pathological consequences of Fas-deficient conditions

1996 • 184 citations

Deficiency of the Fas Apoptosis Pathway Without Fas Gene Mutations in Pediatric Patients With Autoimmunity/Lymphoproliferation

1997 • 177 citations

Chronic lymphadenopathy simulating malignant lymphoma

1966 • 159 citations

Histiocyte-Rich B-Cell Lymphoma

1992 • 150 citations

Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations.

1985 • 145 citations

Large B‐cell lymphoma rich in T‐cells and simulating Hodgkin's disease

1991 • 114 citations

The clinical spectrum in a large kindred with autoimmune lymphoproliferative syndrome caused by a Fas mutation that impairs lymphocyte apoptosis

1998 • 112 citations

Characteristic T helper 2 T cell cytokine abnormalities in autoimmune lymphoproliferative syndrome, a syndrome marked by defective apoptosis and humoral autoimmunity.

1997 • 110 citations

Human CD3+ T lymphocytes that express neither CD4 nor CD8 antigens.

1986 • 103 citations

Novel T-Lymphocyte Population in Combined Immunodeficiency with Features of Graft-versus-Host Disease

1989 • 96 citations

A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice

1994 • 81 citations

Loss of activation-induced CD45RO with maintenance of CD45RA expression during prolonged culture of T cells and NK cells.

1991 • 73 citations

Double-negative (CD4-CD8-) lymphocytes bearing T-cell receptor alpha and beta chains in normal human skin.

1989 • 70 citations

Chronic treatment of C3H-lpr/lpr and C3H-gld/gld mice with anti-CD8 monoclonal antibody prevents the accumulation of double negative T cells but not autoantibody production.

1994 • 56 citations

In CD8+ T cell-deficient lpr/lpr mice, CD4+B220+ and CD4+B220- T cells replace B220+ double-negative T cells as the predominant populations in enlarged lymph nodes.

1995 • 53 citations

Basic biology of autoimmune phenomena in chronic lymphocytic leukemia.

1998 • 47 citations

Marginal Zone B-Cell Lymphoma With Monocytoid B-Cell Lymphocytes in Pediatric Patients Without Immunodeficiency:A Report of Two Cases

1997 • 32 citations

Differentiation of human mature thymocytes: Existence of a T3⁺4⁻8⁻ intermediate stage

1986 • 29 citations

High Correlations of Anti-CMV Titers with Lymphocyte Activation Status and CD57 Antibody-Binding Capacity as Estimated with Three-Color, Quantitative Flow Cytometry in Blood Donors

1995 • 24 citations

Epstein‐Barr virus strain type and latent membrane protein 1 gene deletions in lymphomas in patients with rheumatic diseases

1997 • 13 citations

Hereditary splenomegaly with hypersplenism

1974 • 12 citations