Endocytosis: a review of mechanisms and plasma membrane dynamics

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

EVIDENCE FOR RECYCLING OF SYNAPTIC VESICLE MEMBRANE DURING TRANSMITTER RELEASE AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 2,122 citations

Coated pits, coated vesicles, and receptor-mediated endocytosis

1979 • 2,073 citations

THE ORGANIZATION OF PROTEINS IN THE HUMAN RED BLOOD CELL MEMBRANE

1974 • 1,554 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Endocytosis

1977 • 1,275 citations

The Biochemical Basis of Phagocytosis

1959 • 1,240 citations

The Role of Surface Carbohydrates in the Hepatic Recognition and Transport of Circulating Glycoproteins

1974 • 1,200 citations

Membrane Asymmetry

1977 • 965 citations

Transmembrane control of the receptors on normal and tumor cells

1976 • 951 citations

FUNCTIONS OF COATED VESICLES DURING PROTEIN ABSORPTION IN THE RAT VAS DEFERENS

1967 • 825 citations

Receptor-mediated endocytosis: insights from the lipoprotein receptor system.

1979 • 701 citations

Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts

1977 • 688 citations

Clathrin: a unique protein associated with intracellular transfer of membrane by coated vesicles.

1976 • 663 citations

Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte

1980 • 645 citations

Membrane flow during pinocytosis. A stereologic analysis.

1976 • 639 citations

Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans

1976 • 618 citations

Studies on the mechanism of phagocytosis. I. Requirements for circumferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane.

1975 • 595 citations

Dynamics of Insulin Secretion by the Perfused Rat Pancreas

1968 • 593 citations

Evidence for receptor-mediated binding of glycoproteins, glycoconjugates, and lysosomal glycosidases by alveolar macrophages.

1978 • 593 citations

Coated vesicles from pig brain: Purification and biochemical characterization

1975 • 564 citations

METABOLIC PATTERNS IN THREE TYPES OF PHAGOCYTIZING CELLS

1963 • 500 citations

The galactose-specific recognition system of mammalian liver: The route of ligand internalization in rat hepatocytes

1980 • 484 citations

Stimulus—secretion coupling in a neurosecretory organ: the role of calcium in the release of vasopressin from the neurohypophysis

1964 • 475 citations

Comparative studies of intracellular transport of secretory proteins.

1978 • 452 citations

Clathrin-coated vesicles: Isolation, dissociation and factor-dependent reassociation of clathrin baskets

1979 • 450 citations

THE "VESICLE IN A BASKET"

1969 • 445 citations

Phagocytosis as a Surface Phenomenon

1978 • 438 citations

THE INTERACTION OF SOLUBLE HORSERADISH PEROXIDASE WITH MOUSE PERITONEAL MACROPHAGES IN VITRO

1972 • 431 citations

Plasma cell immunoglobulin secretion. Arrest is accompanied by alterations the golgi complex

1977 • 404 citations

The receptosome: An intermediate organelle of receptor-mediated endocytosis in cultured fibroblasts

1980 • 398 citations

PINOCYTOSIS IN FIBROBLASTS

1974 • 389 citations

Receptor-Mediated Endocytosis of Hormones in Cultured Cells

1981 • 388 citations

Role of lysosomal acid lipase in the metabolism of plasma low density lipoprotein. Observations in cultured fibroblasts from a patient with cholesteryl ester storage disease.

1975 • 382 citations

Collection of insulin, EGF and α2-Macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization

1978 • 372 citations

Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor.

1979 • 325 citations

Studies on the mechanism of phagocytosis. II. The interaction of macrophages with anti-immunoglobulin IgG-coated bone marrow-derived lymphocytes.

1976 • 296 citations

Uptake of Protein by Mammalian Cells: An Underdeveloped Area

1968 • 290 citations

INHIBITION OF PHAGOCYTOSIS AND PLASMA MEMBRANE MOBILITY OF THE CULTIVATED MACROPHAGE BY CYTOCHALASIN B

1974 • 289 citations

Interactions of actin, myosin, and a new actin-binding protein of rabbit pulmonary macrophages. II. Role in cytoplasmic movement and phagocytosis.

1976 • 289 citations

A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts

1977 • 280 citations

MEMBRANES OF ANIMAL CELLS

1968 • 275 citations

SUBPLASMALEMMAL MICROFILAMENTS AND MICROTUBULES IN RESTING AND PHAGOCYTIZING CULTIVATED MACROPHAGES

1973 • 260 citations

Ca2+ control of actin gelation. Interaction of gelsolin with actin filaments and regulation of actin gelation.

1980 • 260 citations

INTERACTIONS BETWEEN RABBIT POLYMORPHONUCLEAR LEUCOCYTES AND STAPHYLOCOCCI

1959 • 257 citations

Receptors for human γG Globulin on human neutrophils

1970 • 250 citations

Effects of immobilized immune complexes on Fc- and complement-receptor function in resident and thioglycollate-elicited mouse peritoneal macrophages.

1979 • 238 citations

Directed lipid flow in cell membranes

1976 • 235 citations

alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions.

1979 • 232 citations

Quantitative Studies of Phagocytosis by Polymorphonuclear Leukocytes: Use of Emulsions to Measure the Initial Rate of Phagocytosis

1972 • 230 citations

The dissociation of the attachment and ingestion phases of phagocytosis by macrophages

1967 • 228 citations

Subcellular Particles.

1960 • 221 citations

EFFECTS OF CONCANAVALIN A ON MOUSE PERITONEAL MACROPHAGES

1974 • 219 citations

Exocytosis of pinocytosed fluid in cultured cells: kinetic evidence for rapid turnover and compartmentation.

1981 • 215 citations

The transport of lysosomal enzymes

1977 • 214 citations

FUNCTIONAL AND METABOLIC PROPERTIES OF POLYMORPHONUCLEAR LEUCOCYTES

1960 • 210 citations

QUANTITATIVE STUDIES OF PHAGOCYTOSIS

1973 • 210 citations

Neutrophil Receptors for IgG and Complement: Their Roles in the Attachment and Ingestion Phases of Phagocytosis

1976 • 210 citations

Plasma Membrane Synthesis in the Macrophage following Phagocytosis of Polystyrene Latex Particles

1972 • 208 citations

Receptors for Immunoglobulin and Complement on Human Alveolar Macrophages

1975 • 208 citations

THE REGULATION OF PINOCYTOSIS IN MOUSE MACROPHAGES

1967 • 208 citations

Coated pits act as molecular filters.

1980 • 208 citations

EFFECT OF PHAGOCYTOSIS ON MEMBRANE TRANSPORT OF NONELECTROLYTES

1971 • 190 citations

Biochemical and immunological characterization of human opsonic alpha2SB glycoprotein: its identity with cold-insoluble globulin.

1978 • 187 citations

Surface functions during mitosis I: Phagocytosis, pinocytosis and mobility of surface-bound ConA

1978 • 185 citations

SEGMENTAL RESPONSE OF THE MACROPHAGE PLASMA MEMBRANE TO A PHAGOCYTIC STIMULUS

1974 • 182 citations

Effects of calcium omission on acetylcholine-stimulated amylase secretion and phospholipid synthesis in pigeon pancreas slices

1966 • 179 citations

Mechanism of phagocytosis in dictyostelium discoideum: phagocytosis is mediated by different recognition sites as disclosed by mutants with altered phagocytotic properties

1980 • 175 citations

Distribution of actin-binding protein and myosin in macrophages during spreading and phagocytosis.

1980 • 175 citations

Fibronectin-mediated uptake of gelatin-coated latex particles by peritoneal macrophages.

1980 • 172 citations

THE UPTAKE AND DIGESTION OF IODINATED HUMAN SERUM ALBUMIN BY MACROPHAGES IN VITRO

1967 • 172 citations

Mediation of pinocytosis in cultured arterial smooth muscle and endothelial cells by platelet-derived growth factor

1978 • 171 citations

Effects of Phagocytosis and Colchicine on the Distribution of Lectin-Binding Sites on Cell Surfaces

1974 • 170 citations

The membrane proteins of the vacuolar system. II. Bidirectional flow between secondary lysosomes and plasma membrane.

1980 • 165 citations

2-Deoxyglucose selectively inhibits Fc and complement receptor-mediated phagocytosis in mouse peritoneal macrophages. I. Description of the inhibitory effect.

1976 • 158 citations

A macrophage receptor for (mannose/glucosamine)-glycoproteins of potential importance in phagocytic activity

1980 • 155 citations

PARTICLE UPTAKE BY POLYMORPHONUCLEAR LEUCOCYTES AND EHRLICH ASCITES-CARCINOMA CELLS

1963 • 153 citations

Quantitative studies of pinocytosis. I. Kinetics of uptake of (125I)polyvinylpyrrolidone by rat yolk sac cultured in vitro.

1975 • 151 citations

MEASUREMENT OF RATES OF PHAGOCYTOSIS

1969 • 147 citations

The pinocytic rate of activated macrophages.

1975 • 147 citations

Fate of plasma membrane during endocytosis. II. Evidence for recycling (shuttle) of plasma membrane constituents

1979 • 145 citations

Externally disposed plasma membrane proteins. II. Metabolic fate of iodinated polypeptides of mouse L cells.

1975 • 140 citations

Receptor-mediated uptake of 3,3',5-triiodo-L-thyronine by cultured fibroblasts.

1980 • 138 citations

Surface functions during mitosis. II. Quantitation of pinocytosis and kinetic characterization of the mitotic cycle with a new fluorescence technique.

1980 • 136 citations

On the structural and functional components of coated vesicles

1978 • 135 citations

Coated vesicles: characterization, selective dissociation, and reassembly.

1978 • 134 citations

Contractile basis of ameboid movement. VII. Aequorin luminescence during ameboid movement, endocytosis, and capping.

1980 • 133 citations

Selective iodination and polypeptide composition of pinocytic vesicles.

1980 • 130 citations

2-Deoxyglucose selectively inhibits Fc and complement receptor-mediated phagocytosis in mouse peritoneal macrophages II. Dissociation of the inhibitory effects of 2-deoxyglucose on phagocytosis and ATP generation.

1976 • 123 citations

Kinetics of phagocytosis of Staphylococcus aureus and Escherichia coli by human granulocytes.

1979 • 120 citations

Exocytosis-Endocytosis Coupling in the Pancreatic Beta Cell

1973 • 115 citations

Opsonin-Independent Phagocytosis of Activators of the Alternative Complement Pathway by Human Monocytes

1978 • 114 citations

Plasma Membrane: Substructural Changes Correlated with Electrical Resistance and Pinocytosis

1967 • 111 citations

THE IN VITRO DIFFERENTIATION OF MONONUCLEAR PHAGOCYTES

1965 • 106 citations

Studies on the Role of Phospholipids in Phagocytosis

1966 • 106 citations

Augmentation of macrophage complement receptor function in vitro. I. Characterization of the cellular interactions required for the generation of a T-lymphocyte product that enhances macrophage complement receptor function.

1979 • 106 citations

Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages.

1980 • 103 citations

PINOCYTOSIS IN ACANTHAMOEBA CASTELLANII

1972 • 99 citations

Contractile basis of ameboid movement. VII. The distribution of fluorescently labeled actin in living amebas.

1980 • 97 citations

The membrane proteins of the vacuolar system I. Analysis of a novel method of intralysosomal iodination.

1980 • 93 citations

Phagocytosis requires repeated triggering of macrophage phagocytic receptors during particle ingestion

1981 • 91 citations

A lectin-like receptor on mammalian macrophages

1978 • 85 citations

Recognition and response in mononuclear and granular phagocytes.

1976 • 82 citations

IMMUNOINHIBITION OF INTRACELLULAR PROTEIN DIGESTION IN MACROPHAGES

1973 • 82 citations

Defective Fc receptor-mediated phagocytosis in C3H/HeJ macrophages. I. Correction by lymphokine-induced stimulation.

1979 • 82 citations

Attachment and ingestion of gonococci human neutrophils

1975 • 82 citations

Augmentation of macrophage complement receptor function in vitro. III. C3b receptors that promote phagocytosis migrate within the plane of the macrophage plasma membrane.

1981 • 78 citations

THE REGULATION OF PINOCYTOSIS IN MOUSE MACROPHAGES

1967 • 76 citations

The pinocytosis of 125I-labelled poly(vinylpyrrolidone), [14C]sucrose and colloidal [198Au]gold by rat yolk sac cultured in vitro

1977 • 72 citations

Polarization of endocytosis and receptor topography on cultured macrophages.

1980 • 71 citations

Function of coated membranes and multivesicular bodies during membrane regulation in stimulated exocrine pancreas cells

1974 • 71 citations

Augmentation of macrophage complement receptor function in vitro. II. Characterization of the effects of a unique lymphokine upon the phagocytic capabilities of macrophages.

1980 • 66 citations

A quantitative study of pinocytosis and intracellular proteolysis in rat peritoneal macrophages

1977 • 66 citations

Partition of Salmonella typhimurium in a Two-Polymer Aqueous Phase System in Relation to Liability to Phagocytosis

1973 • 65 citations

Modulation of Fc-Mediated Phagocytosis by Cyclic AMP and Insulin in a Macrophage-Like Cell Line

1977 • 65 citations

Disappearance of macrophage surface folds after antibody-dependent phagocytosis.

1981 • 64 citations

Reduction of phagocytosis, surface hydrophobicity and charge of Salmonella typhimurium 395 MR10 by reaction with secretory IgA (SIgA).

1979 • 63 citations

An antiserum specific for cholinergic synaptic vesicles from electric organ.

1980 • 63 citations

Isolation of variants in phagocytosis of a macrophage-like continuous cell line.

1977 • 62 citations

Comparison of pinocytosis and phagocytosis in Acanthamoeba castellanii

1977 • 62 citations

Disappearance and Recovery of Human Monocyte IgG Receptor Activity After Phagocytosis

1972 • 62 citations

Phagocytosis as a surface phenomenon. II. Contact angles and phagocytosis of encapsulated bacteria before and after opsonization by specific antiserum and complement.

1972 • 62 citations

THE MECHANISM OF PHAGOCYTOSIS

1982 • 61 citations

STUDIES ON PROTEIN UPTAKE BY ISOLATED TUMOR CELLS

1962 • 61 citations

Microinjection of anticlathrin antibodies into fibroblasts does not interfere with the receptor-mediated endocytosis of α2-macroglobulin

1981 • 60 citations

Endocytosis and chloroquine accumulation during the cell cycle of hepatoma cells in culture.

1979 • 60 citations

CERTAIN INTERFACIAL TENSION RELATIONS AND THE BEHAVIOR OF BACTERIA IN FILMS

1924 • 56 citations

Phagocytosis of Mutants of Salmonella Typhimurium by Rabbit Polymorphonuclear Cells

1972 • 55 citations

Concomitant but Not Causal Association Between Surface Charge and Inhibition of Phagocytosis by Cryptococcal Polysaccharide

1980 • 54 citations

Membrane sialic acid on target particles modulates their phagocytosis by a trypsin-sensitive mechanism on human monocytes.

1978 • 52 citations

The Utilization of Proteins by Cultured Human Cells

1960 • 51 citations

Specific antibody-dependent phagocytosis of lipid vesicles by RAW264 macrophages results in the loss of cell surface Fc but not C3b receptor activity.

1980 • 51 citations

Ultrastructural immunocytochemical localization of clathrin in cultured fibroblasts

1981 • 51 citations

Non-specific recognition in phagocytosis: ingestion of aldehyde-treated erythrocytes by rat peritoneal macrophages.

1979 • 51 citations

Physiochemical consequences of opsonization of Salmonella typhimurium with hyperimmune IgG and complement.

1977 • 50 citations

Defective Fc-mediated phagocytosis in C3H/HeJ macrophages. II. Correction by cAMP agonists.

1981 • 48 citations

Influence of temperature on opsonization and phagocytosis of staphylococci

1977 • 48 citations

The mechanism of release of catecholamines from the adrenal medulla.

1966 • 46 citations

THE ROLE OF CELL WALL CARBOHYDRATES IN BINDING OF MICROORGANISMS TO MOUSE PERITONEAL EXUDATE MACROPHAGES

1978 • 42 citations

Phagocytosis: A Review

1978 • 41 citations

Factors in the partition of red blood cells in aqueous dextran-polyethylene glycol two-phase systems

1968 • 41 citations

Pinocytosis and locomotion of amoebae: XII. Dynamics and motive force generation during induced pinocytosis in A. proteus

1979 • 41 citations

Properties of protein kinase and adenylate cyclase‐deficient variants of a macrophage‐like cell line

1979 • 38 citations

The regional association of actin and myosin with sites of particle phagocytosis

1979 • 34 citations

SURFACE‐CHARGE CHARACTERISTICS OF SMOOTH AND ROUGH SALMONELLA TYPHIMURIUM BACTERIA DETERMINED BY AQUEOUS TWO‐PHASE PARTITIONING AND FREE ZONE ELECTROPHORESIS

1977 • 34 citations

Phagocytosis: quantification of rates and intercellular heterogeneity

1977 • 34 citations

Protein turnover in pulmonary macrophages Utilization of amino acids derived from protein degradation

1981 • 32 citations

Sucrose uptake by pinocytosis in Amoeba proteus and the influence of external calcium.

1979 • 30 citations

Alteration of macrophage interfacial tension by supernatants of antigen-activated lymphocyte cultures.

1973 • 29 citations

Macrophage phagocytosis: analysis of particle binding and internalization

1982 • 28 citations

Influence of Hyperimmune Immunoglobulin G on the Physicochemical Properties of the Surface of Salmonella typhimurium 395 MS in Relation to Interaction with Phagocytic Cells

1974 • 26 citations

Pinocytic activity of rabbit alveolar macrophages in vitro.

1978 • 26 citations

Phagocytosis by macrophages: II. The dissociation of the attachment and ingestion steps

1981 • 23 citations

Uptake by Mononuclear Phagocytes of Protein-Coated Bentonite Particles Stabilized with a Carbodiimide

1967 • 23 citations

A micromethod for evaluating the phagocytic activity of human macrophages by ingestion of radio-labelled polystyrene particles

1976 • 22 citations

Methods to quantify endocytosis: a review.

1980 • 22 citations

Biochemical basis of phagocytosis. V. Effect of phagocytosis on cellular uptake of extracellular fluid, and on the intracellular pool of L-alpha-glycerophosphate.

1966 • 21 citations

Endocytotic Sucrose Uptake in Amoeba proteus Induced with the Calcium Ionophore A23187

1980 • 20 citations

IgM-Fc receptor-mediated phagocytosis of rat macrophages.

1981 • 19 citations

Phagocytosis as a Surface Phenomenon. IV. The Minimum Size and Composition of Antigen-Antibody Complexes that can Become Phagocytized

1974 • 14 citations

Endocytosis in Chinese hamster fibroblasts

1973 • 12 citations

Use of Radioactive Isotopes in Studies on Phagocytosis in vitro

1966 • 12 citations

The utilization of a written family history questionnaire in genetic counseling.

1978 • 9 citations

The uptake of IgG and IgM coated sheep erythrocytes in perfused rabbit liver.

1978 • 9 citations

Role of macrophage receptors in the ingestion phase of phagocytosis.

1978 • 8 citations

Bulk Solute Extrusion as a Mechanism Conferring Solute Uptake Specificity by Pinocytosis in Amoeba proteus

1981 • 8 citations

Role of surface wettability in phagocytosis of Neurospora crassa spores.

1979 • 4 citations