Can Dietary Selenium Modify Cancer Risk?

PREDIAGNOSTIC SERUM SELENIUM AND RISK OF CANCER

1983 • 556 citations

Cancer mortality correlation studies-III: Statistical associations with dietary selenium intakes

1977 • 497 citations

Antioxidants and Cancer

1976 • 329 citations

Risk of cancer in relation to serum concentrations of selenium and vitamins A and E: matched case-control analysis of prospective data.

1985 • 322 citations

ASSOCIATION BETWEEN SERUM SELENIUM AND THE RISK OF CANCER

1984 • 287 citations

Selenium Distribution and Human Cancer Mortality

1971 • 266 citations

Relationship of Selenium to Cancer. I. Inhibitory Effect of Selenium on Carcinogenesis

1970 • 259 citations

Selenium in crops in the United States in relation to selenium-responsive diseases of animals

1967 • 225 citations

Antioxidants and Cancer. I. Selenium in the Blood of Normals and Cancer Patients

1973 • 193 citations

Synergistic effect of vitamin E and selenium in the chemoprevention of mammary carcinogenesis in rats.

1983 • 171 citations

Catalytic Oxidation of Glutathione and Other Sulfhydryl Compounds by Selenite

1958 • 171 citations

Selenium, Molybdenum, and Vanadium in Human Blood

1968 • 169 citations

Inhibitory effects of selenium on 1,2-dimethylhydrazine and methylazoxymethanol acetate induction of colon tumors

1977 • 168 citations

Diet and azo dye tumors; effect of diet during a period when the dye is not fed.

1949 • 166 citations

Liver Tumors Following Cirrhosis Caused by Selenium in Rats

1943 • 165 citations

Cancer mortality correlation studies-IV: Associations with dietary intakes and blood levels of certain trace elements, notably se-antagonists

1977 • 161 citations

Serum Levels of Selenium, Calcium, Copper Magnesium, Manganese and Zinc in Various Human Diseases

1979 • 157 citations

Effects of selenium and of arsenic on the genesis of spontaneous mammary tumors in inbred C3H mice.

1974 • 149 citations

Blood selenium and glutathione peroxidase activity in normal subjects and in surgical patients with and without cancer in New Zealand

1979 • 136 citations

Effects of selenium on azo dye hepatocarcinogenesis

1977 • 131 citations

Antioxidants reduce the mutagenic effect of malonaldehyde and β-propiolactone

1979 • 125 citations

Relationship between serum selenium levels and patients with carcinoma

1976 • 119 citations

Selenium effects on the carcinogenicity and metabolism of 2-acetylaminofluorene

1979 • 117 citations

Selenium Levels in Human Blood and Tissues in Health and in Disease

1975 • 112 citations

Inhibitory effects of selenium on the growth of L1210 leukemic cells.

1981 • 110 citations

Enhancement of mammary tumorigenesis by dietary selenium deficiency in rats with a high polyunsaturated fat intake.

1981 • 106 citations

Inhibition of the genesis of spontaneous mammary tumors in C3H mice: effects of selenium and of selenium-antagonistic elements and their possible role in human breast cancer

1976 • 105 citations

Effect of Dietary Selenium on N-2 Fluorenyl-Acetamide (FAA)-Induced Cancer in Vitamin E Supplemented, Selenium Depleted Rats

1972 • 104 citations

Inhibitory effects of selenium on the mutagenicity of 2-acetylaminofluorene (AAF) and AAF derivatives

1977 • 100 citations

Selenium and Tellurium in Rats: Effect on Growth, Survival and Tumors

1971 • 97 citations

Effect of retinoic acid, butylated hydroxytoluene, selenium and sorbic acid on azo-dye hepatocarcinogenesis

1980 • 96 citations

Plasma selenium and skin neoplasms: A case‐control study

1985 • 94 citations

Regional variation of cancer mortality incidence and its relation to selenium levels in China

1985 • 93 citations

Selenium-mediated inhibition of mouse mammary tumorigenesis

1980 • 89 citations

Effect of an inorganic and organic form of dietary selenium on the promotional stage of mammary carcinogenesis in the rat.

1984 • 85 citations

Selenium-mediated inhibition of 7,12-dimethylbenz[a]anthracene-induced mouse mammary tumorigenesis

1981 • 82 citations

Selenium Inhibition of <italic>N</italic>-Methyl-<italic>N</italic>-nitrosourea-Induced Mammary Carcinogenesis in the Rat<xref ref-type="fn" rid="fn2">2</xref>, <xref ref-type="fn" rid="fn3">3</xref>, <xref ref-type="fn" rid="fn4">4</xref>

1980 • 81 citations

Factors Influencing the Antitumorigenic Properties of Selenium in Mice

1983 • 80 citations

Factors influencing the anticarcinogenic efficacy of selenium in dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats.

1981 • 79 citations

Biochemical and clinical effects of selenium on dimethylhydrazine-induced colon cancer in rats.

1981 • 77 citations

Chemoprevention of mammary tumorigenesis by a combined regimen of selenium and vitamin A

1981 • 75 citations

Anticarcinogenic effect of selenium in rats treated with dimethylbenz[a]anthracene and fed different levels and types of fat

1981 • 74 citations

Relationship of Dietary Selenium Concentration; Chemical Cancer Induction; and Tissue Concentration of Selenium in Rats

1973 • 73 citations

Inhibition by dietary selenium of colon cancer induced in the rat by bis(2-oxopropyl)nitrosamine.

1982 • 72 citations

Effects of temporary selenium supplementation on the genesis of spontaneous mammary tumors in inbred female C₃H/St mice

1980 • 72 citations

The relationship of dietary selenium and breast cancer

1980 • 69 citations

Effect of selenium on azoxymethane-induced intestinal cancer in rats fed high fat diet

1981 • 64 citations

Selenium inhibition of 1,2-dimethylhydrazine-induced colon carcinogenesis.

1983 • 60 citations

Effect of combined selenium and retinyl acetate treatment on mammary carcinogenesis.

1981 • 60 citations

Selenium inhibition of DNA synthesis in mouse mammary epithelial cell line YN-4.

1984 • 59 citations

Adaptive Changes in Hepatic Glutathione Metabolism in Response to Excess Selenium in Rats

1983 • 56 citations

Selenium and the genesis of murine mammary tumors

1981 • 50 citations

Effects of Dietary Selenium and Vitamin E on Hepatic Mixed-Function Oxidase Activities and In Vivo Covalent Binding of Aflatoxin B1 in Rats

1982 • 50 citations

Effects of Dietary Selenium and Vitamin E on Covalent Binding of Aflatoxin to Chick Liver Cell Macromolecules

1982 • 49 citations

Serum selenium and glutathione peroxidase, and plasma lipid peroxides in uterine, ovarian or vulvar cancer, and their responses to antioxidants in patients with ovarian cancer

1984 • 48 citations

Studies on the inhibition of protein synthesis by selenodiglutathione

1979 • 48 citations

Inhibition of in vitro amino acid incorporation by sodium selenite

1974 • 47 citations

Effect of selenium on growth rate of canine mammary carcinoma cells in athymic nude mice

1982 • 44 citations

Dietary selenium intake and growth of the MT-W9B transplantable rat mammary tumor

1981 • 43 citations

Effect of short-term feeding of sodium selenite on 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in the rat.

1982 • 41 citations

The effect of various seleno-compounds on ehrlich ascites tumor cells

1979 • 40 citations

Serum Selenium Levels in Malignant Lymphoproliferative Diseases

1980 • 39 citations

Serum selenium in patients with ovarian cancer during and after therapy

1984 • 39 citations

Serum selenium and reticuloendothelial tumors

1978 • 39 citations

Effect of graded dietary levels of selenium on tracheal carcinomas induced by 1-methyl-1-nitrosourea

1979 • 38 citations

Effect of selenium on the induction of breast fibroadenomas by adenovirus type 9 and 1,2‐dimethylhydrazine‐induced bowel carcinogenesis in rats

1982 • 36 citations

Inhibition of the growth of malignant mouse lymphoid cells by selenodiglutathione and selenodicysteine

1981 • 33 citations

Selenium and cancer: Chemical interpretation of a plasma “cancer test”

1973 • 33 citations

Modification of mammary carcinogenesis and tissue peroxidation by selenium deficiency and dietary fat

1981 • 31 citations

Red blood cell and serum selenium concentrations as influenced by age and selected diseases.

1983 • 31 citations

Stage specificity of selenium-mediated inhibition of mouse mammary tumorigenesis

1983 • 31 citations

Elongation factor 2 as the target of the reaction product between sodium selenite and glutathione (GSSeSG) in the inhibiting of amino acid incorporation in vitro

1975 • 31 citations

The effects of dietary selenium on the biotransformation of 7,12-dimethylbenz[a]anthracene

1982 • 30 citations

Selenium and the acute effects of the carcinogens, 2-acetylaminofluorene and methylazoxymethanol acetate.

1982 • 27 citations

Selenium status of vegetarians, nonvegetarians, and hormone-dependent cancer subjects

1983 • 26 citations

Gastrointestinal Cancer: Epidemiology and Experimental Studies

1978 • 26 citations

Inhibitory effects of selenium on mutagenicity

1984 • 25 citations

Selenium and the transplantable tumor

1984 • 24 citations

The distribution of selenium and cancer mortality in the continental United States

1983 • 24 citations

Effect of dietary selenium on the metabolism and excretion of 2‐acetylaminofluorene in the rat

1982 • 22 citations

Blood selenium concentration in residents of areas in China having a high incidence of lung cancer

1984 • 21 citations

Influence of dietary vitamin E and selenium on metabolic activation of chemicals to mutagens

1984 • 17 citations

Selenium modified mutagenicity and metabolism of benzo[a]pyrene in an S9-dependent system

1984 • 16 citations

Selenium inhibition of the neoplastic transformation in preneoplastic mammary cell populations

1984 • 15 citations

Dietary selenium, hepatic arylhydrocarbon hydroxylase and mutagenic activation of benzo(a)pyrene, 2-aminoanthracene and 2-aminofluorene

1982 • 14 citations

Different effects of selenium on cyclic AMP metabolism in hepatoma cells and normal liver cells

1983 • 13 citations

Dietary selenium deficiency causes decreased N-oxygenation of N,N-dimethylaniline and increased mutagenicity of diemthylnitrosamine in the isolated rat liver/cell culture system

1984 • 9 citations