oriP is essential for EBNA gene promoter activity in Epstein-Barr virus-immortalized lymphoblastoid cell lines

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1987 • 5,745 citations

DNA sequence and expression of the B95-8 Epstein—Barr virus genome

1984 • 2,039 citations

Epstein-Barr virus and its replication

1996 • 1,621 citations

Stable replication of plasmids derived from Epstein–Barr virus in various mammalian cells

1985 • 1,303 citations

Enhancement of the Infectivity of Simian Virus 40 Deoxyribonucleic Acid With Diethylaminoethyl-Dextran<xref ref-type="fn" rid="FN2">2</xref>

1968 • 781 citations

A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells.

1984 • 685 citations

Genetic analysis of immortalizing functions of Epstein–Barr virus in human B lymphocytes

1989 • 553 citations

Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation.

1989 • 491 citations

Mediation of Epstein-Barr Virus EBNA2 Transactivation by Recombination Signal-Binding Protein J _κ

1994 • 462 citations

Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.

1987 • 397 citations

trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1.

1986 • 363 citations

The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein.

1994 • 352 citations

Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1

1990 • 319 citations

Establishment in continuous culture of a new type of lymphocyte from a “burkitt‐like” malignant lymphoma (line d.g.‐75)

1977 • 286 citations

An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking.

1994 • 262 citations

B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2.

1995 • 255 citations

A promoter of Epstein-Barr virus that can function during latent infection can be transactivated by EBNA-1, a viral protein required for viral DNA replication during latent infection

1989 • 254 citations

Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1

1995 • 250 citations

An Epstein-Barr virus-producer line Akata: Establishment of the cell line and analysis of viral DNA

1991 • 233 citations

Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein

1990 • 208 citations

Non-immortalizing P3J-HR-1 Epstein-Barr virus: a deletion mutant of its transforming parent, Jijoye

1982 • 204 citations

Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes.

1990 • 196 citations

The Epstein-Barr virus immortalizing protein EBNA-2 is targeted to DNA by a cellular enhancer-binding protein.

1993 • 187 citations

An EBNA-1-dependent enhancer acts from a distance of 10 kilobase pairs to increase expression of the Epstein-Barr virus LMP gene

1995 • 185 citations

trans Activation of an Epstein-Barr Viral Transcriptional Enhancer by the Epstein-Barr Viral Nuclear Antigen 1

1986 • 176 citations

The level of c-fgr RNA is increased by EBNA-2, an Epstein-Barr virus gene required for B-cell immortalization

1990 • 168 citations

Epstein-Barr virus-encoded nuclear antigen 2 activates the viral latent membrane protein promoter by modulating the activity of a negative regulatory element.

1990 • 168 citations

Epstein-Barr virus nuclear protein 3C modulates transcription through interaction with the sequence-specific DNA-binding protein J kappa

1995 • 167 citations

Epstein-Barr virus nuclear antigen 2 activates transcription of the terminal protein gene

1991 • 165 citations

EBNA-2 transactivates a lymphoid-specific enhancer in the BamHI C promoter of Epstein-Barr virus

1991 • 158 citations

The Epstein-Barr virus nuclear antigen 2 interacts with an EBNA2 responsive cis-element of the terminal protein 1 gene promoter.

1993 • 144 citations

Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection.

1991 • 142 citations

Influence of Burkitt's lymphoma and primary B cells on latent gene expression by the nonimmortalizing P3J-HR-1 strain of Epstein-Barr virus

1989 • 124 citations

Epstein-Barr virus nuclear protein 2 transactivates a cis-acting CD23 DNA element

1991 • 124 citations

Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes.

1989 • 122 citations

Epstein-Barr virus nuclear antigen 3C is a transcriptional regulator

1995 • 114 citations

Organization of the Epstein-Barr virus DNA molecule. III. Location of the P3HR-1 deletion junction and characterization of the NotI repeat units that form part of the template for an abundant 12-O-tetradecanoylphorbol-13-acetate-induced mRNA transcript

1983 • 104 citations

[Epstein-Barr virus].

1993 • 64 citations

Transcription of the Epstein-Barr virus nuclear antigen 1 (EBNA1) gene occurs before induction of the BCR2 (Cp) EBNA gene promoter during the initial stages of infection in B cells

1996 • 39 citations

Molecular genetic analysis of Epstein-Barr virus Cp promoter function

1996 • 32 citations

Characterization of the deletion and rearrangement in the BamHI C region of the X50-7 Epstein-Barr virus genome, a mutant viral strain which exhibits constitutive BamHI W promoter activity

1992 • 23 citations