von Willebrand factor cleaving protease and ADAMTS13mutations in childhood TTP

Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

2001 • 1,715 citations

von Willebrand Factor–Cleaving Protease in Thrombotic Thrombocytopenic Purpura and the Hemolytic–Uremic Syndrome

1998 • 1,630 citations

Unusually Large Plasma Factor VIII: von Willebrand Factor Multimers in Chronic Relapsing Thrombotic Thrombocytopenic Purpura

1982 • 1,105 citations

THROMBOTIC THROMBOCYTOPENIC PURPURA

1966 • 905 citations

Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis

1996 • 893 citations

Structure of von Willebrand Factor-cleaving Protease (ADAMTS13), a Metalloprotease Involved in Thrombotic Thrombocytopenic Purpura

2001 • 827 citations

Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion

1996 • 785 citations

Thrombotic thrombocytopenic purpura : report of 16 cases and review of the literature

1966 • 764 citations

Purification of human von Willebrand factor–cleaving protease and its identification as a new member of the metalloproteinase family

2001 • 605 citations

Mutations and common polymorphisms in ADAMTS13 gene responsible for von Willebrand factor-cleaving protease activity

2002 • 407 citations

Hyaline thrombosis of the terminal arterioles and capillaries : a hitherto undescribed disease

1924 • 379 citations

Partial amino acid sequence of purified von Willebrand factor–cleaving protease

2001 • 371 citations

Hyalin thrombosis of the terminal arterioles and capillaries : A hitherto undescribed disease

1924 • 356 citations

Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor.

1990 • 347 citations

A Novel Human Metalloprotease Synthesized in the Liver and Secreted into the Blood: Possibly, the von Willebrand Factor--Cleaving Protease?

2001 • 335 citations

Von Willebrand factor–cleaving protease (ADAMTS13) in thrombocytopenic disorders: a severely deficient activity is specific for thrombotic thrombocytopenic purpura

2002 • 331 citations

Assay of von Willebrand Factor (vWF)-cleaving Protease Based on Decreased Collagen Binding Affinity of Degraded vWF

1999 • 303 citations

Congenital Deficiency of a Factor in Normal Plasma That Reverses Microangiopathic Hemolysis and Thrombocytopenia

1978 • 277 citations

Studies on Thrombopoiesis. I. A Factor in Normal Human Plasma Required for Platelet Production; Chronic Thrombocytopenia Due to its Deficiency

1960 • 252 citations

Recovery and Half-Life of von Willebrand Factor-Cleaving Protease after Plasma Therapy in Patients with Thrombotic Thrombocytopenic Purpura

1999 • 214 citations

Heterogeneity of plasma von Willebrand factor multimers resulting from proteolysis of the constituent subunit.

1991 • 205 citations

von Willebrand factor cleaving protease (ADAMTS13) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome

2002 • 198 citations

ATYPICAL CONGENITAL HAEMOLYTIC ANAEMIA

1953 • 104 citations

Expression and characterization of von Willebrand factor dimerization defects in different types of von Willebrand disease

2001 • 83 citations

Luminography – an Alternative Assay for Detection of von Willebrand Factor Multimers

1988 • 75 citations

Thrombotic thrombocytopenic purpura in four siblings

1975 • 56 citations

Remission of thrombotic thrombocytopenic purpura in a patient with compound heterozygous deficiency of von Willebrand factor-cleaving protease by infusion of solvent/detergent plasma

2002 • 35 citations

Remission of thrombotic thrombocytopenic purpura in a patient with compound heterozygous deficiency of von Willebrand factor‐cleaving protease by infusion of solvent/detergent plasma

2002 • 29 citations

New strategies in diagnosis and treatment of thrombotic thrombocytopenic purpura: case report and review

1999 • 25 citations

Hereditary Thrombotic Thrombocytopenic Purpura: Microangiopathic Hemolytic Anemia, Thrombocytopenia, and Renal Insufficiency Occurring in Consecutive Generations

1982 • 22 citations

Congenital microangiopathic hemolytic anemia: Report of a Japanese girl

1982 • 18 citations

Familial thrombotic microangiopathy.

1985 • 14 citations

Familial Thrombotic Microangiopathy

1985 • 2 citations