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THE EFFECT OF CNS DEPRESSANTS ON MITOSIS

Data up to Jan 2025

Published1966
Citations24
References180

Total Citations Per Year

Abstract

References (180)

Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism

1961 • 4,416 citations

THALIDOMIDE AND CONGENITAL ABNORMALITIES

1961 • 1,089 citations

Zur Theorie der Alkoholnarkose

1899 • 1,008 citations

An analysis of the syndrome of malformations induced by maternal vitamin a deficiency. Effects of restoration of vitamin a at various times during gestation

1953 • 754 citations

The pharmacological basis of therapeutics

1955 • 718 citations

Electrochemical aspects of physiological and pharmacological action in excitable cells. I. The resting cell and its alteration by extrinsic factors.

1958 • 579 citations

THE EFFECT OF COLCHICINE ON ROOT MITOSES IN ALLIUM

2010 • 564 citations

The use of chemical potentials as indices of toxicity

1939 • 550 citations

Mitosis and the Physiology of Cell Division

1961 • 549 citations

THE ACTION OF CARDIAC GLYCOSIDES ON ION MOVEMENTS.

1964 • 454 citations

A Molecular Theory of General Anesthesia

1961 • 432 citations

Colchicine in Agriculture, Medicine, Biology and Chemistry

1955 • 426 citations

Hydroxyurea: Inhibitory Effect on DNA Metabolism

1964 • 425 citations

Leçons sur les phénomènes de la vie communs aux animaux et aux végétaux

1878 • 387 citations

Experimental Production of Congenital Malformations in Mammals by Metabolic Procedure

1959 • 383 citations

Inhibition of Electron and Energy Transfer in Mitochondria

1963 • 363 citations

TREATMENT OF TETANUS SEVERE BONE-MARROW DEPRESSION AFTER PROLONGED NITROUS-OXIDE ANESTHESIA

1956 • 354 citations

Medicine and the Law

1966 • 308 citations

NUCLEIC ACID SYNTHESIS IN RELATION TO THE CELL DIVISION CYCLE*

1960 • 271 citations

Electrochemical aspects of physiological and pharmacological action in excitable cells. II. The action potential and excitation.

1958 • 240 citations

COLCHICINE MITOSIS, CHROMOSOME CONTRACTION, NARCOSIS AND PROTEIN CHAIN FOLDING

2010 • 188 citations

THE ENERGY RELATIONS OF MITOTIC ACTIVITY

1952 • 186 citations

METABOLIC INTERACTIONS BETWEEN L‐ASCORBIC ACID AND DRUGS

1961 • 176 citations

THE ANAPHASE MOVEMENT OF CHROMOSOMES IN THE SPERMATOCYTES OF THE GRASSHOPPER

1949 • 174 citations

INDUCTION OF CHROMOSOME FRAGMENTATION BY PHENOLS

2010 • 150 citations

Rumplessness of chicken embryos produced by the injection of insulin and other chemicals

1945 • 137 citations

Mitotic poisons and the cancer problem

1958 • 127 citations

THE MECHANISM OF C-MITOTIC ACTION OBSERVATIONS ON THE NAPHTHALENE SERIES

2010 • 115 citations

Barbiturates and oxidative phosphorylation

1960 • 114 citations

Narcosis and oxidations of the brain

1932 • 107 citations

AN INTERPRETATION OF TRANSPORT PHENOMENA AT MITOSIS*

1960 • 107 citations

IRRADIATION OF PARTS OF INDIVIDUAL CELLS. III. EFFECTS OF CHROMOSOMAL AND EXTRACHROMOSOMAL IRRADIATION ON CHROMOSOME MOVEMENTS

1955 • 102 citations

Narcotics and Brain Respiration

1954 • 100 citations

The Motility of Muscle and Cells

1958 • 96 citations

In Vivo Effects of Diagnostic X-Irradiation on Human Chromosomes

1964 • 94 citations

The effects of narcotics on tissue oxidations

1937 • 93 citations

Prenatal Influences on Tooth Development

1953 • 91 citations

Congenital Malformations Induced in Rats by Maternal Nutritional Deficiency

1942 • 90 citations

CARDIAC AND AORTIC ARCH ANOMALIES IN THE OFFSPRING OF VITAMIN A DEFICIENT RATS CORRELATED WITH SIMILAR HUMAN ANOMALIES

1950 • 85 citations

Carbohydrate – Amino-Acid Inter-Relations in Brain Cortex In Vitro

1959 • 85 citations

Studies on local anesthetics : Xylocaine : a new synthetic drug

1948 • 83 citations

The site of action of narcotics in respiratory processes

1941 • 81 citations

The Effect of Drugs on Cell Membranes with Special Reference to Local Anaesthetics

1961 • 81 citations

Effects of cardiac glyosides and other lactones, and of certain other compounds, on cation transfer in human erythrocytes.

1955 • 81 citations

Transport and Accumulation in Biological Systems

1957 • 79 citations

Multiple Congenital Abnormalities in the Rat Resulting from Riboflavin Deficiency Induced by the Antimetabolite Galactoflavin

1956 • 79 citations

NEW ASPECTS OF THE PHARMACOLOGY OF ANTIMITOTIC AGENTS.

1963 • 76 citations

ROLE OF ASCORBIC ACID IN MICROSOMAL ELECTRON TRANSPORT AND THE POSSIBLE RELATIONSHIP TO HYDROXYLATION REACTIONS

1961 • 74 citations

The Mechanism of Inhibition of Cellular Activity by Narcotics

1947 • 73 citations

Dynamics of Spindle Formation and Its Inhibition by Chemicals

1959 • 73 citations

Evaluation of the teratogenicity of drugs

1964 • 72 citations

Colchicine. I. General pharmacology.

1952 • 72 citations

A QUANTITATIVE STUDY OF ANAPHASE MOVEMENT IN THE APHID TAMALIA

1943 • 70 citations

METABOLIC ACTIVITIES AND CLEAVAGE OF EGGS OF THE SEA URCHIN, ARBACIA PUNCTULATA A REVIEW, 1932-1949

1950 • 68 citations

Die bedeutung des adenosintriphosphat für die zell-und kernteilungsbewegungen in der anaphase

1954 • 66 citations

The Natural Resistance of the Golden Hamster to Colchicine

1952 • 62 citations

Effects of Colchicine and Colchemid on Synthesis of Deoxyribonucleic Acid in the Skin of the Guinea Pig's Ear in vitro

1963 • 62 citations

Observations on inhibition of nucleic acid synthesis resulting from administration of nitrogen mustard, urethan,. colchicine, 2,6-diaminopurine, 8-azaguanine, potassium arsenite, and cortisone.

1951 • 61 citations

Inhibition of the brain microsomal adenosinetriphosphatase by depolarizing agents

1961 • 60 citations

On the reduction of externally added DPN by succinate in submitochondrial particles

1961 • 58 citations

THE EXTENSIVE SYNTHESIS OF THE METHYL GROUP OF THYMINE IN THE ADULT RAT1

1950 • 58 citations

Die glycerin-wasserextrahierte telophasezelle als modell der zytokinese

1954 • 58 citations

CHEMICALLY INDUCED CHROMOSOME REACTIONS IN ALLIUM CEPA AND VICIA FABA

1951 • 57 citations

The nucleoprotein content of fibroblasts growing in vitro. 4. Changes in the ribonucleic acid phosphorus (RNAP) and deoxyribonucleic acid phosphorus (DNAP) content

1949 • 57 citations

Different types of carcinogens and their possible modes of action: a review.

1952 • 54 citations

Cellular Effects of Anticancer Drugs

1963 • 53 citations

Resorption and loss of foetuses in rats living at 35° C

1957 • 52 citations

Crystallinity and dimensional changes in fibrous proteins

1957 • 52 citations

Alternative pathways of mitochondrial DPNH oxidation, studied with amytal.

1955 • 52 citations

ACTION OF VARIOUS SUBSTANCES ON THE MITOCHONDRIA OF LIVING CELLS CULTIVATED IN VITRO

1954 • 50 citations

Effect on Radiosensitivity of Inert Gases: Effect of Inert Gases on Oxygen-dependent Radiosensitivity

1958 • 49 citations

Prenatal Influences on Tooth Development

1953 • 49 citations

Studies on bone mechanics in vitro. I. Influence of pressure on orientation of structure

1938 • 48 citations

Nicotinic Acid Analogs: Effects on Response of Chick Embryos and Hens to Organophosphate Toxicants

1964 • 48 citations

The viscous elastic properties of smooth muscle

1926 • 48 citations

Zur Kenntnis der Mitose VIII

1939 • 48 citations

DISTURBANCES OF REPRODUCTION AND OVARIAN CHANGES IN THE GUINEA-PIG IN RELATION TO VITAMIN C DEFICIENCY

1933 • 46 citations

Effect of Nitrous Oxide on the White-Cell Count in Leukemia

1963 • 46 citations

Effects of anesthetics on oxygen consumption and on synaptic transmission in sympathetic ganglia

1952 • 45 citations

The Chemistry and Physics of Anesthesia

1962 • 42 citations

On the Mitotic Movements of Chromosomes

1956 • 42 citations

THE PRESENT STATUS OF THE THEORIES OF NARCOSIS

1930 • 42 citations

Changes in D-glucaric acid excretion induced by stimulators of ascorbic acid biosynthesis

1963 • 39 citations

An interference microscopical and cytochemical analysis of local mass changes in the mitotic apparatus during mitosis

1959 • 39 citations

Effects of Urethane on Mitosis in the Walker Rat Carcinoma

1954 • 39 citations

EFFECTS OF LOCAL ANAESTHETICS ON RESPIRATION OF RAT BRAIN CORTEX IN VITRO

1956 • 38 citations

Carbohydrate metabolism in insulin-treated chick embryos

1951 • 38 citations

The nucleoside triphosphate content of Tetrahymena pyriformis during the division cycle in synchronously dividing mass cultures

1958 • 37 citations

THE ENERGY REQUIREMENTS FOR MITOSIS*

1960 • 37 citations

Colchicine Teratogenesis in Hamster Embryos.

1963 • 37 citations

Epidermal Mitotic Activity and Oxygen Tension

1951 • 36 citations

Further observations on the ribonucleoproteins of mitotically dividing mammalian cells

1961 • 35 citations

THE PHYSIOLOGIC EFFECTS OF ETHYLENE

1923 • 34 citations

EFFECT OF MATERNAL RACHITOGENIC DIET ON SKELETAL DEVELOPMENT OF YOUNG RAT

1943 • 33 citations

STUDIES ON INHIBITION OF THE COLCHICINE EFFECT ON MITOSIS

1954 • 33 citations

Narcotics and Biological Acetylations

1953 • 33 citations

Specific inhibition by meso-inositol of the colchicine effect on rat fibroblasts

1951 • 33 citations

Inhibition of Bacterial Growth by Drugs of the Morphine Series

1964 • 33 citations

The mechanism of cell division:Experiments with ether on the sea urchin egg

1954 • 32 citations

EFFECTS OF ANESTHESIA ON METABOLISM AND CELLULAR FUNCTIONS. A WORKSHOP HELD UNDER THE COMMITTEE ON ANESTHESIA OF THE NATIONAL ACADEMY OF SCIENCES--NATIONAL RESEARCH COUNCIL.

1965 • 32 citations

ETHYLENE AS A GAS ANESTHETIC

1923 • 32 citations

Nature of Colchicine Resistance in Golden Hamster

1959 • 32 citations

Inhibition of Mitotic Poisoning by meso-Inositol

1948 • 32 citations

Chemotherapy of Cancer

1962 • 30 citations

SYNERGISTS AND ANTAGONISTS OF MITOTIC POISONS

1954 • 30 citations

Influence of Colchicine on the Form of Skeletal Muscle in Tissue Culture.

1953 • 30 citations

The Cytological Action of Ethylcarbamate (Urethane) and Other Carbamic Esters in Normal and Leukaemic Mice, and in Rabbits

1947 • 30 citations

CLINICAL EXPERIENCES WITH ETHYLENE-OXYGEN ANESTHESIA

1923 • 30 citations

A specific transplacental effect of urethane in mice.

1950 • 29 citations

Ethylene as a Gas Anesthetic*

1923 • 28 citations

NUTRITIONAL AND ENZYMATIC STUDIES ON THE MECHANISM OF STIMULATION OF ASCORBIC ACID SYNTHESIS BY DRUGS AND CARCINOGENIC HYDROCARBONS*

1961 • 27 citations

A study of the hormonal relations of epidermal mitotic activity in vitro *1III. Adrenalin

1955 • 26 citations

Durch Carcinogene Kohlenwasserstoffe und Geschlechtshormone in Gewebekulturen Erzielte Mitosestörungen

1939 • 26 citations

Effect of Vitamin C Deficiency on Action of Different Types of Barbiturates

1941 • 26 citations

The effects of ether on brain oxidations

1937 • 25 citations

THE EFFECTS OF URETHANE AND CHLORAL HYDRATE ON OXYGEN CONSUMPTION AND CELL DIVISION IN THE EGG OF THE SEA URCHIN, ARBACIA PUNCTULATA

1944 • 25 citations

The Cytotoxic Effect of Nitrous Oxide at Different Oxygen Tensions*).

1957 • 24 citations

The site of action of narcotics on brain metabolism.

1946 • 24 citations

CONSTITUTION AND C-MITOTIC ACTIVITY OF ISO-COLCHICINE

2010 • 24 citations

Some Effects of Methyl Cholanthrene on the Morphology and Growth of Yeasts

1937 • 23 citations

A Practice of Anaesthesia

1960 • 23 citations

Relationship of Time of Therapy to Teratogeny in Maternal Avitaminosis E

1953 • 23 citations

c-Mitotic Action of some Simple Gases

1950 • 22 citations

A COMPARISON OF THE EFFECTS OF NARCOTICS AND OF 2,4-DINITROPHENOL ON SULFANILAMIDE ACETYLATION

1953 • 22 citations

Extrafusal muscle and muscle spindles in reptiles

1974 • 22 citations

The effect of colchicine on the acid-soluble ribonucleotides of normal and regenerating rat liver

1963 • 22 citations

THE EFFECTS OF SOME HORMONES ON DEVELOPMENT

1952 • 21 citations

Croonian Lecture:—The laws of muscular motion

1926 • 21 citations

Artificial Production of Monstrosities in the Rabbit

1944 • 20 citations

Inhibition of Synthesis of RNA in E. coli by the Narcotic Drug Lævorphanol

1963 • 19 citations

The Mechanism of Cell-division A Study with Carbon Monoxide on the Sea-Urchin Egg

1953 • 19 citations

[Congenital malformations of the face and of extremities caused by tetracycline].

1957 • 19 citations

The effects of chemotherapy and irradiation therapy on the differentiation of experimental tumors

1958 • 18 citations

Effect of Colchicine on Synthesis of Desoxyribonucleic Acid in Tissue Cultured Rat Fibroblasts.

1953 • 17 citations

Über die Isolierung einer Ascorbinsäure-abhängigen DPNH-Oxydase

1957 • 17 citations

Carbamates in the Chemotherapy of Leukemia. II. the Relationship Between Chemical Structure, Leukopenic Action, and Acute Toxicity of a Group of Urethan Derivatives<xref ref-type="fn" rid="fn1"><sup>2</sup></xref>

1948 • 17 citations

EFFECTS OF LOCAL ANESTHETICS ON SODIUM AND POTASSIUM IN HUMAN RED CELLS.

1965 • 16 citations

THE EFFECTS OF SODIUM AMYTAL ON THE METABOLISM

1934 • 16 citations

Studies of the cytochemistry of nucleoproteins

1964 • 16 citations

Certain effects of irradiation and chemotherapy on cellular division and differentiation.

1955 • 15 citations

THE EFFECT OF URETHANE ON THE CONSUMPTION OF OXYGEN AND THE RATE OF CELL DIVISION IN THE CILIATE TETRAHYMENA GELEII

1944 • 15 citations

Reversal of Insulin-Induced Hypoglycemia in Chick Embryos by Nicotinamide and -Ketoglutaric Acid.

1949 • 15 citations

Production of congenital abnormalities in mice by alloxan.

1952 • 14 citations

A mammalian and protozoan electron-transport inhibitor in Tetrahymena pyriformis

1959 • 14 citations

THE EFFECT OF URETHANE ON THE NUCLEAR MORPHOLOGY OF CELLS OF THE GRANULOCYTE SERIES AS OBSERVED IN MARROW CULTURES AND LEUKEMIC BLOOD

1948 • 13 citations

Effects of Anesthetics, Depressants, and Tranquilizers on Cerebral Metabolism

1963 • 12 citations

Zur Kenntnis der Mitose V.

1938 • 12 citations

EFFECT OF COLCHICINE ON THE DEVELOPMENT OF THE FISH EMBRYO, ORYZIAS LATIPES

1940 • 11 citations

[Congenital malformations of the extremities induced experimentally in rat embryos by treatment with penicillin and streptomycin].

1957 • 11 citations

Chemical Prerequisites for Cell Division

1963 • 11 citations

[Effects of vitamin deficiency on fertility, pregnancy and progeny].

1954 • 11 citations

Über Synergisten von Mitosegiften. III. Mitteilung.

1951 • 11 citations

Inhibition of the Carcinogenic Properties of Urethane by Pentose Nucleotides

1949 • 11 citations

Das Schlafmittel Natrium-Pentobarbital: Ein rasch wirkendes Mitosegift im M�useversuch

1963 • 10 citations

Effects of Vitamin C Deficiency and Starvation upon the Toxicity of Procaine.*

1947 • 10 citations

Thalidomide: Effects on Ehrlich Ascites Tumor Cells in vitro

1964 • 10 citations

Action of Chloretone on Reduced Cozymaze Oxidation by Cytochrome c

1962 • 9 citations

The action of various drugs on certain phases of in vitro anabolism.

1950 • 9 citations

Effect of epinephrine, insulin, and tolbutamide on carbohydrate metabolism during ether anesthesia.

1960 • 9 citations

Chemical Aspects of the Isolated Mitotic Apparatus

1963 • 7 citations

The Site of Action of Narcotics on Brain Metabolism

1947 • 7 citations

The Influence of Colchicine on the Rate of Viscosity Drop in ATP‐Actomyosin‐Mixtures

1952 • 7 citations

Über Synergisten von Mitosegiften. VII. Mitteilung. Weitere Alkaloide und Colchicin oder N-Methyl-colchicamid

1951 • 6 citations

Some Embryological Aspects of Vitamin C-Deficiency in the Guinea Pig (Cavia Cobaya)

1951 • 6 citations

SOME EFFECTS OF COLCHICINE ON HEREDITY IN DAPHNIA LONGISPINA

1940 • 6 citations

Alleviation of mitotic poisoning by glucose

1950 • 6 citations

Potentiation of several hypnotic and anesthetic agents by colchicine.

1957 • 5 citations

Ascorbic acid analog in experimental cancer.

1953 • 5 citations

Die Zellteilung w�hrend und nach der Narkose

1931 • 5 citations

STUDIES OF FATTY ACID OXIDATION: 4. THE EFFECTS OF FATTY ACIDS ON THE OXIDATION OF OTHER METABOLITES

1956 • 5 citations

THE EFFECT OF PODOPHYLLOTOXIN, COLCHICINE, URETHANE, AND NITROGEN MUSTARD ON THE RESPIRATION OF NORMAL AND SUPRARENALECTOMIZED RAT LYMPHATIC TISSUE

1950 • 5 citations

EFFECT OF SOME DRUGS ON THE POLARIZATION STATE OF SPINAL CORD ELEMENTS

1950 • 5 citations

Ascorbic acid analog in experimental leukemia.

1954 • 4 citations

Uptake of potassium by erythrocytes in relation to their glucose consumption

1959 • 4 citations

Certain Effects of Irradiation, Nitrogen Mustard, Urethane and Colchicine on the Testis

1961 • 4 citations

Colchicine. II. Metabolism of frog skeletal muscle.

1953 • 4 citations

Recherches sur la respiration de la cellule vivante

1938 • 3 citations

The influence of urethanes on the enzymic activity of normal and malignant tissues.

1951 • 2 citations

THE EFFECT OF ANESTHETIC AGENTS ON CELLULAR MEMBRANES

1964 • 2 citations

Contractility

1963 • 1 citations

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THE EFFECT OF CNS DEPRESSANTS ON MITOSIS (1966) – Acta Anaesthesiologica Scandinavica | Metascience Observatory Explorer