Losses of Chromosomes 1p and 3q Are Early Genetic Events in the Development of Sporadic Pheochromocytomas

Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene

1993 • 2,906 citations

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A

1993 • 1,941 citations

Cloning of human satellite III DNA: different components are on different chromosomes

1979 • 470 citations

Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: correlation with N-myc amplification.

1989 • 395 citations

Identification of intragenic mutations in the Von Hippel — Lindau disease tumour suppressor gene andcorrelation with disease phenotype

1994 • 386 citations

Marked genetic differences between stage pTa and stage pT1 papillary bladder cancer detected by comparative genomic hybridization.

1997 • 250 citations

Specific Genetic Change in Tumors Associated With von Hippel-Lindau Disease

1989 • 222 citations

Deletions involving two distinct regions of 6q in B-cell non-Hodgkin lymphoma

1992 • 182 citations

Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas.

1995 • 171 citations

Genetic Differences in Endocrine Pancreatic Tumor Subtypes Detected by Comparative Genomic Hybridization

1999 • 166 citations

Malignant pheochromocytoma: Clinical, biological, histologic and therapeutic data in a series of 20 patients with distant metastases

1992 • 163 citations

Deletions involving two distinct regions of 6q in B-cell non-Hodgkin lymphoma

1992 • 145 citations

Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas.

1991 • 140 citations

Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis.

1992 • 131 citations

Consistent association of 1p loss of heterozygosity with pheochromocytomas from patients with multiple endocrine neoplasia type 2 syndromes.

1992 • 118 citations

A hypervariable repeated sequence on human chromosome 1p36

1987 • 114 citations

Neurofibromatosis and Cancer

1986 • 113 citations

Characterization of a cloned DNA sequence that is present at centromeres of all human autosomes and the X chromosome and shows polymorphic variation.

1984 • 107 citations

Analysis of Genomic Alterations in Sporadic Adrenocortical Lesions

1999 • 105 citations

MEN1 Gene mutation analysis of sporadic adrenocortical lesions

1999 • 98 citations

Von Hippel‐Lindau Syndrome

1995 • 94 citations

Germline mutations in thevhl gene in patients presenting with phaeochromocytomas

1998 • 88 citations

Comparative genomic hybridization analysis of sporadic neuroendocrine tumors of the digestive system

1998 • 87 citations

Prognostic significance of allelic losses in primary melanoma

1998 • 86 citations

Molecular genetic analysis of von Hippel–Lindau disease

1998 • 84 citations

Localization of a novel tumor suppressor locus on human chromosome 3q important in osteosarcoma tumorigenesis.

1997 • 80 citations

Prognostic value of p53, bcl-2, and c-erbB-2 protein expression in phaeochromocytomas

1999 • 73 citations

Acquired Homozygosity (Isodisomy) of Chromosome 3 in Uveal Melanoma

1998 • 71 citations

The Men II Syndromes and the Role of the ret Proto-oncogene

1996 • 68 citations

Loss of heterozygosity on the short arm of chromosomes 1 and 3 in sporadic pheochromocytoma and extra-adrenal paraganglioma

1997 • 64 citations

Von Hippel Lindau Syndrome

2010 • 62 citations

Chromosome specificity of satellite DNAs: short- and long-range organization of a diverged dimeric subset of human alpha satellite from chromosome 3

1989 • 62 citations

Loss of neurofibromatosis type I (NFI) gene expression in pheochromocytomas from patients without NFI

1995 • 59 citations

Loss of heterozygosity analysis defines a critical region in chromosome 1p22 commonly deleted in human malignant mesothelioma.

1996 • 53 citations

Loss of heterozygosity on the long arm of chromosome 22 in pheochromocytoma

1992 • 49 citations

Multiple regions of allelic loss from chromosome arm 6q in malignant mesothelioma.

1997 • 47 citations

Prognostic value ofRET proto-oncogene point mutations in malignant and benign, sporadic phaeochromocytomas

1998 • 45 citations

Absence ofTP53 alterations in pheochromocytomas and medullary thyroid carcinomas

1997 • 44 citations

Isolation and characterization of a novel human pancreas-specific gene,pancpin, that is down-regulated in pancreatic cancer cells

1998 • 43 citations

The relatively high frequency of p53 gene mutations in multiple and malignant phaeochromocytomas

1998 • 41 citations

Loss of Heterozygosity on Chromosomes 1p and 11p in Sporadic Pheochromocytoma

1989 • 38 citations

Isolation and mapping of 68 RFLP markers on human chromosome 6.

1992 • 32 citations

Neurofibromatosis gene cloned

1990 • 32 citations

Deletion mapping on the distal third region of chromosome 1p in multiple endocrine neoplasia type IIA.

1990 • 31 citations

Expression and prognostic value of c‐erbB‐2 oncogene product in human phaeochromocytomas

1997 • 28 citations

Expression patterns of the c-myc gene in adrenocortical tumors and pheochromocytomas

1997 • 25 citations

Deletion analysis of the p16 tumour suppressor gene in phaeochromocytomas

1996 • 22 citations

Von Hippel-Lindau Syndrome

1994 • 20 citations

Expression of c-fosand c-mycProto-Oncogenes in Human Adrenal Pheochromocytomas*

1990 • 20 citations

Mutation analysis of the c-mos proto-oncogene and the endothelin-B receptor gene in medullary thyroid carcinoma and phaeochromocytoma

1996 • 14 citations