In vivo dynamics of CD4^–8^– thymocytes. Proliferation, renewal and differentiation of different cell subsets studied by DNA biosynthetic labeling and surface antigen detection

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine.

1983 • 978 citations

IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement.

1980 • 835 citations

Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells

1985 • 613 citations

A monoclonal antibody discriminating between subsets of T and B cells.

1981 • 565 citations

A novel population of T-cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family

1987 • 397 citations

The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.

1984 • 389 citations

Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues

1982 • 359 citations

Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells.

1985 • 305 citations

Characterization of murine thymocytes with CDS-associated T-cell receptor structures

1987 • 245 citations

Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes.

1987 • 230 citations

Expression and functional significance of the J11d marker on mouse thymocytes.

1987 • 218 citations

Expression and function of interleukin-2 receptors on immature thymocytes

1985 • 217 citations

A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations

1985 • 199 citations

Quantitation of 5-bromo-2-deoxyuridine incorporation into DNA: an enzyme immunoassay for the assessment of the lymphoid cell proliferative response

1985 • 194 citations

Dynamics of Early T Cells: Prothymocyte Migration and Proliferation in the Adult Mouse Thymus

1986 • 188 citations

Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors.

1986 • 188 citations

Differentiation potential of subsets of CD4−8− thymocytes

1987 • 169 citations

Hematopoietic thymocyte precursors. I. Assay and kinetics of the appearance of progeny.

1976 • 154 citations

Bone marrow cells give rise to distinct cell clones within the thymus

1984 • 146 citations

The differentiation of T lymphocytes. V. Evidence for intrathymic death of most thymocytes.

1979 • 126 citations

In vivo thymocyte maturation. BUdR labeling of cycling thymocytes and phenotypic analysis of their progeny support the single lineage model.

1986 • 124 citations

Transient expression of IL-2 receptor precedes the differentiation of immature thymocytes

1987 • 112 citations

Absence of growth by most receptor-expressing fetal thymocytes in the presence of interleukin-2

1985 • 108 citations

Sequential events in thymocyte differentiation and thymus regeneration revealed by a combination of bromodeoxyuridine DNA labeling and antimitotic drug treatment.

1988 • 107 citations

Identification of early stages of T lymphocyte development in the thymus cortex and medulla.

1985 • 103 citations

Renewal and fate in the mammalian thymus: Mechanisms and inferences of thymocytokinetics

1972 • 99 citations

Cellular Traffic of the Thymus: Experiments with Chromosome Markers: Evidence from Parabiosis for an Afferent Stream of Cells

1964 • 92 citations

Recognition and Regulation in Cell-Mediated Immunity

1985 • 79 citations

An in vivo assay for thymus-homing bone marrow cells

1981 • 79 citations

Phenotypic properties, interleukin 2 production, and developmental origin of a "mature" subpopulation of Lyt-2- L3T4- mouse thymocytes.

1987 • 76 citations

Flow microfluorometric analysis of mouse thymus development in vivo and in vitro

1983 • 71 citations

The Lyt‐2, Lyt‐3 Macromolecules: Structural and Functional Studies

1982 • 64 citations

Heterogeneity of immature (Lyt-2-/L3T4-) thymocytes. Identification of four major phenotypically distinct subsets differing in cell cycle status and in vitro activation requirements.

1988 • 57 citations

Expression of interleukin 2 receptor on murine fetal thymocytes

1985 • 53 citations

Mucosal Immunity: IgA and Polymorphonuclear Neutrophils

1986 • 47 citations

Post‐Irradiation Thymocyte Regeneration After Bone Marrow Transplantation I. Regeneration and Quantification of Thymocyte Progenitor Cells In the Bone Marrow

1981 • 47 citations

Progenitor cells in the thymus: Most thymus-homing progenitor cells in the adult mouse thymus bear Pgp-1 glycoprotein but not interleukin-2 receptor on their cell surface

1986 • 44 citations

Expression of T cell antigen receptor beta-chains on subsets of mouse thymocytes. Analysis by three-color flow cytometry.

1987 • 42 citations

Localization and phenotype of cycling and post-cycling murine thymocytes studied by simultaneous detection of bromodeoxyuridine and surface antigens.

1988 • 42 citations

Expression of Pgp‐1 (or Ly24) by subpopulations of mouse thymocytes and activated peripheral T lymphocytes

1987 • 38 citations

Control of prothymocyte proliferation by thymic accessory cells

1987 • 35 citations

Subpopulations of CD4-CD8-murine thymocytes: differences in proliferation rate in vivo and proliferative responses in vitro

1988 • 32 citations

Ly-24 (Pgp-1) expression by thymocytes and peripheral T cells

1988 • 30 citations

Regulation of thymocyte proliferation and survival by deoxynucleosides. Deoxycytidine produced by thymic accessory cells protects thymocytes from deoxyguanosine toxicity and stimulates their spontaneous proliferation

1986 • 29 citations

Identification of intrathymic T progenitor cells by expression of Thy‐1, IL 2 receptor and CD3

1987 • 27 citations

Thymocytes with the predicted properties of pre-T cells.

1987 • 19 citations

Activation of T cell antigen receptor alpha- and beta-chain genes in the thymus: implications for the lineages of developing cortical thymocytes.

1986 • 16 citations

IL 2 Receptor Expression on Differentiating Lymphocytes in the Murine Thymocyte

1986 • 10 citations

In vivo proliferation and differentiation of prothymocytes in the thymus

1987 • 7 citations