Rapid and Specific Efflux of Reduced Glutathione during Apoptosis Induced by Anti-Fas/APO-1 Antibody

Glutathione S-Transferases

1974 • 17,321 citations

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

GLUTATHIONE

1983 • 5,487 citations

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1995 • 4,003 citations

Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1995 • 2,402 citations

Oxidative stress as a mediator of apoptosis

1994 • 2,210 citations

Protease activation during apoptosis: Death by a thousand cuts?

1995 • 1,335 citations

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

1995 • 983 citations

Involvement of an ICE-like protease in Fas-mediated apoptosis

1995 • 757 citations

FAP-1: A Protein Tyrosine Phosphatase That Associates with Fas

1995 • 702 citations

Programmed cell death and Bcl-2 protection in very low oxygen

1995 • 638 citations

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1994 • 621 citations

Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

1995 • 616 citations

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL

1995 • 611 citations

Fas- and Tumor Necrosis Factor-induced Apoptosis Is Inhibited by the Poxvirus crmA Gene Product

1995 • 604 citations

High-performance liquid chromatography of thiols and disulfides: Dinitrophenol derivatives

1987 • 504 citations

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

1995 • 501 citations

CPP32/Apopain Is a Key Interleukin 1β Converting Enzyme-like Protease Involved in Fas-mediated Apoptosis

1996 • 480 citations

Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation.

1993 • 419 citations

Glutathione deficiency and human immunodeficiency virus infection

1992 • 409 citations

HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state.

1995 • 386 citations

Glutathione : metabolism and physiological functions

1990 • 376 citations

Low Concentrations of Acid-Soluble Thiol (Cysteine) in the Blood Plasma of HIV-1-Infected Patients

1989 • 349 citations

The role of intracellular oxidants in apoptosis

1995 • 294 citations

Dithiocarbamates Induce Apoptosis in Thymocytes by Raising the Intracellular Level of Redox-active Copper

1995 • 280 citations

Formation and reduction of glutathione-protein mixed disulfides during oxidative stress

1987 • 267 citations

Methodologies for the application of monobromobimane to the simultaneous analysis of soluble and protein thiol components of biological systems

1986 • 235 citations

Glutathione export by human lymphoid cells: depletion of glutathione by inhibition of its synthesis decreases export and increases sensitivity to irradiation.

1981 • 230 citations

Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells.

1993 • 212 citations

Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor-dependent cytotoxicity on U937 cells.

1991 • 201 citations

Non-oxidative Loss of Glutathione in Apoptosis via GSH Extrusion

1995 • 190 citations

Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis

1995 • 189 citations

Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis.

1994 • 184 citations

P1 Aspartate-Based Peptide .alpha.-((2,6-Dichlorobenzoyl)oxy)methyl Ketones as Potent Time-Dependent Inhibitors of Interleukin-1.beta.-Converting Enzyme

1994 • 147 citations

A direct assessment of the importance of conjugation for biliary transport of sulfobromophthalein sodium.

1970 • 147 citations

Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling.

1995 • 142 citations

A decrease in intracellular glutathione concentration precedes the onset of apoptosis in murine thymocytes.

1995 • 125 citations

Transport of glutathione diethyl ester into human cells.

1993 • 118 citations

No requirement of reactive oxygen intermediates in Fas‐mediated apoptosis

1994 • 107 citations

Cellular Events in Fas/APO-1-Mediated Apoptosis in JURKAT T Lymphocytes

1995 • 105 citations

Identification and characterization of high and low affinity transport systems for reduced glutathione in liver cell canalicular membranes.

1994 • 84 citations

Translocation of glutathione from lymphoid cells that have markedly different gamma-glutamyl transpeptidase activities.

1979 • 73 citations

Protein-specific S-thiolation in human endothelial cells during oxidative stress

1992 • 69 citations

Evidence That the Rat Hepatic Mitochondrial Carrier Is Distinct from the Sinusoidal and Canalicular Transporters for Reduced Glutathione

1995 • 59 citations

Expression cloning of a rat hepatic reduced glutathione transporter with canalicular characteristics.

1994 • 49 citations

Does apoptosis contribute to CD4 T cell depletion in human immunodeficiency virus infection ?

1995 • 43 citations

Expression cloning of the cDNA for a polypeptide associated with rat hepatic sinusoidal reduced glutathione transport: characteristics and comparison with the canalicular transporter.

1995 • 37 citations

Expression of rat liver reduced glutathione transport in Xenopus laevis oocytes.

1993 • 31 citations

External Ca effect on water permeability, regulatory volume decrease, and extracellular space in barnacle muscle cells

1993 • 24 citations

Programmed cell death and AIDS: significance, perspectives and unanswered questions.

1995 • 23 citations

Quantitative Aspects of the Feeder Cell Phenomenon: Direct Assessment of Enhanced Cystine Uptake by Lymphocytes

1989 • 4 citations