Histopathological criteria and selection algorithms for BRCA1 genetic testing

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

2005 • 6,083 citations

Repeated observation of breast tumor subtypes in independent gene expression data sets

2003 • 5,356 citations

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

2005 • 4,715 citations

Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2

2003 • 2,170 citations

Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer

2003 • 938 citations

Triple negative tumours: a critical review

2007 • 870 citations

The Pathology of Familial Breast Cancer: Predictive Value of Immunohistochemical Markers Estrogen Receptor, Progesterone Receptor, HER-2, and p53 in Patients With Mutations in BRCA1 and BRCA2

2002 • 809 citations

Prediction of BRCA1 Status in Patients with Breast Cancer Using Estrogen Receptor and Basal Phenotype

2005 • 610 citations

Basal-like breast cancer and the BRCA1 phenotype

2006 • 463 citations

Hereditary breast cancer: Pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage

1996 • 463 citations

Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Recommendation Statement

2005 • 404 citations

Tumour biological features of BRCA1-induced breast and ovarian cancer

1997 • 346 citations

Estrogen Receptor Status in BRCA1 - and BRCA2 -Related Breast Cancer

2004 • 283 citations

Society of Gynecologic Oncologists Education Committee Statement on Risk Assessment for Inherited Gynecologic Cancer Predispositions☆

2007 • 253 citations

Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population

2001 • 209 citations

Limited Family Structure and BRCA Gene Mutation Status in Single Cases of Breast Cancer

2007 • 195 citations

Risk Assessment and Genetic Counseling for Hereditary Breast and Ovarian Cancer: Recommendations of the National Society of Genetic Counselors

2007 • 193 citations

Steroid receptors in hereditary breast carcinomas associated with BRCA1 or BRCA2 mutations or unknown susceptibility genes

1998 • 185 citations

The molecular pathology of hereditary breast cancer: genetic testing and therapeutic implications

2005 • 182 citations

Pretest Prediction of BRCA1 or BRCA2 Mutation by Risk Counselors and the Computer Model BRCAPRO

2002 • 151 citations

Recommendations for medical management of hereditary breast and ovarian cancer: The French National Ad Hoc Committee

1998 • 136 citations

Optimal Selection of Individuals for BRCA Mutation Testing: A Comparison of Available Methods

2006 • 119 citations

Genetic epidemiology of BRCA mutations – family history detects less than 50% of the mutation carriers

2007 • 118 citations

Histopathological features of breast tumours in BRCA1, BRCA2 and mutation-negative breast cancer families

2004 • 104 citations

Genetic susceptibility to breast cancer

2007 • 102 citations

Inherited BRCA2 mutation associated with high grade breast cancer

1998 • 98 citations

Distinction between hereditary and sporadic breast cancer on the basis of clinicopathological data

2006 • 96 citations

Clinicopathologic analysis of BRCA1- or BRCA2-associated hereditary breast carcinoma in Japanese women

1999 • 95 citations

Major improvement in the efficacy of BRCA1 mutation screening using morphoclinical features of breast cancer.

2000 • 84 citations

Brca2 hereditary breast cancer pathophenotype

1997 • 78 citations

The pathology of familial breast cancer: Immunohistochemistry and molecular analysis

1999 • 69 citations

The pathology of inherited breast cancer

2002 • 61 citations

Morphology of Breast Cancer as a Means of Triage of Patients for BRCA1 Genetic Testing

2006 • 44 citations

Comparison between genotype and phenotype identifies a high-risk population carryingBRCA1 mutations

2000 • 34 citations

Pathological features and BRCA1 mutation screening in premenopausal breast cancer patients.

2001 • 33 citations

Beratung, Genetische Testung und Prävention von Frauen mit einer familiären Belastung für das Mamma- und Ovarialkarzinom

2003 • 25 citations

Hereditary Breast Cancer: Part II. Management of Hereditary Breast Cancer: Implications of Molecular Genetics and Pathology

2008 • 19 citations

The pathology of familial breast cancer: Clinical and geneticcounselling implications of breast cancer pathology

1999 • 13 citations