The Biological Role of Truncated Insulin‐like Growth Factor‐1 and the Tripeptide GPE in the Central Nervous Systema

Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: Comparison with insulin-like growth factors I and II

1992 • 370 citations

Transient IGF-I gene expression during the maturation of functionally related central projection neurons

1991 • 287 citations

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes

1989 • 254 citations

Insulin-like growth factor I gene expression is induced in astrocytes during experimental demyelination.

1992 • 223 citations

Evolution of the insulin superfamily: cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus.

1990 • 192 citations

Characterization of somatomedins from human fetal brain: identification of a variant form of insulin-like growth factor I.

1986 • 166 citations

Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1

1989 • 154 citations

Insulin-like growth factor I mRNA levels are developmentally regulated in specific regions of the rat brain

1991 • 151 citations

Expression of IGF-I and -II mRNA in the brain and craniofacial region of the rat fetus

1991 • 146 citations

Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation.

1991 • 141 citations

Insulin-like growth factor 1 (IGF-1) receptors in the human brain: quantitative autoradiographic localization

1989 • 122 citations

Purification and partial sequence analysis of insulin-like growth factor-1 from bovine colostrum

1986 • 113 citations

Identification of Gly-Pro-Glu (GPE), the aminoterminal tripeptide of insulin-like growth factor 1 which is truncated in brain, as a novel neuroactive peptide

1989 • 110 citations

A comparison of the biological activity of the recombinant intact and truncated insulin-like growth factor 1 (IGF-1)

1989 • 101 citations

Isolation and characterization of variant IGF‐1 as well as IGF‐2 from adult human brain

1986 • 97 citations

Evolution of the insulin gene superfamily. Sequence of a preproinsulin-like growth factor cDNA from the Atlantic hagfish

1991 • 95 citations

Human platelet-derived mitogens. II. Subcellular localization of insulinlike growth factor I to the alpha-granule and release in response to thrombin

1989 • 93 citations

Insulin-like growth factor 1 stimulates the release of acetylcholine from rat cortical slices

1988 • 90 citations

Glycine modulation of NMDA-evoked release of [3H]acetylcholine and [3H]dopamine from rat striatal slices

1989 • 87 citations

Human embryonic somatomedin.

1981 • 81 citations

Effects of full-length and truncated insulin-like growth factor-I on nitrogen balance and muscle protein metabolism in nitrogen-restricted rats

1991 • 77 citations

Identification of IGF-1 receptors in primitive vertebrates

1993 • 70 citations

A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide

1989 • 70 citations

Classification of the insulin-like growth factor binding proteins into three distinct categories according to their binding specificities

1988 • 70 citations

Plasma clearance and tissue distribution of labelled insulin-like growth factor-I (IGF-I), IGF-II and des(1–3)IGF-I in rats

1991 • 67 citations

Human platelet-derived mitogens. I. Identification of insulinlike growth factors I and II by purification and N alpha amino acid sequence analysis

1989 • 53 citations

Fetal Bin Growth: Selective Action by Growth Hormone

1974 • 47 citations

Truncated IGF-1 exerts trophic effects on fetal brain tissue grafts

1990 • 44 citations

Prenatal action of growth hormone on brain and behaviour

1974 • 41 citations

Identification and purification of truncated insulin-like growth factor I from porcine uterus. Evidence for high biological potency

1989 • 38 citations

Growth factors—from genes to clinical application

1991 • 31 citations

Enhanced potency of truncated insulin-like growth factor-I (des(1–3)IGF-I) relative to IGF-I in lit/lit mice

1990 • 30 citations

Studies on the Effect of Insulin‐Like Growth Factor‐I on Catecholamine Secretion from Chromaffin Cells

1990 • 28 citations

Occurrence of members of the insulin superfamily in central nervous system and digestive tract of protochordates

1993 • 24 citations

Presence of IGF-1-like peptides in the neuroendocrine system of the Atlantic Hagfish, Myxine glutinosa (Cyclostomata): evidence derived by chromatography, radioimmunoassay and immunohistochemistry

1991 • 22 citations

Hormonal Regulation of Fetal Brain Cell Proliferation: Presence in Serum of a Trophin Responsive to Pituitary Growth Hormone Stimulation

1976 • 19 citations

Circulating forms and biological activity of intact and truncated insulin-like growth factor I in adult and neonatal rats

1990 • 16 citations

Characterization of two cDNAs encoding insulin-like growth factor 1 (IGF-1) in the human fetal brain

1992 • 8 citations

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