Inhibition of lymphoma invasion and liver metastasis formation by pertussis toxin.

G Proteins: A Family of Signal Transducers

1986 • 975 citations

Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein.

1982 • 808 citations

Tumor cell autocrine motility factor.

1986 • 539 citations

Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells.

1986 • 424 citations

Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin

1984 • 418 citations

Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production

1986 • 406 citations

ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing biosignaling.

1984 • 389 citations

Two guanine nucleotide-binding proteins in rat brain serving as the specific substrate of islet-activating protein, pertussis toxin. Interaction of the alpha-subunits with beta gamma-subunits in development of their biological activities.

1986 • 315 citations

Stimulation and inhibition of adenylyl cyclases mediated by distinct regulatory proteins

1983 • 309 citations

Chemoattractant Receptors on Phagocytic Cells

1984 • 236 citations

Thyrotropin-releasing hormone activates a Ca2+-dependent polyphosphoinositide phosphodiesterase in permeable GH3 cells. GTP gamma S potentiation by a cholera and pertussis toxin-insensitive mechanism.

1986 • 197 citations

Pertussis toxin inhibition of chemotactic factor-induced calcium mobilization and function in human polymorphonuclear leukocytes.

1985 • 192 citations

Inhibition of lymphocyte and neutrophil chemotaxis by pertussis toxin.

1985 • 189 citations

Tumor metastases and cell‐mediated immunity in a model system in DBA/2 mice. I. Tumor invasiveness in vitro and metastasis formation in vivo

1979 • 159 citations

Modulating Influence of Chemotactic Factor-Induced Cell Adhesiveness on Granulocyte Function

1979 • 151 citations

Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils.

1986 • 148 citations

Molecular mechanisms of lymphocyte extravasation. I. Studies of two selective inhibitors of lymphocyte recirculation.

1984 • 140 citations

Selection and Biologic Properties of Malignant Variants of a Murine Lymphosarcoma<xref ref-type="fn" rid="FN2">2</xref>

1978 • 138 citations

Cell surface sialic acid and the invasive and metastatic potential of T-cell hybridomas.

1986 • 121 citations

Coupling of the thyrotropin-releasing hormone receptor to phospholipase C by a GTP-binding protein distinct from the inhibitory or stimulatory GTP-binding protein.

1986 • 85 citations

A pertussis/choleratoxin-sensitive N protein may mediate chemoattractant receptor signal transduction

1986 • 74 citations

Pertussis toxin blocks angiotensin II‐induced calcium influx but not inositol trisphosphate production in adrenal glomerulosa cell

1986 • 74 citations

The role of cytosolic free calcium in the generation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in HL-60 cells. Differential effects of chemotactic peptide receptor stimulation at distinct Ca2+ levels.

1986 • 71 citations

Generation of invasive and metastatic variants of a non‐metastatic T‐cell lymphoma by in vivo fusion with normal host cells

1984 • 68 citations

Invasive and metastatic potential induced by ras-transfection into mouse BW5147 T-lymphoma cells.

1987 • 63 citations

Invasiveness of T-cell hybridomas in vitro and their metastatic potential in vivo.

1985 • 62 citations

Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h.

1986 • 55 citations

Infiltration of tumour cells into cultures of isolated hepatocytes

1981 • 54 citations

Involvement of leukocyte function-associated antigen-1 (LFA-1) in the invasion of hepatocyte cultures by lymphoma and T-cell hybridoma cells.

1987 • 53 citations

Invasion of Lymphosarcoma Cells Into the Perfused Mouse Liver

1977 • 50 citations

Bradykinin stimulates GTP hydrolysis in NG108‐15 membranes by a high‐affinity, pertussis toxin‐insensitive GTPase

1986 • 36 citations

Pertussis toxin does not prevent alpha adrenergic stimulated breakdown of phosphoinositides or respiration in brown adipocytes

1986 • 34 citations

Effect of tubulin-binding agents on the infiltration of tumour cells into primary hepatocyte cultures

1982 • 32 citations

Antigen-activated T lymphocytes infiltrate hepatocyte cultures in a manner comparable to liver-colonizing lymphosarcoma cells

1983 • 30 citations

Site-selective homing of antigen-primed lymphocyte populations can play a crucial role in the efferent limb of cell-mediated immune responses in vivo.

1985 • 27 citations