Oral Administration of Growth Hormone (GH) Releasing Peptide-Mimetic MK-677 Stimulates the GH/Insulin-Like Growth Factor-I Axis in Selected GH-Deficient Adults¹

A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

1996 • 2,048 citations

Effects of Human Growth Hormone in Men over 60 Years Old

1990 • 1,560 citations

Premature mortality due to cardiovascular disease in hypopituitarism

1990 • 1,424 citations

The Effects of Treatment with Recombinant Human Growth Hormone on Body Composition and Metabolism in Adults with Growth Hormone Deficiency

1989 • 1,411 citations

Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection

1986 • 888 citations

Somatomedin-C Mediates Growth Hormone Negative Feedback by Effects on Both the Hypothalamus and the Pituitary

1981 • 829 citations

On thein Vitroandin VivoActivity of a New Synthetic Hexapeptide that Acts on the Pituitary to Specifically Release Growth Hormone*

1984 • 652 citations

Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adults

1992 • 400 citations

Cardiovascular risk factors in adult patients with growth hormone deficiency

1993 • 354 citations

A Nonpeptidyl Growth Hormone Secretagogue

1993 • 345 citations

Growth Hormone (GH)-Releasing Peptide Stimulates GH Release in Normal Men and Acts Synergistically with GH-Releasing Hormone*

1990 • 315 citations

On the Actions of the Growth Hormone-Releasing Hexapeptide, GHRP*

1991 • 308 citations

Insulin-Like Growth Factor I Action on Rat Anterior Pituitary Cells: Suppression of Growth Hormone Secretion and Messenger Ribonucleic Acid Levels*

1986 • 265 citations

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects.

1996 • 256 citations

Serum lipid levels in growth hormone-deficient men

1994 • 208 citations

Effects of treatment with recombinant human growth hormone on insulin sensitivity and glucose metabolism in adults with growth hormone deficiency

1993 • 202 citations

Identification of a new G-protein-linked receptor for growth hormone secretagogues.

1996 • 199 citations

A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans.

1993 • 197 citations

Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP-6 main action is exerted at the hypothalamic level.

1995 • 189 citations

Enhanced sensitivity growth hormone (GH) chemiluminescence assay reveals lower postglucose nadir GH concentrations in men than women.

1994 • 184 citations

Systemic administration of growth hormone-releasing peptide activates hypothalamic arcuate neurons

1993 • 182 citations

Growth hormone (GH)-releasing hormone secretion is stimulated by a new GH-releasing hexapeptide in sheep.

1994 • 163 citations

Evidence for a Role of Protein Kinase-C in His-D-Trp Ala-Trp-D-Phe-Lys-NH₂-Induced Growth Hormone Release from Rat Primary Pituitary Cells

1991 • 136 citations

Identification of a new G-protein-linked receptor for growth hormone secretagogues

1996 • 131 citations

Central Actions of Peptide and Non-Peptide Growth Hormone Secretagogues in the Rat

1995 • 116 citations

EFFECT OF A NEW SYNTHETIC HEXAPEPTIDE TO SELECTIVELY STIMULATE GROWTH HORMONE RELEASE IN HEALTHY HUMAN SUBJECTS

1989 • 115 citations

Negative feedback regulation of pulsatile growth hormone secretion by insulin-like growth factor I. Involvement of hypothalamic somatostatin.

1994 • 111 citations

The growth hormone-releasing activity of a synthetic hexapeptide in normal men and short statured children after oral administration.

1992 • 110 citations

Maturation of the Regulation of Growth Hormone Secretion in Young Males with Hypogonadotropic Hypogonadism Pharmacologically Exposed to Progressive Increments in Serum Testosterone¹

1997 • 99 citations

Adrenergic neurons in human brain demonstrated by immunohistochemistry with antibodies to phenylethanolamine-N-methyltransferase (PNMT): Discovery of a new group in the nucleus tractus solitarius

1985 • 97 citations

Growth hormone response in man to L-692,429, a novel nonpeptide mimic of growth hormone-releasing peptide-6.

1993 • 97 citations

Effect of growth hormone (GH)-releasing hormone (GHRH), atropine, pyridostigmine, or hypoglycemia on GHRP-6-induced GH secretion in man.

1993 • 81 citations

Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP- 6 main action is exerted at the hypothalamic level

1995 • 79 citations

Enhanced sensitivity growth hormone (GH) chemiluminescence assay reveals lower postglucose nadir GH concentrations in men than women

1994 • 78 citations

Oral administration of growth hormone (GH)-releasing peptide stimulates GH secretion in normal men.

1992 • 75 citations

Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects.

1994 • 74 citations

Maturation of the Regulation of Growth Hormone Secretion in Young Males with Hypogonadotropic Hypogonadism Pharmacologically Exposed to Progressive Increments in Serum Testosterone

1997 • 69 citations

The growth hormone-releasing activity of a synthetic hexapeptide in normal men and short statured children after oral administration

1992 • 59 citations

The Growth Hormone Secretagogue, L-692,429, Induces Phosphatidylinositol Hydrolysis and Hormone Secretion by Human Pituitary Tumors

1995 • 58 citations

Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692,429, in older adults--a clinical research center study.

1996 • 54 citations

Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy. Geref International Study Group.

1996 • 52 citations

Repeat administration of the GH secretagogue MK-0677 increases and maintains elevated IGF-I levels in beagles

1997 • 48 citations

Growth hormone (GH)-releasing hormone secretion is stimulated by a new GH-releasing hexapeptide in sheep

1994 • 47 citations

Effect of growth hormone (GH)-releasing hormone (GHRH), atropine, pyridostigmine, or hypoglycemia on GHRP-6-induced GH secretion in man

1993 • 33 citations

Effects in vitro of New Growth Hormone Releasing Peptide (GHRP‐1) on Growth Hormone Secretion from Ovine Pituitary Cells in Primary Culture

1994 • 31 citations

Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692,429, in older adults--a clinical research center study

1996 • 31 citations

Subcutaneous growth hormone-releasing hormone therapy in growth hormone-deficient children: first year of therapy.

1992 • 15 citations

Subcutaneous growth hormone-releasing hormone therapy in growth hormone- deficient children: first year of therapy

1992 • 12 citations

Long Term Therapy with a Single Daily Subcutaneous Dose of Growth Hormone Releasing Hormone (1-29) in Prepubertal Growth Hormone Deficient Children

1994 • 8 citations

Diagnostic value of growth hormone-releasing hormone test in children and adolescents with idiopathic growth hormone deficiency

1992 • 7 citations