Bis induces growth inhibition and differentiation of HL-60 cells via up-regulation of p27

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1991 • 5,120 citations

G1 phase progression: Cycling on cue

1994 • 2,706 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.

1979 • 1,019 citations

Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity

1995 • 863 citations

An Evolutionarily Conserved Family of Hsp70/Hsc70 Molecular Chaperone Regulators

1999 • 509 citations

p21--Negative Regulator of the Cell Cycle

1996 • 396 citations

Cyclins, Cyclin-Dependent Kinases and Cdk Inhibitors: Implications in Cell Cycle Control and Cancer

1995 • 314 citations

bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells

1992 • 276 citations

Differential expression and cell cycle regulation of the cyclin-dependent kinase 4 inhibitor p16Ink4.

1994 • 231 citations

Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death

1999 • 194 citations

CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-γ and Hsp70/Hsc70

2000 • 148 citations

Regulation of Bcl-2 oncoprotein levels with differentiation of human neuroblastoma cells.

1993 • 144 citations

The anti‐apoptotic protein BAG‐3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines

2001 • 140 citations

Bcl2 inhibits apoptosis associated with terminal differentiation of HL- 60 myeloid leukemia cells

1994 • 136 citations

BCL2 regulates neural differentiation.

1996 • 131 citations

Dysregulated bcl-2 expression inhibits apoptosis but not differentiation of retinoic acid-induced HL-60 granulocytes

1994 • 99 citations

Expression of p21Cip1/Waf1/Sdi1 and p27Kip1Cyclin-Dependent Kinase Inhibitors During Human Hematopoiesis

1999 • 93 citations

The absence of p27Kip1, an inhibitor of G1 cyclin-dependent kinases, uncouples differentiation and growth arrest during the granulosa->luteal transition.

1998 • 81 citations

A PKC-η/Fyn-Dependent Pathway Leading to Keratinocyte Growth Arrest and Differentiation

2000 • 78 citations

Subcellular and Cell-Cycle Expression Profiles of CDK-Inhibitors in Normal Differentiating Myeloid Cells

1999 • 77 citations

Subcellular and Cell-Cycle Expression Profiles of CDK-Inhibitors in Normal Differentiating Myeloid Cells

1999 • 67 citations

Bag1 is a regulator and marker of neuronal differentiation

2002 • 67 citations

Identification of differentially expressed genes induced by transient ischemic stroke

2002 • 57 citations

bcl-2 gene expression in hematopoietic cell differentiation

1992 • 57 citations

Transforming growth factor-?1 is an autocrine mediator of U937 cell growth arrest and differentiation induced by vitamin D3 and retinoids

1999 • 57 citations

p27KIP1, an inhibitor of cyclin-dependent kinases

1995 • 52 citations

The myeloid zinc finger gene (MZF-1) delays retinoic acid-induced apoptosis and differentiation in myeloid leukemia cells

1998 • 49 citations

Reactive Astrocytes Express Bis, a Bcl-2-Binding Protein, after Transient Forebrain Ischemia

2002 • 45 citations

Apoptosis in Normal Rat Embryo Tissues during Early Organogenesis: The Possible Involvement of Bax and Bcl-2.

2002 • 39 citations

Induction of Bis, a Bcl-2-binding protein, in reactive astrocytes of the rat hippocampus following kainic acid-induced seizure

2002 • 38 citations

Bcl-2 accelerates the neuronal differentiation: new evidence approaching to the biofunction of Bcl-2 in the neuronal system

1998 • 37 citations

bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells

1992 • 37 citations

Possible Involvement of Bcl-2 Pathway in Retinoid X Receptor Alpha-Induced Apoptosis of HL-60 Cells

1997 • 37 citations

Growth arrest by octanoate is required for porcine preadipocyte differentiation

2003 • 33 citations

Bcl-2 mediates induction of neural differentiation

2003 • 29 citations

Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest

2000 • 28 citations

Bcl‐2 expression inversely correlates with tumour cell differentiation in medulloblastoma

2004 • 26 citations

Ectopic expression of Bcl-2 switches over nuclear signalling for cAMP-induced apoptosis to granulocytic differentiation

2000 • 22 citations

Increased resistance to apoptosis associated with HL-60 myeloid differentiation status.

1994 • 19 citations

Dysregulated bcl-2 expression inhibits apoptosis but not differentiation of retinoic acid-induced HL-60 granulocytes

1994 • 15 citations

Bcl2 inhibits apoptosis associated with terminal differentiation of HL- 60 myeloid leukemia cells

1994 • 14 citations

8-Cl-Adenosine Induces Growth Arrest without Differentiation of Primary Mouse Epidermal Keratinocytes

2001 • 12 citations

Implication of CDK Inhibitors p21 and p27 in the Differentiation of HL-60 Cells

2004 • 11 citations

Expression of p21Cip1/Waf1/Sdi1 and p27Kip1Cyclin-Dependent Kinase Inhibitors During Human Hematopoiesis

1999 • 10 citations

bcl-2 gene expression in hematopoietic cell differentiation

1992 • 8 citations

Bleomycin-induced differentiation of bcl-2-transfected U937 leukemia cells.

1996 • 8 citations

Apoptosis in normal rat embryo tissues during early organogenesis : The possible involvement of Bax and Bcl-2

2003 • 6 citations