Low Density Lipoprotein Binding and Uptake by Human and Rat Isletβ Cells*

A Receptor-Mediated Pathway for Cholesterol Homeostasis

1986 • 5,638 citations

Efficient Trace-labelling of Proteins with Iodine

1958 • 2,571 citations

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

The metabolism of very low density lipoprotein proteins I. Preliminary in vitro and in vivo observations

1972 • 1,831 citations

[19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1983 • 1,639 citations

Separation of plasma lipoproteins by density-gradient ultracentrifugation

1975 • 1,114 citations

Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications

1995 • 1,026 citations

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships.

1994 • 813 citations

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.

1994 • 683 citations

Inhibition of the Lysosomal Pathway of Protein Degradation in Isolated Rat Hepatocytes by Ammonia, Methylamine, Chloroquine and Leupeptin

1979 • 466 citations

Acetoacetylated lipoproteins used to distinguish fibroblasts from macrophages in vitro by fluorescence microscopy.

1981 • 396 citations

Interplay of Nutrients and Hormones in the Regulation of Insulin Release*

1985 • 363 citations

A New in Vitro Model for the Study of Pancreatic A and B Cells*

1985 • 345 citations

Pancreatic β-Cells in Obesity

1995 • 276 citations

Low-density lipoprotein receptor activity in cultured human skin fibroblasts. Mechanism of insulin-induced stimulation.

1979 • 245 citations

Pathogenesis of non-insulin-dependent diabetes mellitus

1994 • 239 citations

Rate and equilibrium constants for binding of apo-E HDL _c (a cholesterol-induced lipoprotein) and low density lipoproteins to human fibroblasts: Evidence for multiple receptor binding of apo-E HDL _c

1979 • 215 citations

Lipoprotein-receptor interactions

1986 • 191 citations

Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation.

1996 • 177 citations

Regulation of Adenosine 3′,5′-Monophosphate Levels in the Pancreatic B Cell*

1985 • 152 citations

In Vivo Stimulation of Low-Density Lipoprotein Degradation by Insulin

1984 • 121 citations

A method for the purification of single A, B and D cells and for the isolation of coupled cells from isolated rat islets

1981 • 112 citations

Plasma low density lipoprotein transport kinetics in noninsulin-dependent diabetes mellitus.

1983 • 81 citations

Saturable high affinity binding, uptake and degradation of rat plasma lipoproteins by isolated parenchymal and non-parenchymal cells from rat liver

1981 • 58 citations

Preservation of glucose-responsive islet beta-cells during serum-free culture.

1994 • 35 citations

Uptake and degradation of human low-density lipoprotein by human liver parenchymal and Kupffer cells in culture

1991 • 30 citations

Insulin and lipoprotein metabolism with special reference to the diabetic state

1994 • 24 citations

Dyslipidaemia and diabetes

2001 • 16 citations

Viscount Bledisloe of Lydney, G.C.M.G., K.B.E.

1958 • 12 citations

Complete down‐regulation of low‐density lipoprotein receptor activity in human liver parenchymal cells by β‐very‐low‐density lipoprotein

1991 • 7 citations