A Phase II study of high-dose tamoxifen in patients with hormone-refractory prostate cancer.

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Measuring the quality of life of cancer patients: the Functional Living Index-Cancer: development and validation.

1984 • 1,063 citations

The pharmacology and clinical uses of tamoxifen

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Phase II evaluation of oral estramustine and oral etoposide in hormone-refractory adenocarcinoma of the prostate.

1994 • 225 citations

High-Dose Oral Tamoxifen, a Potential Multidrug-Resistance-Reversal Agent: Phase I Trial in Combination With Vinblastine

1992 • 209 citations

Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells.

1996 • 195 citations

Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines

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Estimating the quality of life in a clinical trial of patients with metastatic lung cancer using the Karnofsky performance status and the functional living index—cancer

1988 • 188 citations

Genistein-Induced Apoptosis of Prostate Cancer Cells is Preceded by a Specific Decrease in Focal Adhesion Kinase Activity

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Loss of expression of transforming growth factor beta type I and type II receptors correlates with tumor grade in human prostate cancer tissues.

1996 • 167 citations

Tamoxifen-associated eye disease. A review.

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Clinical and Radiographic Response in a Minority of Patients with Recurrent Malignant Gliomas Treated with High-Dose Tamoxifen

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Triphenylethylenes: A New Class of Protein Kinase C Inhibitors

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Evaluation of Tamoxifen Doses With and Without Fluoxymesterone in Advanced Breast Cancer

1983 • 129 citations

Clinical Trials in Relapsed Prostate Cancer: Defining the Target

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Inhibition of Prostate Cancer Growth by Estramustineand Etoposide: Evidence For Interaction at the Nuclear Matrix

1993 • 103 citations

Confidence Limits for Probability of Response in Multistage Phase II Clinical Trials

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Evolving strategies of cytotoxic chemotherapy for advanced prostate cancer

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Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to beta-l-integrin

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1996 • 83 citations

HOW IS ANDROGEN-DEPENDENT METASTATIC PROSTATE CANCER BEST TREATED?

1996 • 73 citations

Different Signals Mediate Transforming Growth Factor-β1-Induced Growth Inhibition and Extracellular Matrix Production in Prostatic Carcinoma Cells

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Fenretinide: induction of apoptosis and endogenous transforming growth factor beta in PC-3 prostate cancer cells.

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Prostate cancer cell growth inhibition by tamoxifen is associated with inhibition of protein kinase C and induction of p21waf1/cip1

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Phase II trial of tamoxifen in metastatic carcinoma of the prostate

1982 • 35 citations

A phase II study of Nolvadex® tamoxifen citrate in the treatment of advanced prostatic adenocarcinoma

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Tamoxifen metabolic patterns within a glioma patient population treated with high‐dose tamoxifen

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A comparison of the relative chemosensitivity of human gliomas to tamoxifen and n-desmethyltamoxifenin vitro

1994 • 22 citations

Hormonal therapy for metastatic renal cell carcinoma combined androgen and provera followed by high dose tamoxifen

1993 • 20 citations

The Efficacy of Tamoxifen as an Antiproliferative Agent in vitro for Benign and Malignant Pediatric Glial Tumors

1995 • 19 citations

Targeted therapy for prostate cancer: the Memorial Sloan-Kettering Cancer Center approach.

1996 • 19 citations

Treatment of Metastatic Carcinoma of the Prostate

1997 • 16 citations

Paclitaxel and carboplatin for advanced breast cancer.

1996 • 15 citations

Prolonged treatment with biologic agents for malignant glioma: a case study with high dose tamoxifen.

1997 • 14 citations

Role of prostatic basal cells in the regulation and suppression of human prostate cancer cells

1996 • 12 citations

Clinical and radiographic stabilization of intracranial glioblastoma. Report of a case treated after surgery with tamoxifen.

1996 • 2 citations