Further characterization of the binding of human recombinant interleukin 2 to heparin and identification of putative binding sites

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1978 • 3,314 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation.

1988 • 810 citations

Heparin Structure and Interactions with Basic Fibroblast Growth Factor

1996 • 789 citations

The IL-2 Receptor Complex: Its Structure, Function, and Target Genes

1993 • 601 citations

Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.

1992 • 511 citations

Structure and function of heparan sulphate proteoglycans

1986 • 485 citations

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1995 • 478 citations

Cell surface heparan sulfate proteoglycans.

1992 • 476 citations

Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor.

1993 • 449 citations

N.m.r. and molecular-modelling studies of the solution conformation of heparin

1993 • 400 citations

Extension and structural variability of the antithrombin-binding sequence in heparin.

1984 • 340 citations

Energetic Characterization of the Basic Fibroblast Growth Factor-Heparin Interaction: Identification of the Heparin Binding Domain

1994 • 296 citations

Interleukin 2 and its receptors: recent advances and new immunological functions

1996 • 241 citations

Delineation of the glycosaminoglycan-binding site in the human inflammatory response protein lactoferrin.

1994 • 225 citations

Proteoglycans in haemopoietic cells

1990 • 192 citations

Structure-function analysis of human interleukin-2. Identification of amino acid residues required for biological activity.

1987 • 147 citations

Heparin Decreases the Blood Clearance of Interferon-γ and Increases Its Activity by Limiting the Processing of Its Carboxyl-terminal Sequence

1996 • 138 citations

Preparation of affinity-fractionated, heparin-derived oligosaccharides and their effects on selected biological activities mediated by basic fibroblast growth factor.

1993 • 138 citations

Glycosaminoglycan-protein interactions: a question of specificity

1994 • 129 citations

Selective and differential binding of interleukin (IL)‐1α, IL‐1β, IL‐2 and IL‐6 to glycosaminoglycans

1992 • 123 citations

Heparin with two binding sites for antithrombin or platelet factor 4.

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Structure‐function analysis of human interleukin‐6

1990 • 107 citations

Localization in human interleukin 2 of the binding site to the alpha chain (p55) of the interleukin 2 receptor.

1991 • 98 citations

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Molecular Analysis of the Interleukin‐2 System

1986 • 89 citations

Kinetic analysis of ligand binding to interleukin‐2 receptor complexes created on an optical biosensor surface

1996 • 87 citations

Anti-HIV-1 Activity of Chemically Modified Heparins: Correlation between Binding to the V3 Loop of gp120 and Inhibition of Cellular HIV-1 Infection in vitro

1994 • 72 citations

The interleukin-2 and interleukin-4 receptors studied by molecular modelling

1994 • 57 citations

Separation of radiolabelled glycosaminoglycan oligosaccharides by polyacrylamide-gel electrophoresis

1984 • 53 citations

Receptor antagonist and selective agonist derivatives of mouse interleukin-2.

1992 • 45 citations

The Solution Structure of the F42A Mutant of Human Interleukin 2

1995 • 42 citations

Structural and Biologic Properties of a Human Aspartic Acid-126 Interleukin-2 Analog

1993 • 27 citations

Structural analogs of interleukin-2: a point mutation that facilitates biological response.

1995 • 10 citations

Analysis of Glycosaminoglycans and Proteoglycans

2003 • 9 citations

Characterization of a monoclonal antibody directed against the NH2 terminal area of interleukin-2 (IL-2) and inhibiting specifically the binding of IL-2 to IL-2 receptor β chain (IL-2Rβ)

1995 • 8 citations

Immunochemical characterization of antigenic domains on human IL-2: Spatially distinct epitopes are associated with binding to the p55 and p70 subunits of IL-2 receptor

1992 • 7 citations