Towards the prevention of neural tube defects

Maternal serum screening for Down's syndrome in early pregnancy.

1988 • 972 citations

An association between low maternal serum α-fetoprotein and fetal chromosomal abnormalities

1984 • 743 citations

ALPHA-FETOPROTEIN IN THE ANTENATAL DIAGNOSIS OF ANENCEPHALY AND SPINA BIFIDA

1972 • 603 citations

FURTHER EXPERIENCE OF VITAMIN SUPPLEMENTATION FOR PREVENTION OF NEURAL TUBE DEFECT RECURRENCES

1983 • 504 citations

MATERNAL SERUM ALPHA-FETOPROTEIN MEASUREMENT: A SCREENING TEST FOR DOWN SYNDROME

1984 • 425 citations

Apparent prevention of neural tube defects by periconceptional vitamin supplementation.

1981 • 389 citations

PRENATAL DIAGNOSIS OF ANENCEPHALY THROUGH MATERNAL SERUM-ALPHAFETOPROTEIN MEASUREMENT

1973 • 201 citations

AMNIOTIC-FLUID ACETYLCHOLINESTERASE AS A POSSIBLE DIAGNOSTIC TEST FOR NEURAL-TUBE DEFECTS IN EARLY PREGNANCY

1979 • 185 citations

MATERNAL SERUM-ALPHA-FETOPROTEIN MEASUREMENT IN ANTENATAL SCREENING FOR ANENCEPHALY AND SPINA BIFIDA IN EARLY PREGNANCY

1977 • 155 citations

PRENATAL DIAGNOSIS OF SPINA BIFIDA AND ANENCEPHALY THROUGH MATERNAL PLASMA-ALPHA-FETOPROTEIN MEASUREMENT

1974 • 111 citations

PRENATAL DIAGNOSIS OF SPINA BIFIDA AND ANENCEPHALY BY MATERNAL SERUM-ALPHA-FETOPROTEIN MEASUREMENT

1974 • 111 citations

Maternal Serum Alpha‐fetoprotein and Diabetes Mellitus

1981 • 95 citations

AVOIDANCE OF ANENCEPHALIC AND SPINA BIFIDA BIRTHS BY MATERNAL SERUM-ALPHAFETOPROTEIN SCREENING

1978 • 93 citations

Periconceptional vitamin supplementation and the prevention of neural tube defects in south-east England and Northern Ireland.

1984 • 92 citations

THE EFFECT OF MATERNAL WEIGHT ON MATERNAL SERUM ALPHA‐FETOPROTEIN LEVELS

1981 • 90 citations

Neural‐tube defects and vitamins: the need for a randomized clinical trial

1984 • 89 citations

SMALL BIPARIETAL DIAMETER OF FETUSES WITH SPINA BIFIDA: IMPLICATIONS FOR ANTENATAL SCREENING

1980 • 75 citations

Amniotic Fluid Acetylcholinesterase Electrophoresis as a Secondary Test in the Diagnosis of Anencephaly and Open Spina Bifida in Early Pregnancy

1982 • 62 citations

MATERNAL PLASMA ALPHA‐FETOPROTEIN SCREENING FOR FETAL NEURAL TUBE DEFECTS

1978 • 59 citations

Relation between maternal weight and serum alpha-fetoprotein concentration during the second trimester.

1981 • 58 citations

MECHANISMS BY WHICH AMNIOTIC-FLUID ALPHA-FETOPROTEIN MAY BE INCREASED IN FETAL ABNORMALITIES

1976 • 58 citations

Spina bifida and anencephaly in Scotland.

1984 • 57 citations

The impact of screening for open neural tube defects in England and Wales

1987 • 52 citations

ANTENATAL SCREENING IN OXFORD FOR FETAL NEURAL TUBE DEFECTS

1979 • 47 citations

Recurrent neural tube defects, risk factors and vitamins.

1986 • 43 citations

Estimating an individual's risk of having a fetus with open spina bifida and the value of repeat alpha-fetoprotein testing: FOURTH REPORT OF THE UK COLLABORATIVE STUDY ON ALPHA-FETOPROTEIN IN RELATION TO NEURAL TUBE DEFECTS

1982 • 38 citations

PRENATAL DIAGNOSIS OF NEURAL-TUBE DEFECTS WITH A MONOCLONAL ANTIBODY SPECIFIC FOR ACETYLCHOLINESTERASE

1985 • 27 citations

Quantitative enzyme antigen immunoassay of acetylcholinesterase in amniotic fluid.

1983 • 27 citations

AMNIOTIC-FLUID ALPHA-FETOPROTEIN MEASUREMENT IN ANTENATAL DIAGNOSIS OF ANENCEPHALY AND OPEN SPINA BIFIDA IN EARLY PREGNANCY

1979 • 27 citations

Immunochemical determination of acetylcholinesterase in amniotic fluid — An evaluation of eleven monoclonal antibodies

1987 • 21 citations

Maternal serum alpha‐fetoprotein and ethnic origin

1987 • 12 citations

Prospective prenatal screening for fetal abnormalities using a quantitative immunoassay for acetylcholinesterase.

1988 • 8 citations

Fetal Diagnosis of Genetic Defects

1987 • 7 citations

Ultrasound screening for structural defects in early pregnancy

1984 • 3 citations