Structures of regulatory regions in the human cytochrome P-450scc (desmolase) gene

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini

1983 • 532 citations

Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains.

1986 • 427 citations

Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.

1989 • 396 citations

5′–3′ Exonucleases in phosphorothioate-based oligonucleotide-directed mutagenesis

1988 • 336 citations

Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP.

1987 • 328 citations

Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements

1987 • 323 citations

Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element.

1987 • 293 citations

Clonal analysis of differentiated function in animal cell cultures. I. Possible correlated maintenance of differentiated function and the diploid karyotype.

1966 • 278 citations

Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.

1987 • 236 citations

Transcriptional regulation of steroid hydroxylase genes by corticotropin.

1986 • 219 citations

Gene Structure of Human Cytochrome P-450(SCC), Cholesterol Desmolase

1987 • 192 citations

Transcriptional regulation of the bovine CYP17 (P-450(17)alpha) gene. Identification of two cAMP regulatory regions lacking the consensus cAMP-responsive element (CRE).

1990 • 134 citations

Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450.

1984 • 121 citations

Characterization of the promoter/regulatory region of the bovine CYP11A (P-450scc) gene. Basal and cAMP-dependent expression.

1990 • 107 citations

Nucleotide sequence analysis of murine 21-hydroxylase genes: mutations affecting gene expression.

1986 • 102 citations

A cAMP-responsive Element Regulates Expression of the Mouse Steroid 11β-Hydroxylase Gene

1989 • 76 citations

pSV00CAT: low background CAT plasmid

1988 • 75 citations

Structural and Functional Analysis of the Promoter Region of the Gene Encoding Mouse Steroid 11β-Hydroxylase

1989 • 66 citations

An enhancer element and a functional cyclic AMP-dependent protein kinase are required for expression of adrenocortical 21-hydroxylase.

1988 • 64 citations

Regulation of cytochrome P-45011 beta gene expression by adrenocorticotropin.

1985 • 60 citations

The 5′‐flanking region of the human P‐450(SCC) gene shows responsiveness to CAMP‐dependent regulation in a transient gene‐expression system of Y‐1 adrenal tumor cells

1988 • 49 citations

Characterization of a regulatory region of the steroid 21-hydroxylase gene.

1986 • 47 citations

The 5′-region of the P450XIA1 (P450scc) gene contains a basal promoter and an adrenal-specific activating domain

1989 • 25 citations

Regulation of cholesterol side-chain cleavage cytochrome P-450 gene expression in adrenal cells in monolayer culture

1986 • 24 citations