The Olivocerebellar Projection Mediates Ibogaine-Induced Degeneration of Purkinje Cells: A Model of Indirect, Trans-Synaptic Excitotoxicity

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

The Cerebellum as a Neuronal Machine

1967 • 3,202 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Electrophysiological properties of in vitro Purkinje cell dendrites in mammalian cerebellar slices.

1980 • 1,759 citations

Cerebellar Cortex: Cytology and Organization

1974 • 1,705 citations

Cerebellar Cortex

1974 • 1,456 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

The excitatory synaptic action of climbing fibres on the Purkinje cells of the cerebellum

1966 • 956 citations

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

1993 • 905 citations

Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system

1971 • 808 citations

Differences in Ca2+ permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression

1994 • 661 citations

Oscillatory properties of guinea‐pig inferior olivary neurones and their pharmacological modulation: an in vitro study.

1986 • 653 citations

Electrotonic coupling between neurons in cat inferior olive.

1974 • 646 citations

Cellular localization of a metabotropic glutamate receptor in rat brain

1992 • 539 citations

The parasagittal zonation within the olivocerebellar projection. I. Climbing fiber distribution in the vermis of cat cerebellum

1977 • 531 citations

Structural study of inferior olivary nucleus of the cat: morphological correlates of electrotonic coupling.

1974 • 484 citations

Neurotoxicity of excitatory amino acids

1990 • 466 citations

The olivo-cerebellar system: Functional properties as revealed by harmaline-induced tremor

1973 • 457 citations

Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo

1988 • 437 citations

Inositol 1,4,5-trisphosphate receptor localized to endoplasmic reticulum in cerebellar Purkinje neurons

1989 • 431 citations

Synaptic currents in cerebellar Purkinje cells.

1990 • 407 citations

Inferior Olive: Its Role in Motor Learning

1975 • 388 citations

The Functional Organization of the Olivo‐Cerebellar System as Examined by Multiple Purkinje Cell Recordings

1989 • 370 citations

Electrophysiological properties of dendrites and somata in alligator Purkinje cells.

1971 • 351 citations

Histological evidence supporting the inferior olive as the major source of cerebellar climbing fibers in the rat

1974 • 349 citations

The inositol 1,4,5,-trisphosphate receptor in cerebellar Purkinje cells: quantitative immunogold labeling reveals concentration in an ER subcompartment.

1990 • 326 citations

Rhythmic activity induced by harmaline in the olivo-cerebello-bulbar system of the cat

1973 • 299 citations

�ber den Ursprung der Kletterfasern des Kleinhirns

1959 • 280 citations

Multiple Purkinje Cell Recording in Rodent Cerebellar Cortex

1989 • 279 citations

Excitatory synaptic currents in Purkinje cells

1990 • 267 citations

Synaptically activated increases in Ca2+ concentration in hippocampal CA1 pyramidal cells are primarily due to voltage-gated Ca2+ channels

1992 • 263 citations

Olivocerebellar projection: a review.

1980 • 253 citations

Effects of 3-acetylpyridine on the central nervous system of the rat, as demonstrated by silver methods

1974 • 240 citations

The olivocerebellar system. I. Delayed and slow inhibitory effects: An overlooked salient feature of cerebellar climbing fibers

1980 • 226 citations

Degeneration of purkinje cells in parasagittal zones of the cerebellar vermis after treatment with ibogaine or harmaline

1993 • 220 citations

Climbing fiber deafferentation: Its action on Purkinje cell dendritic spines

1975 • 210 citations

Effect of glutamate, aspartate and related derivatives on cerebellar Purkinje cell dendrites in the rat: an in vitro study

1982 • 198 citations

Ca2+ entry via AMPA/KA receptors and excitotoxicity in cultured cerebellar Purkinje cells.

1994 • 194 citations

Inferior olivary nuclear complex of the rat: Morphology and comments on the principles of organization within the olivocerebellar system

1987 • 192 citations

Harmaline-induced rhythmic activity of cerebellar and lower brain stem neurons

1971 • 191 citations

The cerebellar olivo-corticonuclear connections in the rat

1993 • 189 citations

The Central Role of Voltage-Activated and Receptor-Operated Calcium Channels in Neuronal Cells

1992 • 184 citations

100 years of ibogaine: neurochemical and pharmacological actions of a putative anti-addictive drug.

1995 • 178 citations

Ca2+ entry via AMPA/KA receptors and excitotoxicity in cultured cerebellar Purkinje cells

1994 • 163 citations

Intradendritic release of calcium induced by glutamate in cerebellar purkinje cells

1991 • 158 citations

A preliminary investigation of ibogaine: Case reports and recommendations for further study

1994 • 156 citations

Ionic requirements for neurotoxic effects of excitatory amino acid analogues in rat cerebellar slices

1986 • 153 citations

Inferior olive lesion induces long-lasting functional modification in the Purkinje cells

1984 • 143 citations

Aspartate-like and glutamate-like immunoreactivities in the inferior olive and climbing fibre system: A light microscopic and semiquantitative electron microscopic study in rat and baboon (Papio anubis)

1990 • 129 citations

Intracellularly recorded responses of the cerebellar Purkinje cells

1966 • 128 citations

Central neurotoxic effects of intraperitoneally administered 3-acetylpyridine, harmaline and niacinamide in Sprague-Dawley and Long-Evans rats: A critical review of central 3-acetylpyridine neurotoxicity

1985 • 126 citations

Expression of NMDA channels on cerebellar Purkinje cells acutely dissociated from newborn rats

1992 • 120 citations

Effects of ibogaine on acute signs of morphine withdrawal in rats: Independence from tremor

1992 • 119 citations

Reinnervation of cerebellar Purkinje cells by climbing fibres surviving a subtotal lesion of the inferior olive in the adult rat. I. Development of new collateral branches and terminal plexuses

1991 • 117 citations

Functional characterization of neuronal circuitry of frog cerebellar cortex.

1969 • 108 citations

Morphological Correlates of Bilateral Synchrony in the Rat Cerebellar Cortex

1996 • 106 citations

Cerebral Pharmacokinetics of Tremor-Producing Harmala and Iboga Alkaloids

1972 • 99 citations

Neurophysiological Studies of Harmaline-Induced Tremor in the Cat

1971 • 97 citations

EMG analysis of harmaline-induced tremor in normal and three strains of mutant mice with Purkinje cell degeneration and the role of the inferior olive

1995 • 75 citations

Harmaline-induced tremor in the rat: Abolition by 3-acetylpyridine destruction of cerebellar climbing fibers

1976 • 72 citations

Ibogaine induces glial activation in parasagittal zones of the cerebellum

1993 • 72 citations

NEUROPHARMACOLOGICAL STUDIES ON IBOGAINE, AN INDOLE ALKALOID WITH CENTRAL‐STIMULANT PROPERTIES

1957 • 68 citations

Harmaline-induced tremor

1981 • 67 citations

Excitotoxic insult due to ibogaine leads to delayed induction of neuronal NOS in Purkinje cells

1995 • 61 citations

Ibogaine neurotoxicity: a re-evaluation

1996 • 61 citations

Excitatory amino acids receptors of cerebellar purkinje cells: Development and plasticity

1991 • 60 citations

Mechanisms of calcium-related cell death.

1996 • 57 citations

Spatial Distribution of Climbing and Mossy Fibre Inputs into the Cerebellar Cortex

1976 • 56 citations

Quantitative effects of climbing fibre deafferentation on the adult Purkinje cell dendritic tree

1976 • 55 citations

[The olivocerebellar system].

1983 • 53 citations

A light and electron microscopic study of the effects of 3‐acetylpyridine intoxication on the inferior olivary complex and cerebellar cortex

1980 • 44 citations

Effects Produced by Local Applications of Harmaline in the Inferior Olive

1975 • 43 citations

Harmaline-induced rhythmic activity of alpha and gamma motoneurons in the cat

1973 • 41 citations

Pharmacokinetics in the rat of the hallucinogenic alkaloids harmine and harmaline

1974 • 33 citations

Structure-activity relationships of intracerebrally injected tremorigenic indole alkaloids

1973 • 30 citations

Activity in the olivo-cerebello-bulbar system of the cat during ibogaline- and oxotremorine-induced tremor

1974 • 30 citations

Sensitivity of rat inferior olivary neurons to 3-acetylpyridine

1984 • 23 citations

Effect of harmaline in monkeys with central nervous system lesions

1970 • 22 citations

Der Wirkungsmechanismus von wässrigem Torfextrakt auf die spontane kontraktile Aktivität der glatten Muskulatur

2000 • 21 citations

Calcium Permeability of Non‐N‐Methyl‐<scp>D</scp>‐Aspartate Receptor Channels in Immature Cerebellar Purkinje Cells: Studies Using Fura‐2 Microfluorometry

1993 • 18 citations

Calcium channels in cellular membranes

1990 • 10 citations