Double-Blind Randomized Phase II Study of the Combination of Sorafenib and Dacarbazine in Patients With Advanced Melanoma: A Report From the 11715 Study Group

BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

2004 • 3,873 citations

High-Dose Recombinant Interleukin 2 Therapy for Patients With Metastatic Melanoma: Analysis of 270 Patients Treated Between 1985 and 1993

1999 • 1,967 citations

Discovery and development of sorafenib: a multikinase inhibitor for treating cancer

2006 • 1,693 citations

Randomized Phase III Study of Temozolomide Versus Dacarbazine in the Treatment of Patients With Advanced Metastatic Malignant Melanoma

2000 • 1,252 citations

Phase III Multicenter Randomized Trial of the Dartmouth Regimen Versus Dacarbazine in Patients With Metastatic Melanoma

1999 • 756 citations

Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis

2006 • 636 citations

Bcl-2 Antisense (oblimersen sodium) Plus Dacarbazine in Patients With Advanced Melanoma: The Oblimersen Melanoma Study Group

2006 • 597 citations

High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update.

2000 • 500 citations

Malignant melanoma: prevention, early detection, and treatment in the 21st century

2000 • 448 citations

B-RAF is a therapeutic target in melanoma

2004 • 435 citations

Sequential Biochemotherapy Versus Chemotherapy for Metastatic Melanoma: Results From a Phase III Randomized Trial

2002 • 378 citations

Re-evaluating the role of dacarbazine in metastatic melanoma: what have we learned in 30 years?

2004 • 355 citations

Role of Raf Kinase in Cancer: Therapeutic Potential of Targeting the Raf/MEK/ERK Signal Transduction Pathway

2006 • 346 citations

Cutaneous melanoma

2005 • 281 citations

Efficacy and Safety of Tositumomab and Iodine-131 Tositumomab (Bexxar) in B-Cell Lymphoma, Progressive After Rituximab

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Interferon Alfa Therapy for Malignant Melanoma: A Systematic Review of Randomized Controlled Trials

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Results of interleukin-2-based treatment in advanced melanoma: a case record-based analysis of 631 patients.

1998 • 206 citations

Circulating 25-Hydroxyvitamin D Levels Predict Survival in Early-Stage Non–Small-Cell Lung Cancer Patients

2007 • 195 citations

Dacarbazine, Cisplatin, and Interferon-Alfa-2b With or Without Interleukin-2 in Metastatic Melanoma: A Randomized Phase III Trial (18951) of the European Organisation for Research and Treatment of Cancer Melanoma Group

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Systemic treatments for metastatic cutaneous melanoma

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A Population-Based Validation of the American Joint Committee on Cancer Melanoma Staging System

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The New Melanoma Staging System

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Brachytherapy: Current Status and Future Strategies — Can High Dose Rate Replace Low Dose Rate and External Beam Radiotherapy?

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Randomized phase III study of paclitaxel plus carboplatin with or without sorafenib as second-line treatment in patients with advanced melanoma

2007 • 70 citations

Preliminary results of a randomized phase II study comparing two schedules of temozolomide in combination with sorafenib in patients with advanced melanoma

2006 • 61 citations

Phase I trial of BAY 43–9006 (sorafenib) combined with dacarbazine (DTIC) in metastatic melanoma patients

2005 • 50 citations

Interleukin-2 for the treatment of melanoma.

2005 • 49 citations

Updated results of a randomized phase II study comparing two schedules of temozolomide in combination with sorafenib in patients with advanced melanoma

2007 • 37 citations

An open-label phase II study of sorafenib and dacarbazine as first-line therapy in patients with advanced melanoma

2007 • 26 citations

Phase II trial of sorafenib combined with dacarbazine in metastatic melanoma patients

2006 • 21 citations

Therapeutic targets in melanoma: MAPKinase pathway

2006 • 18 citations

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