Phase I Study of Doxil® and Vinorelbine in Patients with Advanced Malignancies

Reporting results of cancer treatment

1981 • 7,916 citations

Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes.

1994 • 1,355 citations

Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation.

1997 • 648 citations

Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi's sarcoma: results of a randomized phase III clinical trial.

1998 • 625 citations

Liposomal doxorubicin: antitumor activity and unique toxicities during two complementary phase I studies.

1995 • 476 citations

Randomized comparative trial of pegylated liposomal doxorubicin versus bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma. International Pegylated Liposomal Doxorubicin Study Group.

1998 • 354 citations

Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicenter phase II trial.

1997 • 299 citations

Hand-foot syndrome associated with liposome-encapsulated doxorubicin therapy

1995 • 173 citations

Efficacy of pegylated-liposomal doxorubicin in the treatment of AIDS-related Kaposi's sarcoma after failure of standard chemotherapy.

1997 • 170 citations

Liposomal-entrapped doxorubicin: an active agent in AIDS-related Kaposi's sarcoma.

1995 • 163 citations

Pharmacokinetics, Biodistribution and Therapeutic Efficacy of Doxorubicin Encapsulated in Stealth® Liposomes (Doxil®)

1994 • 148 citations

National Cancer Institute-Common Toxicity Criteria (NCI-CTC Version 2.0, Jan. 30, 1998)-日本語訳JCOG版-

1999 • 96 citations

Pharmacokinetics and metabolism of Navelbine.

1989 • 89 citations

Phase I pharmacologic study of a new Vinca alkaloid: Navelbine

1985 • 80 citations

A summary of vinorelbine (Navelbine) safety data from North American clinical trials.

1994 • 78 citations

Relationship of dose intensity to the induction of palmar-plantar erythrodysesthia by pegylated liposomal doxorubicin in dogs

1999 • 64 citations

Hand-foot syndrome following prolonged infusion of high doses of vinorelbine

1998 • 50 citations

Phase I study of Doxil and vinorelbine in metastatic breast cancer

1999 • 46 citations

Trimethoprim/sulfamethoxazole versus placebo: a double-blind comparison of infection prophylaxis in patients with small cell carcinoma of the lung.

1983 • 43 citations

A Phase I Study of a Daily ×3 Schedule of Intravenous Vinorelbine for Refractory Epithelial Ovarian Cancer

1998 • 37 citations

Relationship of dose intensity to the induction of palmar-plantar erythrodysesthia by pegylated liposomal doxorubicin in dogs

1999 • 30 citations

Combined doxorubicin/vinorelbine (Navelbine) therapy in the treatment of advanced breast cancer.

1995 • 23 citations

Epirubicin/vinorelbine as first line therapy in metastatic breast cancer

1998 • 20 citations

Phase I study of vinorelbine and ifosfamide in advanced non-small-cell lung cancer.

1997 • 19 citations

Respiratory Failure Following Vinorelbine Tartrate Infusion in a Patient With Non-small Cell Lung Cancer

1997 • 19 citations

Phase II dose-finding trial of CAELYX™ (Stealth® liposomal doxorubicin HCL) in the treatment of advanced breast cancer

1997 • 17 citations

Vinorelbine and epirubicin in metastatic breast cancer. A dose finding study

1995 • 17 citations

Phase I study of epirubicin plus vinorelbine with or without G-CSF in advanced non-small cell lung cancer

1993 • 16 citations

First-Line Vinorelbine-Mitoxantrone Combination in Metastatic Breast Cancer Patients Relapsing after an Adjuvant Anthracycline Regimen: Results of a Phase II Study

1998 • 13 citations

Treatment of Kaposi’s sarcoma with liposomal doxorubicin

1995 • 12 citations

A phase I study of sequential vinorelbine followed by paclitaxel

1999 • 11 citations

Phase I study of high-dose epirubicin and vinorelbine in previously untreated non-small-cell lung cancer stage IIIB-IV

1995 • 9 citations

A Dose Finding Study for the Combination of Epidoxorubicin and Vinorelbine, Delivered Every Two Weeks with G-CSF Support, in Advanced Breast Cancer

1998 • 7 citations

Daily times four vinorelbine plus cisplatin in advanced non-small-cell lung cancer: A phase II trial of a novel schedule

1999 • 5 citations

A phase I trial of vinorelbine in combination with mitoxantrone in patients with refractory solid tumors

1998 • 5 citations

Kinetic analysis in living cells of the inhibition of the P-glycoprotein-mediated efflux of anthracyclines by vinca alkaloids

1998 • 4 citations