The designer antiangiogenic peptide anginex targets tumor endothelial cells and inhibits tumor growth in animal models

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

1997 • 4,504 citations

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1995 • 4,003 citations

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1994 • 3,367 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Caspases: Intracellular Signaling by Proteolysis

1997 • 2,114 citations

Definition of Two Angiogenic Pathways by Distinct α _v Integrins

1995 • 1,333 citations

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

1990 • 1,062 citations

Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

2000 • 992 citations

Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation.

2000 • 827 citations

Angiostatin binds ATP synthase on the surface of human endothelial cells

1999 • 520 citations

Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32

1996 • 481 citations

The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation.

1995 • 456 citations

Quantitative angiogenesis assays: Progress and problems

1997 • 386 citations

Distinct Antitumor Properties of a Type IV Collagen Domain Derived from Basement Membrane

2000 • 347 citations

Vasostatin, a Calreticulin Fragment, Inhibits Angiogenesis and Suppresses Tumor Growth

1998 • 314 citations

Cell Surface Glypicans Are Low-Affinity Endostatin Receptors

2001 • 310 citations

Endothelial intercellular adhesion molecule-1 expression is suppressed in human malignancies: the role of angiogenic factors.

1996 • 268 citations

Synergy between angiostatin and endostatin: inhibition of ovarian cancer growth.

2000 • 228 citations

Mammary carcinoma model: correlation of macromolecular contrast-enhanced MR imaging characterizations of tumor microvasculature and histologic capillary density.

1996 • 210 citations

Inhibition of tumor growth and metastasis of rodent tumors by the angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (TNP-470; AGM-1470).

1993 • 164 citations

Angiogenesis inhibitor TNP-470 (AGM-1470) potently inhibits the tumor growth of hormone-independent human breast and prostate carcinoma cell lines.

1993 • 163 citations

Anginex, a designed peptide that inhibits angiogenesis

2001 • 161 citations

A potent inhibitor of endothelial cell proliferation is generated by proteolytic cleavage of the chemokine platelet factor 4.

1995 • 143 citations

Quantitative Assessment of Angiogenesis and Tumor Vessel Architecture by Computer-Assisted Digital Image Analysis: Effects of VEGF–Toxin Conjugate on Tumor Microvessel Density

2000 • 136 citations

CD44 Is Involved in Tumor Angiogenesis; an Activation Antigen on Human Endothelial Cells

1997 • 133 citations

Anginex, a designed peptide that inhibits angiogenesis

2001 • 111 citations

Bactericidal/permeability-increasing protein (BPI) inhibits angiogenesis via induction of apoptosis in vascular endothelial cells

2000 • 84 citations

A recipe for designing water‐soluble, β‐sheet‐forming peptides

1996 • 80 citations

Enhancement of CPP32-like Activity in the TNF-Treated U937 Cells by the Proteasome Inhibitors

1996 • 58 citations

Microvessel density in unknown primary tumors

1997 • 54 citations

Rocking the foundations of solid tumor growth by attacking the tumor's blood supply

1998 • 46 citations

Dissection of murine lymphocyte-endothelial cell interaction mechanisms by SV-40-transformed mouse endothelial cell lines: Novel mechanisms mediating basal binding, and α4-integrin-dependent cytokine-induced adhesion

1991 • 35 citations

Angiostatic Proteins and Peptides

2001 • 19 citations

The antiangiogenic properties of bactericidal/permeability-increasing protein (BPI)

2002 • 16 citations

Anti-angiogenic peptides

2017 • 1 citations