Induction of macrophage antitumor activity by acetylated low density lipoprotein containing lipophilic muramyl tripeptide.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

Efficient Trace-labelling of Proteins with Iodine

1958 • 2,571 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

The metabolism of very low density lipoprotein proteins I. Preliminary in vitro and in vivo observations

1972 • 1,831 citations

The Cell Biology of Macrophage Activation

1984 • 1,623 citations

Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein.

1984 • 1,249 citations

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

1976 • 1,032 citations

Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

1980 • 851 citations

Receptor-mediated endocytosis: insights from the lipoprotein receptor system.

1979 • 701 citations

Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity.

1984 • 471 citations

Acetoacetylated lipoproteins used to distinguish fibroblasts from macrophages in vitro by fluorescence microscopy.

1981 • 396 citations

Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide.

1981 • 322 citations

Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery.

1982 • 303 citations

Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells.

1985 • 219 citations

Mononuclear Phagocytes; Functional Aspects

1981 • 215 citations

Fate of the synthetic immunoadjuvant, muramyl dipeptide (14C-labelled) in the mouse

1979 • 200 citations

Mononuclear phagocytes : functional aspects

1980 • 172 citations

Effects of liposome structure and lipid composition on the activation of the tumoricidal properties of macrophages by liposomes containing muramyl dipeptide.

1982 • 168 citations

Macrophage stimulation by bacterial lipopolysaccharides. I. Cytolytic effect on tumor target cells.

1978 • 160 citations

Comparative effects of various classes of mouse interferons on macrophage activation for tumor cell killing.

1985 • 151 citations

Synergistic activation by recombinant mouse interferon-gamma and muramyl dipeptide of tumoricidal properties in mouse macrophages.

1985 • 124 citations

Receptors for Maleylated Proteins Regulate Secretion of Neutral Proteases by Murine Macrophages

1982 • 112 citations

Selective delivery of cytotoxic compounds to cells by the LDL pathway

1984 • 97 citations

Sequential activation of murine mononuclear phagocytes for tumor cytolysis: differential expression of markers by macrophages in the several stages of development.

1983 • 96 citations

Murine macrophage tumors are a source of a 260,000-dalton acetyl-low density lipoprotein receptor.

1985 • 93 citations

Activation of alveolar macrophage tumoricidal activity and eradication of experimental metastases by freeze-dried liposomes containing a new lipophilic muramyl dipeptide derivative.

1985 • 85 citations

Targeted killing of cultured cells by receptor-dependent photosensitization.

1981 • 77 citations

Protection of Mice Against Fatal Herpes Simplex Type 2 Infection by Liposomes Containing Muramyl Tripeptide

1985 • 67 citations

In-vivo activity of antivirals against exotic RNA viral infections

1984 • 63 citations

Enhancement of non-specific resistance to viral infection by muramyldipeptide and its analogs

1985 • 58 citations

Preparation and interaction of a low-density lipoprotein:daunomycin complex with P388 leukemic cells.

1984 • 55 citations

Delivery of Lipophilic Drugs Using Lipoproteinsa

1987 • 50 citations

Observations on the Passage of Apoproteins from Plasma Lipoproteins into Peripheral Lymph in Two Men

1975 • 43 citations

Selective uptake of a toxic lipophilic anthracycline derivative by the low density lipoprotein receptor pathway in cultured fibroblasts

1985 • 42 citations

Stimulation of chemiluminescence and resistance against aerogenic influenza virus infection by synthetic muramyl dipeptide combined with trehalose dimycolate

1984 • 34 citations

Effect of muramyl dipeptide and its stearoyl derivatives on resistance to Sendai virus infection in mice

1985 • 32 citations

Enhancement of host resistance against virus infections by MTP-PE, a synthetic lipophilic muramyl peptide — I. Increased survival in mice and guinea pigs after single drug administration prior to infection, and the effect of MTP-PE on interferon levels in sera and lungs

1986 • 30 citations

Heterogeneity of macrophages in response to lymphokines and other signals

1982 • 21 citations

Biologicals and Biological Response Modifiers: New Approaches to Cancer Treatment

1985 • 20 citations

Comparison of Five Short-Term Assays That Measure Nonspecific Cytotoxicity Mediated to Tumor Cells by Activated Macrophages

1986 • 19 citations

Functional and biochemical heterogeneity among subpopulations of rat and mouse peritoneal macrophages.

1982 • 16 citations

Characteristics of uptake and cytotoxicity of a low-density lipoprotein-daunomycin complex in P388 leukemic cells.

1984 • 10 citations