Evidence for a two-step mechanism involved in assembly of functional signal recognition particle receptor.

Mechanisms for the incorporation of proteins in membranes and organelles.

1982 • 875 citations

Protein translocation across the endoplasmic reticulum

1984 • 825 citations

[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 • 679 citations

Secretory protein translocation across membranes—the role of the ‘docking protein’

1982 • 648 citations

Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor.

1982 • 478 citations

Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle.

1982 • 388 citations

Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change.

1985 • 341 citations

Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle.

1986 • 337 citations

The signal sequence of nascent preprolactin interacts with the 54K polypeptide of the signal recognition particle

1986 • 336 citations

[30] The isolation of outer and inner mitochondrial membranes

1974 • 300 citations

Translocation of secretory proteins across the microsomal membrane occurs through an environment accessible to aqueous perturbants

1985 • 277 citations

Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: Analysis of biochemical mutants of SRP

1988 • 248 citations

The signal recognition particle receptor is a complex that contains two distinct polypeptide chains.

1986 • 189 citations

Transient involvement of signal recognition particle and its receptor in the microsomal membrane prior to protein translocation

1983 • 160 citations

Mechanisms of integration of de novo-synthesized polypeptides into membranes: signal-recognition particle is required for integration into microsomal membranes of calcium ATPase and of lens MP26 but not of cytochrome b5.

1983 • 155 citations

A membrane component essential for vectorial translocation of nascent proteins across the endoplasmic reticulum: requirements for its extraction and reassociation with the membrane.

1980 • 140 citations

Topology of signal recognition particle receptor in endoplasmic reticulum membrane

1985 • 140 citations

Characterization of secretory protein translocation: ribosome-membrane interaction in endoplasmic reticulum.

1986 • 121 citations

Import of honeybee prepromelittin into the endoplasmic reticulum: structural basis for independence of SRP and docking protein.

1987 • 113 citations

A former amino terminal signal sequence engineered to an internal location directs translocation of both flanking protein domains.

1985 • 98 citations

Import of honeybee prepromelittin into the endoplasmic reticulum. Requirements for membrane insertion, processing, and sequestration.

1986 • 71 citations

A structural and functional analysis of the docking protein. Characterization of active domains by proteolysis and specific antibodies.

1985 • 61 citations

A stop transfer sequence recognizes receptors for nascent chain translocation across the endoplasmic reticulum membrane

1986 • 54 citations

Sequences beyond the cleavage site influence signal peptide function.

1988 • 48 citations

Different Modes of Membrane Interactions of the Signal Sequence of Carp Preproinsulin and of the Insertion Sequence of Rabbit Cytochrome b₅

1982 • 41 citations

Complete cDNA sequence coding for human docking protein

1988 • 30 citations

The human docking protein does not associate with the membrane of the rough endoplasmic reticulum via a signal or insertion sequence-mediated mechanism

1988 • 17 citations

Transport of Proteins into and across the Endoplasmic Reticulum Membrane

1988 • 4 citations