The structure of human liver fructose-1,6-bisphosphate aldolase

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

Improved Fourier coefficients for maps using phases from partial structures with errors

1986 • 1,897 citations

The Catalytic Activity of Carboxypeptidase-degraded Aldolase

1959 • 185 citations

Molecular analysis of aldolase B genes in hereditary fructose intolerance

1990 • 118 citations

Activity and specificity of human aldolases

1991 • 104 citations

Catalytic deficiency of human aldolase B in hereditary fructose intolerance caused by a common missense mutation

1988 • 98 citations

The crystal structure of fructose‐1,6‐bisphosphate aldolase fromDrosophila melanogaster at 2.5A˚resolution

1991 • 75 citations

Crystal Structure of Fructose-1,6-bisphosphate Aldolase from the Human Malaria Parasite Plasmodium falciparum^,

1998 • 72 citations

The crystal structure of human muscle aldolase at 3.0 Å resolution

1990 • 61 citations

The complete amino acid sequence of the human aldolase C isozyme derived from genomic clones

1987 • 60 citations

Hereditary fructose intolerance: A difficult diagnosis in the adult

1978 • 59 citations

Structure of a Fructose-1,6-bis(phosphate) Aldolase Liganded to Its Natural Substrate in a Cleavage-Defective Mutant at 2.3 Å^,

1999 • 58 citations

Affinity labeling of a previously undetected essential lysyl residue in class I fructose bisphosphate aldolase.

1976 • 56 citations

Expression, Purification, and Characterization of Natural Mutants of Human Aldolase B

2000 • 45 citations

Differential usage of the carboxyl-terminal region among aldolase isozymes

1993 • 39 citations

Carboxyl terminus region modulates catalytic activity of recombinant maize aldolase.

1991 • 30 citations

Construction and properties of active chimeric enzymes between human aldolases A and B. Analysis of molecular regions which determine isozyme-specific functions.

1990 • 25 citations

Association of the widespread A149P hereditary fructose intolerance mutation with newly identified sequence polymorphisms in the aldolase B gene.

1993 • 22 citations

Molecular Analysis of Aldolase B Genes in the Diagnosis of Hereditary Fructose Intolerance in the United Kingdom

1989 • 20 citations

Alteration of substrate specificity by a naturally-occurring aldolase B mutation (Ala337→Val) in fructose intolerance

1999 • 16 citations

Isozyme-specific modules on human aldolase A molecule. Isozyme group-specific sequences 1 and 4 are required for showing characteristics as aldolase A.

1993 • 15 citations

Characterization of Recombinant Human Aldolase B and Purification by Metal Chelate Chromatography

1995 • 13 citations

Fructose-1, 6-bisphosphate aldolase from rabbit muscle: Different catalytic behavior of the dihydroxyacetone phosphate binding sites at low temperature

1984 • 8 citations

Spectroscopic evidence for NADH-induced conformational changes in rabbit muscle aldolase

1991 • 7 citations

Topography and conformational changes of fructose-1,6-bisphosphate aldolase.

1991 • 4 citations