PARATHYROID HORMONE‐RELATED PROTEIN IN HYPERCALCAEMIA OF MALIGNANCY

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Case 39-2000

2000 • 3,891 citations

A Parathyroid Hormone-Related Protein Implicated in Malignant Hypercalcemia: Cloning and Expression

1987 • 1,293 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

Parathyroid hormone-related protein purified from a human lung cancer cell line.

1987 • 735 citations

Biochemical Evaluation of Patients with Cancer-Associated Hypercalcemia

1980 • 715 citations

Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy.

1988 • 431 citations

A single mouse α-amylase gene specifies two different tissue-specific mRNAs

1981 • 402 citations

Expression of a Calcium-Mobilizing Parathyroid Hormone-Like Peptide in Lactating Mammary Tissue

1988 • 387 citations

Parathyroid Hormone-Related Protein of Malignancy: Active Synthetic Fragments

1987 • 374 citations

Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy.

1987 • 373 citations

Prediction of sequential antigenic regions in proteins

1985 • 361 citations

Similarity of Synthetic Peptide from Human Tumor to Parathyroid Hormone in Vivo and in Vitro

1987 • 357 citations

Bovine Parathyroid Hormone: Minimum Chain Length of Synthetic Peptide Required for Biological Activity

1973 • 341 citations

Parathyroid Hormone in Plasma in Adenomatous Hyperparathyroidism, Uremia, and Bronchogenic Carcinoma

1966 • 339 citations

The hypercalcemia of malignancy: Pathogenesis and management

1982 • 317 citations

Nonparathyroid Humoral Hypercalcemia in Patients with Neoplastic Diseases

1973 • 285 citations

Evidence for a novel parathyroid hormone-related protein in fetal lamb parathyroid glands and sheep placenta: comparisons with a similar protein implicated in humoral hypercalcaemia of malignancy

1988 • 283 citations

Effects of a synthetic peptide of a parathyroid hormone-related protein on calcium homeostasis, renal tubular calcium reabsorption, and bone metabolism in vivo and in vitro in rodents.

1988 • 271 citations

Production of Parathyroid Hormone by Nonparathyroid Tumors¹

1967 • 234 citations

Factors associated with humoral hypercalcemia of malignancy stimulate adenylate cyclase in osteoblastic cells.

1983 • 225 citations

Parathyroid hormone-related protein: Immunohistochemical localization in cancers and in normal skin

1989 • 225 citations

A Parathyroid Hormone-Like Protein from Cultured Human Keratinocytes

1986 • 216 citations

Nucleotide sequence of the human parathyroid hormone gene.

1983 • 206 citations

Human renal carcinoma expresses two messages encoding a parathyroid hormone-like peptide: evidence for the alternative splicing of a single-copy gene.

1988 • 195 citations

Identification of adenylate cyclase-stimulating activity and cytochemical glucose-6-phosphate dehydrogenase-stimulating activity in extracts of tumors from patients with humoral hypercalcemia of malignancy.

1983 • 180 citations

A CCAAT DNA binding factor consisting of two different components that are both required for DNA binding.

1988 • 175 citations

Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors.

1983 • 174 citations

Highly conserved sequencim in the 3′ untranslated region of mRNAs coding for homologous proteins in distantly related species

1985 • 155 citations

Gene expression and cAMP.

1985 • 153 citations

Tumor products and the hypercalcemia of malignancy.

1985 • 151 citations

Nucleotide sequence surrounding multiple polyadenylation sites in the mouse dihydrofolate reductase gene.

1982 • 146 citations

Antibodies to parathyroid hormone-related protein lower serum calcium in athymic mouse models of malignancy-associated hypercalcemia due to human tumors.

1988 • 146 citations

Immunoreactive Forms of Circulating Parathyroid Hormone in Primary and Ectopic Hyperparathyroidism

1974 • 135 citations

REVIEW THE BIOSYNTHESIS OF HORMONES BY NON-ENDOCRINE TUMOURS-A REVIEW

1975 • 133 citations

Identification of transcripts encoding a parathyroid hormone-like peptide in messenger RNAs from a variety of human and animal tumors associated with humoral hypercalcemia of malignancy.

1988 • 132 citations

Hypercalcemia and Increased Parathyroid-Hormone Activity in a Primary Hepatoma

1970 • 125 citations

Case 27461

1941 • 124 citations

Some thoughts on the nature of ectopic parathyroid hormones

1971 • 124 citations

Malignancy-Associated Hypercalcemia: Evaluation with a Cytochemical Bioassay for Parathyroid Hormone*

1981 • 121 citations

Structure of the 5' flanking region of the gene encoding human parathyroid-hormone-related protein (PTHrP)

1989 • 110 citations

Immunoreactive calcitonin production by human lung carcinoma cells in culture

1975 • 98 citations

Expression of parathyroid hormone related protein in normal skin and in tumours of skin and skin appendages

1989 • 96 citations

ELEVATED NEPHROGENOUS CYCLIC AMP WITH NORMAL SERUM PARATHYROID HORMONE LEVELS IN PATIENTS WITH LUNG CANCER

1980 • 93 citations

Clinical Evaluation of Calcium Metabolism in Adult T-Cell Leukemia/Lymphoma

1988 • 90 citations

Urinary and Nephrogenous Adenosine 3′,5′-Monophosphate in the Hypercalcemia of Malignancy*

1981 • 90 citations

Ectopic secretion of parathyroid hormone by a renal adenocarcinoma in a patient with hypercalcaemia.

1970 • 89 citations

Relative contribution of humoral and metastatic factors to the pathogenesis of hypercalcaemia in malignancy.

1984 • 83 citations

Characterization of the mouse SPARC/osteonectin gene. Intron/exon organization and an unusual promoter region.

1988 • 82 citations

Two Distinct Tumor-Derived, Parathyroid Hormone-Like Peptides Result from Alternative Ribonucleic Acid Splicing

1988 • 81 citations

Alteration of Bile Canalicular Enzymes in Cholestasis. A POSSIBLE CAUSE OF BILE SECRETORY FAILURE

1973 • 77 citations

Cytochemical bioassay of parathyroid hormone in maternal and cord blood.

1985 • 76 citations

Expression of parathyroid hormone-related protein in a human T cell lymphotrophic virus type I-infected T cell line

1988 • 71 citations

Measurement of parathyroid hormone-related protein in extracts of fetal parathyroid glands and placental membranes

1990 • 66 citations

Bone resorption by isolated chick osteoclasts in culture is stimulated by murine spleen cell supernatant fluids (Osteoclast-Activating Factor) and inhibited by calcitonin and prostaglandin E2

1988 • 64 citations

Parathyroid hormone production and malignancy.

1972 • 63 citations

The unique endocrine milieu of the fetus.

1986 • 63 citations

Hypercalcemia associated with immunoreactive parathyroid hormone in a malignant rhabdoid tumor of the kidney (Rhabdoid Wilms' tumor)

1984 • 61 citations

The effect of fetal thyroparathyroidectomy on the transport of calcium across the ovine placenta to the fetus

1986 • 54 citations

Secretion of prostaglandins as bone-resorbing agents by renal cortical carcinoma in culture

1977 • 52 citations

Clinical Endocrinology of Calcium Metabolism

1988 • 49 citations

Regional localization of DNA probes on the short arm of chromosome 11 using aniridia-Wilms' tumor-associated deletions

1987 • 43 citations

Synthesis and Release of Parathyroid Hormone by a Renal Carcinoma in Cell Culture

1973 • 43 citations

Immunochemical Localization of Parathyroid Hormone in Cancer Tissue from Patients with Ectopic Hyperparathyroidism

1974 • 39 citations

Rat Parathyroid Hormone-(1–34) Fragment: Renal Adenylate Cyclase Activity and Receptor Binding Propertiesin Vitro*

1985 • 39 citations

Hormonal influences on bone cells

1987 • 35 citations

Actions of parathyroid hormone-related protein on the rat kidney in vivo

1989 • 32 citations

FURTHER EVIDENCE FOR A PARATHYROID HORMONE‐RELATED PROTEIN IN FETAL PARATHYROID GLANDS OF SHEEP

1988 • 29 citations

A model for malignancy-associated humoral hypercalcemia

1984 • 25 citations

Messenger Ribonucleic Acid from Tumors Associated with Humoral Hypercalcemia of Malignancy Directs the Synthesis of a Secretory Parathyroid Hormone-Like Peptide*

1985 • 24 citations

Actions of synthetic parathyroid hormone-related protein(1–34) on the isolated rat kidney

1989 • 24 citations

Bone and kidney adenylate cyclase-stimulating activity produced by a hypercalcemic canine adenocarcinoma line (CAC-8) maintained in nude mice.

1987 • 21 citations

Localization of parathyroid hormone-like substance in squamous cell carcinomas. An immunoperoxidase study with ultrastructural correlation.

1985 • 20 citations

Efficacy and specificity of human parathyroid hormone analogues as antagonists in intact clonal osteogenic sarcoma cells

1986 • 17 citations

HUMORAL HYPERCALCEMIA OF MALIGNANCY: INVOLVEMENT OF A NOVEL HORMONE

1988 • 12 citations

Biologically Active Parathyroid Hormone in Foetal and Maternal Plasma

1981 • 12 citations

The Multi-Wire Proportional Counter for the Detection of 3H in Biological Systems

1981 • 1 citations