Regulation of albumin gene expression in a series of rat hepatocyte cell lines immortalized by simian virus 40 and maintained in chemically defined medium.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies

1966 • 4,504 citations

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

1969 • 4,428 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

Assay of tyrosine transaminase activity by conversion of p-hydroxyphenylpyruvate to p-hydroxybenzaldehyde

1966 • 762 citations

Adaptation of the rat liver tyrosine-α-ketoglutarate transaminase

1957 • 419 citations

Onco-developmental gene expression

1976 • 401 citations

Characterization of differentiated and dedifferentiated clones from a rat hepatoma

1975 • 381 citations

Hepatocyte proliferation in vitro: its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix.

1984 • 376 citations

A genetic analysis of extinction: Trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells

1984 • 365 citations

Maintenance of differentiated rat hepatocytes in primary culture.

1985 • 358 citations

CYTOMORPHOMETRY OF DEVELOPING RAT LIVER AND ITS APPLICATION TO ENZYMIC DIFFERENTIATION

1972 • 317 citations

Changes in Liver-Specific Compared to Common Gene Transcription During Primary Culture of Mouse Hepatocytes

1983 • 316 citations

HEPATOMAS IN TISSUE CULTURE COMPARED WITH ADAPTING LIVER IN VIVO.

1964 • 314 citations

Dependence of liver-specific transcription on tissue organization.

1985 • 230 citations

Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes.

1983 • 206 citations

Long-Term Co-Cultures of Adult Human Hepatocytes with Rat Liver Epithelial Cells: Modulation of Albumin Secretion and Accumulation of Extracellular Material

1984 • 183 citations

Posttranscriptional modulation of gene expression in cultured rat hepatocytes.

1984 • 161 citations

Synthesis and secretion of rat albumin in vivo, in perfused liver, and in isolated hepatocytes. Effects of hypophysectomy and growth hormone treatment.

1977 • 136 citations

Glucocorticoid-dependent expression of the albumin gene in adult rat hepatocytes.

1986 • 118 citations

Maintenance of adult rat liver slices in dynamic organ culture

1986 • 105 citations

Tissue-specific expression of the rat albumin gene: genetic control of its extinction in microcell hybrids.

1986 • 100 citations

A Mouse Hepatoma Cell Line which Secretes Several Serum Proteins Including Albumin and α-foetoprotein

1975 • 92 citations

Liver-Specific RNA Metabolism in Hepatoma Cells: Variations in Transcription Rates and mRNA Levels

1985 • 91 citations

Transformation of rat hepatocytes by transfection with simian virus 40 DNA to yield proliferating differentiated cells.

1986 • 89 citations

Quantitative assay for albumin-producing liver cells after simian virus 40 transformation of rat hepatocytes maintained in chemically defined medium.

1984 • 83 citations

Reciprocal modulation of growth and liver functions of mature rat hepatocytes in primary culture by an extract of hepatic plasma membranes.

1984 • 75 citations

Dependence of Liver-Specific Transcription on Tissue Organization

1985 • 72 citations

Coordinated modulation of albumin synthesis and mRNA levels in cultured hepatoma cells by hydrocortisone and cyclic AMP analogs.

1979 • 69 citations

Expression of the albumin gene in rat hepatoma cells and their dedifferentiated variants

1981 • 66 citations

Liver-specific RNA metabolism in hepatoma cells: variations in transcription rates and mRNA levels.

1985 • 60 citations

Temperature-sensitive adult liver cell line dependent on glucocorticoid for differentiation.

1983 • 56 citations

Hormonal control of alpha-fetoprotein secretion in human hepatoma cell lines proliferating in chemically defined medium.

1985 • 51 citations

Posttranscriptional Modulation of Gene Expression in Cultured Rat Hepatocytes

1984 • 44 citations

Loss of reciprocal modulations of growth and liver function of hepatoma cells in culture by contact with cells or cell membranes.

1984 • 35 citations

DNA synthesis in isolated hepatocytes infected with herpesviruses

1980 • 30 citations

Serum-free growth of HTC cells containing glucocorticoid- and insulin-inducible tyrosine aminotransferase and cytoplasmic glucocorticoid receptors

1975 • 30 citations

The influence of glucocorticoid on albumin synthesis and its messenger RNA in rat in vivo and in hepatocyte suspension culture

1985 • 28 citations

Effect of simian virus 40 infection on albumin production by hepatocytes cultured in chemically defined medium and plated on collagen and non-collagen attachment surfaces.

1984 • 23 citations

Rates of Albumin and Transferrin Synthesis <italic>In Vitro</italic> in Rat Hepatoma-Derived H<sub>4</sub> II-EC<sub>3</sub> Cells<xref ref-type="fn" rid="FN2">2</xref>

1969 • 23 citations

The effect of dexamethasone on albumin production by fetal rat hepatocytes in culture.

1985 • 23 citations

Plasma-protein production by rat hepatoma cells in culture, their variants and revertants

1986 • 19 citations

Temperature-Sensitive Adult Liver Cell Line Dependent on Glucocorticoid for Differentiation

1983 • 13 citations

Cloning of rat .alpha.-fetoprotein 3'-terminal complementary deoxyribonucleic acid sequences and preparation of radioactively labeled hybridization probes from cloned deoxyribonucleic acid inserts

1981 • 12 citations