Small Cell Lung Cancer*

PERIODATE-LYSINE-PARAFORMALDEHYDE FIXATIVE A NEW FIXATIVE FOR IMMUNOELECTRON MICROSCOPY

1974 • 3,882 citations

Prophylactic Cranial Irradiation for Patients with Small-Cell Lung Cancer in Complete Remission

1999 • 1,607 citations

Twice-Daily Compared with Once-Daily Thoracic Radiotherapy in Limited Small-Cell Lung Cancer Treated Concurrently with Cisplatin and Etoposide

1999 • 1,394 citations

Irinotecan plus Cisplatin Compared with Etoposide plus Cisplatin for Extensive Small-Cell Lung Cancer

2002 • 1,346 citations

A Meta-Analysis of Thoracic Radiotherapy for Small-Cell Lung Cancer

1992 • 1,295 citations

Topotecan Versus Cyclophosphamide, Doxorubicin, and Vincristine for the Treatment of Recurrent Small-Cell Lung Cancer

1999 • 909 citations

Does thoracic irradiation improve survival and local control in limited-stage small-cell carcinoma of the lung? A meta-analysis.

1992 • 802 citations

Importance of timing for thoracic irradiation in the combined modality treatment of limited-stage small-cell lung cancer. The National Cancer Institute of Canada Clinical Trials Group.

1993 • 716 citations

MEDICAL RESEARCH COUNCIL COMPARATIVE TRIAL OF SURGERY AND RADIOTHERAPY FOR PRIMARY TREATMENT OF SMALL-CELLED OR OAT-CELLED CARCINOMA OF BRONCHUS

1973 • 528 citations

Keynote address on biostatistics and data retrieval.

1973 • 476 citations

Prophylactic cranial irradiation is indicated following complete response to induction therapy in small cell lung cancer: Results of a multicentre randomised trial

1997 • 363 citations

Alkylating agents in bronchogenic carcinoma

1969 • 353 citations

Twenty Years of Phase III Trials for Patients With Extensive-Stage Small-Cell Lung Cancer: Perceptible Progress

1999 • 351 citations

Initial versus delayed accelerated hyperfractionated radiation therapy and concurrent chemotherapy in limited small-cell lung cancer: a randomized study.

1997 • 339 citations

Antibodies to intermediate filament proteins in the immunohistochemical identification of human tumours: an overview

1983 • 324 citations

A Prospective Randomized Trial to Determine the Benefit of Surgical Resection of Residual Disease Following Response of Small Cell Lung Cancer to Combination Chemotherapy

1994 • 309 citations

Topotecan Versus Observation After Cisplatin Plus Etoposide in Extensive-Stage Small-Cell Lung Cancer: E7593—A Phase III Trial of the Eastern Cooperative Oncology Group

2001 • 289 citations

Is there a case for cisplatin in the treatment of small-cell lung cancer? A meta-analysis of randomized trials of a cisplatin-containing regimen versus a regimen without this alkylating agent

2000 • 282 citations

Prospective evaluation of the clinical value of planar bone scans, SPECT, and (18)F-labeled NaF PET in newly diagnosed lung cancer.

2001 • 261 citations

Surgical resection in the management of small cell carcinoma of the lung

1982 • 255 citations

Initial Chemotherapeutic Doses and Survival in Patients with Limited Small-Cell Lung Cancer

1993 • 249 citations

Angiography in Pulmonary Embolism

1963 • 231 citations

Superiority of Alternating Non-Cross-Resistant Chemotherapy in Extensive Small Cell Lung Cancer

1987 • 227 citations

Comparison of oral etoposide and standard intravenous multidrug chemotherapy for small-cell lung cancer: a stopped multicentre randomised trial

1996 • 226 citations

Improving Survival Without Reducing Quality of Life in Small-Cell Lung Cancer Patients by Increasing the Dose-Intensity of Chemotherapy With Granulocyte Colony-Stimulating Factor Support: Results of a British Medical Research Council Multicenter Randomized Trial

2000 • 224 citations

Multimodal therapy for limited small-cell lung cancer: a randomized study of induction combination chemotherapy with or without thoracic radiation in complete responders; and with wide-field versus reduced-field radiation in partial responders: a Southwest Oncology Group Study.

1987 • 212 citations

Five-Day Oral Etoposide2 Treatment for Advanced Small-Cell Lung Cancer: Randomized Comparison With Intravenous Chemotherapy

1997 • 208 citations

Phase III Comparison of Twice-Daily Split-Course Irradiation Versus Once-Daily Irradiation for Patients With Limited Stage Small-Cell Lung Carcinoma

1999 • 203 citations

Phase I study to determine the maximum-tolerated dose of radiation in standard daily and hyperfractionated-accelerated twice-daily radiation schedules with concurrent chemotherapy for limited-stage small-cell lung cancer.

1998 • 195 citations

Etoposide (VP-16) and cisplatin: an effective treatment for relapse in small-cell lung cancer.

1985 • 188 citations

Randomized study of initial versus late chest irradiation combined with chemotherapy in limited-stage small-cell lung cancer. Aarhus Lung Cancer Group.

1997 • 174 citations

Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer. West Japan Lung Cancer Group.

1998 • 170 citations

Survival with inoperable lung cancer.An integration of prognostic variables based on simple clinical criteria

1977 • 169 citations

Solitary Pulmonary Nodule

2011 • 160 citations

A multicenter randomized clinical trial comparing paclitaxel–cisplatin–etoposide versus cisplatin–etoposide as first-line treatment in patients with small-cell lung cancer

2001 • 159 citations

Cisplatin plus etoposide with and without ifosfamide in extensive small-cell lung cancer: a Hoosier Oncology Group study.

1995 • 157 citations

Clinical biology of small cell carcinoma: relationship to surgical therapy.

1978 • 152 citations

Effects of granulocyte-macrophage colony-stimulating factor and dose intensification of V-ICE chemotherapy in small-cell lung cancer: a prospective randomized study of 300 patients.

1998 • 147 citations

A preliminary report: Concurrent twice-daily radiotherapy plus platinum-etoposide chemotherapy for limited small cell lung cancer

1988 • 142 citations

Randomized trial of alternating versus sequential radiotherapy/chemotherapy in limited-disease patients with small-cell lung cancer: a European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group Study.

1997 • 139 citations

Similar outcome of elderly patients in Intergroup Trial 0096

2000 • 130 citations

FDG-PET imaging for the staging and follow-up of small cell lung cancer

2001 • 129 citations

Cisplatin plus etoposide consolidation following cyclophosphamide, doxorubicin, and vincristine in limited small-cell lung cancer.

1988 • 125 citations

Lung cancer: Clinical trial of radiotherapy alone vs. Radiotherapy plus cyclophosphamide

1972 • 123 citations

Surgical treatment for limited small-cell lung cancer

1991 • 123 citations

Thoracic radiation therapy added to chemotherapy for small-cell lung cancer: an update of Cancer and Leukemia Group B Study 8083.

1998 • 119 citations

Small cell lung cancer

1979 • 119 citations

Combined modality induction therapy without maintenance chemotherapy for small cell carcinoma of the lung.

1984 • 114 citations

Long-term results in combined-modality treatment of small cell carcinoma of the lung.

1978 • 112 citations

Intensive weekly chemotherapy for the treatment of extensive-stage small-cell lung cancer.

1991 • 112 citations

Prophylactic irradiation in bronchogenic small cell anaplastic carcinoma. A comparative trial of localized versus extensive radiotherapy including prophylactic brain irradiation in patients receiving combination chemotherapy

1980 • 109 citations

Limited-stage small-cell lung cancer: patterns of intrathoracic recurrence and the implications for thoracic radiotherapy.

1994 • 109 citations

Staging procedures and prognostic features in small cell anaplastic bronchogenic carcinoma.

1978 • 105 citations

Combination of irinotecan and etoposide for treatment of refractory or relapsed small-cell lung cancer.

1998 • 101 citations

The influence of age on the delivery, tolerance, and efficacy of thoracic irradiation in the combined modality treatment of limited stage small cell lung cancer

1999 • 97 citations

Small cell lung cancer: progress and perspectives.

1978 • 96 citations

Importance of radiation dose in achieving improved loco-regional tumor control in limited stage small-cell lung carcinoma: An update

1989 • 96 citations

Neurological and cognitive impairment in long-term survivors of small cell lung cancer

1994 • 95 citations

Maintenance chemotherapy for small cell lung cancer: a critical review of the literature

1998 • 94 citations

Abbreviated treatment for elderly, infirm, or noncompliant patients with limited-stage small-cell lung cancer.

1998 • 91 citations

Dose-intensity of a four-drug chemotherapy regimen with or without recombinant human granulocyte-macrophage colony-stimulating factor in extensive-stage small-cell lung cancer: a multicenter randomized phase III study.

1997 • 85 citations

Multiple-drug weekly chemotherapy versus standard combination regimen in small-cell lung cancer: a phase III randomized study conducted by the European Lung Cancer Working Party.

1993 • 80 citations

Phase III study of intensive weekly chemotherapy with recombinant human granulocyte colony-stimulating factor versus standard chemotherapy in extensive-disease small-cell lung cancer. The Japan Clinical Oncology Group.

1998 • 80 citations

Combination Chemotherapy and Radiation Therapy for Small Cell Carcinoma

1977 • 78 citations

The importance of surgical and multimodality treatment for small cell bronchial carcinoma

1989 • 77 citations

Controlled study of survival of patients with clinically inoperable lung cancer treated with radiation therapy

1966 • 73 citations

Randomized trial comparing weekly versus 3-week chemotherapy in small-cell lung cancer: a Cancer Research Campaign trial.

1994 • 71 citations

Sequelae in long-term survivors of small cell lung cancer

1996 • 70 citations

Sequencing and schedule effects of cisplatin plus etoposide in small-cell lung cancer: results of a North Central Cancer Treatment Group randomized clinical trial.

1994 • 69 citations

Positron Emission Tomography in the Staging of Small-Cell Lung Cancer

2001 • 69 citations

VP-16 alone and in combination with cisplatin in previously treated patients with small cell lung cancer

1984 • 68 citations

New combination of the old drugs for elderly patients with small-cell lung cancer: a phase II study of the PAVE regimen.

1998 • 64 citations

Surgery in the management of small cell lung cancer

1997 • 63 citations

Comparison of split-course radiation therapy and continuous radiation therapy for unresectable bronchogenic carcinoma: 5 year results

1976 • 61 citations

Phase II trial of carboplatin plus oral etoposide for elderly patients with small-cell lung cancer

1998 • 55 citations

Cisplatin, Etoposide, and Paclitaxel in the Treatment of Patients With Extensive Small-Cell Lung Carcinoma

1999 • 54 citations

CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer

1997 • 53 citations

Randomized phase II study of cyclophosphamide, doxorubicin, and vincristine compared with single-agent carboplatin in patients with poor prognosis small cell lung carcinoma

2001 • 52 citations

Effect of initial resection of small-cell carcinoma of the lung: a review of Southwest Oncology Group Study 7628.

1985 • 51 citations

Practice guideline on prophylactic cranial irradiation in small-cell lung cancer

2001 • 50 citations

RESULTS OF RESECTION FOR OAT-CELL CARCINOMA OF THE LUNG

1968 • 49 citations

Influence of surgical resection prior to chemotherapy on the long-term results in small cell lung cancer. A study of 150 operable patients

1986 • 46 citations

Results of preoperative mediastinoscopy for small cell lung cancer

2000 • 41 citations

Immunoperoxidase staining on frozen tissue sections as a first screening assay in the preparation of monoclonal antibodies directed against small cell carcinoma of the lung

1984 • 40 citations

Carboplatin in the Treatment of Small Cell Lung Cancer

1998 • 38 citations

Pharmacological analysis of etoposide in elderly patients with lung cancer.

1999 • 34 citations

Complications of Cancer Chemotherapy

1974 • 34 citations

The Use of Monoclonal Antibodies for the Pathological Diagnosis of Lung Cancer

1986 • 33 citations

Small Cell Carcinoma of the Lung - to Operate or not? Surgical Experience and Results

1986 • 33 citations

Surgical Resection and Adjuvant Chemotherapy for Small Cell Carcinoma

1986 • 32 citations

A Phase II study of all-trans-retinoic acid plus cisplatin and etoposide in patients with extensive stage small cell lung carcinoma

1998 • 31 citations

Immunochemotherapy in 34 cases of oat cell carcinoma of the lung with 19 complete responses.

1977 • 24 citations

Concurrent versus sequential radiotherapy for small cell lung cancer

2001 • 18 citations

A pilot study of MVP (mitomycin-C, vinblastine and cisplatin) chemotherapy in small-cell lung cancer

1998 • 17 citations

Phase II studies of polychemotherapy regimens in small cell lung cancer.

1977 • 16 citations

A Clinico-Pathological Study of Surgical Treatment for Small Cell Carcinoma of the Lung

1986 • 15 citations

Gemcitabine/Carboplatin Versus Cisplatin/Etoposide for Patients With Poor-Prognosis Small Cell Lung Cancer: A Phase III Randomized Trial With Quality-of-Life Evaluation

2001 • 13 citations

A meta-analysis of the role of etoposide (VP16) and cisplatin (CDDP) in small cell lung cancer (SCLC) with a methodology assessment

1999 • 11 citations

Radiation Therapy in the Management of Limited Small Cell Lung Cancer

1998 • 8 citations

A phase II study of paclitaxel (P) and carboplatin (C) as second-line treatment in patients (PTS) with small-cell lung cancer (SCLC)

1999 • 6 citations

Phase II trial of combination chemotherapy with cisplatin, carboplatin and etoposide in stage IIIB and IV small-cell lung cancer

1998 • 6 citations

Weekly Alternating Non-Cross-Resistant Chemotherapy for Small Cell Lung Cancer With a Good Prognosis

1999 • 4 citations

Cisplatin — Paclitaxel — Topotecan (CPT) weekly administration in chemo-naive or pretreated extensive disease small cell lung cancer (ED-SCLC). A SICOG Phase II study

1999 • 3 citations

Paclitaxel/epirubicin/etoposide in patients with extensive-disease small-cell lung cancer (SCLC)

1999 • 2 citations