Multiple defects of the nerve growth factor receptor in human neuroblastomas.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage

1984 • 2,248 citations

In Vitro Cultivation of Human Tumors: Establishment of Cell Lines Derived From a Series of Solid Tumors2

1973 • 2,213 citations

Association of Multiple Copies of the N-mycOncogene with Rapid Progression of Neuroblastomas

1985 • 1,989 citations

Physiology of nerve growth factor.

1980 • 1,602 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

Nerve growth factor receptors on human melanoma cells in culture.

1977 • 670 citations

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene

1988 • 661 citations

Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma

1985 • 644 citations

Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells.

1979 • 627 citations

An immunohistochemical study of the nerve growth factor receptor in developing rats

1988 • 610 citations

Coordinate Morphological and Biochemical Interconversion of Human Neuroblastoma Cells<xref ref-type="fn" rid="FN2">2</xref>

1983 • 544 citations

Viral and cellular fos proteins: A comparative analysis

1984 • 523 citations

Superinduction of c- fos by Nerve Growth Factor in the Presence of Peripherally Active Benzodiazepines

1985 • 478 citations

SPECIAL PATTERN OF WIDESPREAD NEUROBLASTOMA WITH A FAVOURABLE PROGNOSIS

1971 • 404 citations

Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: correlation with N-myc amplification.

1989 • 395 citations

Cytogenetic features of human neuroblastomas and cell lines.

1981 • 386 citations

The Biology and Mechanism of Action of Nerve Growth Factor

1982 • 324 citations

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

1987 • 306 citations

Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene

1985 • 306 citations

Nerve growth factor receptors on PC12 cells: Evidence for two receptor classes with differing cytoskeletal association

1981 • 302 citations

A constitutive promoter directs expression of the nerve growth factor receptor gene.

1988 • 280 citations

Striking paucity of HLA-A, B, C and beta 2-microglobulin on human neuroblastoma cell lines.

1983 • 257 citations

Human neuroblastomas and abnormalities of chromosomes 1 and 17.

1984 • 251 citations

Expression of Functional Nerve Growth Factor Receptors After Gene Transfer

1989 • 235 citations

Nerve growth factor rapidly induces c-fos mRNA in PC12 rat pheochromocytoma cells.

1986 • 220 citations

Molecular biology and genetics of human neuroblastoma

1989 • 184 citations

Neuroblastoma consensus deletion maps to 1p36.1–2

1989 • 172 citations

Nerve growth factor effects and receptors in cultured human neuroblastoma cell lines

1982 • 168 citations

A single Mr approximately 103,000 125I-beta-nerve growth factor-affinity-labeled species represents both the low and high affinity forms of the nerve growth factor receptor.

1986 • 159 citations

Identification of a truncated form of the nerve growth factor receptor.

1988 • 145 citations

Do infants with stage IV-S neuroblastoma need treatment?

1981 • 141 citations

Nerve growth factor receptors on cultured rat Schwann cells

1988 • 131 citations

Nerve growth factor stimulates the hydrolysis of glycosylphosphatidylinositol in PC-12 cells: a mechanism of protein kinase C regulation.

1989 • 126 citations

Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system.

1987 • 117 citations

[3] Assaying binding of nerve growth factor to cell surface receptors

1985 • 102 citations

Biological classification of cell lines derived from human extra-cranial neural tumors.

1988 • 86 citations

Neurotransmitter-synthesizing enzymes in 14 human neuroblastoma cell lines

1981 • 84 citations

Clinical implications of oncogene activation in human neuroblastomas

1986 • 81 citations

Nerve Growth Factor: Mechanism of Action

1980 • 65 citations

Analysis of nerve growth factor receptor expression in human neuroblastoma and neuroepithelioma cell lines.

1989 • 62 citations

Induction of neurite outgrowth in the IMR‐32 human neuroblastoma cell line by nerve growth factor

1981 • 61 citations

Nerve growth factor-induced differentiation of human neuroblastoma and neuroepithelioma cell lines.

1990 • 56 citations

Molecular analysis and clinical significance of N-myc amplification and chromosome 1p monosomy in human neuroblastomas.

1988 • 50 citations

Determination of equilibrium constants and maximum binding capacities in complexIn vitro systems: I. The mammillary system

1965 • 40 citations

Neuroblastoma: inverse relationship between expression of N-myc and NGF-r.

1990 • 21 citations

Nerve growth factor and neural oncology

1983 • 21 citations

Nerve growth factor induces neurite outgrowth in a clone derived from an NGF‐insensitive human neuroblastoma cell line

1989 • 16 citations

v‐src genes stimulate neurite outgrowth in pheochromocytoma (PC12) variants unresponsive to neurotrophic factors

1989 • 16 citations