Communication between myocytes and fibroblasts in cardiac remodeling in angiotensin chimeric mice

A Laboratory manual

1989 • 6,833 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

1998 • 2,570 citations

Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.

1991 • 2,017 citations

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

1993 • 1,420 citations

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.

1991 • 1,358 citations

Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.

1994 • 1,063 citations

Disruption of overlapping transcripts in the ROSA βgeo 26 gene trap strain leads to widespread expression of β-galactosidase in mouse embryos and hematopoietic cells

1997 • 851 citations

Remodeling of the rat right and left ventricles in experimental hypertension.

1990 • 676 citations

Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle.

1989 • 500 citations

The collagen network of the heart.

1979 • 477 citations

Comparative effects of chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on cardiac remodeling after myocardial infarction in the rat.

1994 • 421 citations

Angiotensin II is mitogenic in neonatal rat cardiac fibroblasts.

1993 • 391 citations

Identification of functional angiotensin II receptors on rat cardiac fibroblasts.

1993 • 361 citations

Pressure Overload Induces Cardiac Hypertrophy in Angiotensin II Type 1A Receptor Knockout Mice

1998 • 259 citations

Angiotensin II stimulates the autocrine production of transforming growth factor-β1 in adult rat cardiac fibroblasts

1995 • 256 citations

Characterization of angiotensin II receptors in cultured adult rat cardiac fibroblasts. Coupling to signaling systems and gene expression.

1994 • 243 citations

Angiotensin II Induces Cardiac Phenotypic Modulation and Remodeling In Vivo in Rats

1995 • 242 citations

Significance of Ventricular Myocytes and Nonmyocytes Interaction During Cardiocyte Hypertrophy

1997 • 238 citations

Differential expression of angiotensin receptor 1A and 1B in mouse

1994 • 232 citations

Hormonal and cardiac effects of converting enzyme inhibition in rat myocardial infarction.

1988 • 226 citations

Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat.

1994 • 225 citations

The role of local disparity in conduction and recovery time on ventricular vulnerability to fibrillation

1977 • 170 citations

DNA synthesis in the non-infarcted cardiac interstitium after left coronary artery ligation in the rat: Effects of captopril

1991 • 156 citations

Differential gene expression and regulation of angiotensin II receptor subtypes in rat cardiac fibroblasts and cardiomyocytes in culture.

1994 • 155 citations

Angiotensin-Converting Enzyme Inhibition and Ventricular Remodeling After Myocardial Infarction

1995 • 130 citations

Trophic effects of angiotensin II on neonatal rat cardiac myocytes are mediated by cardiac fibroblasts

1995 • 103 citations

Chimeric mice carrying 'regional' targeted deletion of the angiotensin type 1A receptor gene. Evidence against the role for local angiotensin in the in vivo feedback regulation of renin synthesis in juxtaglomerular cells.

1996 • 101 citations

Coronary Vascular Remodeling and Myocardial Fibrosis in the Rat with Renovascular Hypertension Response to Captopril

1991 • 101 citations

Norepinephrine and ANG II stimulate secretion of TGF-beta by neonatal rat cardiac fibroblasts in vitro

1995 • 96 citations

Arrhythmia susceptibility and myocardial composition in diabetes. Influence of physical conditioning.

1986 • 76 citations

In vitro autoradiographic localization of binding to angiotensin receptors in the rat heart

1990 • 51 citations

Angiotensin II Induced Expression of Transcription Factors Precedes Increase in Transforming Growth Factor-β1 mRNA in Neonatal Cardiac Fibroblasts

1994 • 48 citations

Captopril Modifies Gene Expression in Hypertrophied and Failing Hearts of Aged Spontaneously Hypertensive Rats

1997 • 48 citations

Quantification and localisation of angiotensin II receptors and angiotensin converting enzyme in the developing rat heart

1995 • 27 citations

A novel in vivo mechanism for angiotensin type 1 receptor regulation

1997 • 18 citations

Cardiovascular Health at the Crossroads: Outlook for the 21st Century

1995 • 5 citations