Expression of oligodendrocyte progenitor cell antigens by gliomas: Implications for the histogenesis of brain tumors

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

— Tumors of the Central Nervous System

2013 • 1,787 citations

Specific Genetic Predictors of Chemotherapeutic Response and Survival in Patients With Anaplastic Oligodendrogliomas

1998 • 1,611 citations

Histological Typing of Tumours of the Central Nervous System

1993 • 1,493 citations

Stem Cells in the Central Nervous System

1997 • 1,483 citations

Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor ceil

1988 • 833 citations

Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture

1988 • 760 citations

A role for platelet-derived growth factor in normal gliogenesis in the central nervous system

1988 • 756 citations

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops.

1992 • 689 citations

Co-localization of NG2 proteoglycan and PDGF ?-receptor on O2A progenitor cells in the developing rat brain

1996 • 620 citations

A Classification of the Tumors of the Glioma Group on a Histogenetic Basis with a Correlated Study of Prognosis.

1926 • 595 citations

Improving diagnostic accuracy and interobserver concordance in the classification and grading of primary gliomas

1997 • 552 citations

Tumors of the Central Nervous System

2007 • 409 citations

Differentiation and Death of Premyelinating Oligodendrocytes in Developing Rodent Brain

1997 • 382 citations

Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors.

1992 • 380 citations

Shared Allelic Losses on Chromosomes 1p and 19q Suggest a Common Origin of Oligodendroglioma and Oligoastrocytoma

1995 • 348 citations

A tripotential glial precursor cell is present in the developing spinal cord

1998 • 311 citations

Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells.

1982 • 305 citations

Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop

1995 • 298 citations

Chimeric brains generated by intraventricular transplantation of fetal human brain cells into embryonic rats

1998 • 295 citations

Development and differentiation of glial precursor cells in the rat cerebellum

1993 • 276 citations

PDGF alpha- and beta-receptors activate unique and common signal transduction pathways.

1992 • 259 citations

The primary structure of NG2, a novel membrane-spanning proteoglycan.

1991 • 257 citations

Oligodendroglial progenitors labeled with the O4 antibody persist in the adult rat cerebral cortex in vivo

1997 • 255 citations

Interaction between NG2 proteoglycan and PDGF ?-receptor on O2A progenitor cells is required for optimal response to PDGF

1996 • 236 citations

Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas.

1996 • 228 citations

PDGF receptors on cells of the oligodendrocyte-type-2 astrocyte (O-2A) cell lineage

1989 • 224 citations

The Subependymal Cell Plate (Matrix) and its Relationship to Brain Tumors of the Ependymal Type

1944 • 202 citations

Normal and reactive NG2+ glial cells are distinct from resting and activated microglia

1997 • 186 citations

The NG2 chondroitin sulfate proteoglycan: a multifunctional proteoglycan associated with immature cells.

1996 • 174 citations

Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan.

1996 • 158 citations

Subependymoma: A Newly Recognized Tumor of Subependymal Derivation

1945 • 147 citations

Surface antigens of melanomas and melanocytes defined by mouse monoclonal antibodies: specificity analysis and comparison of antigen expression in cultured cells and tissues.

1985 • 142 citations

Successful chemotherapy for newly diagnosed aggressive oligodendroglioma

1990 • 136 citations

Glial fibrillary acidic protein (GFAP) in oligodendroglial tumors: Gliofibrillary oligodendroglioma and transitional oligoastrocytoma as subtypes of oligodendroglioma

1984 • 130 citations

High frequency of p53 protein accumulation without p53 gene mutation in human juvenile pilocytic, low grade and anaplastic astrocytomas.

1994 • 128 citations

Platelet-derived Growth Factor and Its Receptor Expression in Human Oligodendrogliomas

1998 • 126 citations

Mitotic Activity in the Primate Subependymal Layer and the Genesis of Gliomas

1968 • 114 citations

Participation of the NG2 Proteoglycan in Rat Aortic Smooth Muscle Cell Responses to Platelet-Derived Growth Factor

1995 • 110 citations

Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells.

1991 • 105 citations

The role of the subependymal plate in glial tumorigenesis

1977 • 101 citations

The expression of NG2 proteoglycan in the developing rat limb

1991 • 80 citations

p53 gene mutations in human astrocytic brain tumors including pilocytic astrocytomas

1996 • 66 citations

Uniform lineage of oligodendrogliomas.

1989 • 63 citations

The origin of experimental brain tumours: A sequential study

1976 • 63 citations

ANTIGENIC EXPRESSION BY CELLS DERIVED FROM HUMAN GLIOMAS DOES NOT CORRELATE WITH MORPHOLOGICAL CLASSIFICATION

1987 • 58 citations

Tumors of the Central Nervous System

1994 • 53 citations

From rodent glial precursor cell to human glial neoplasia in the oligodendrocyte‐type‐2‐astrocyte lineage

1995 • 49 citations

Expression of Platelet-Derived Growth Factor Transcripts in Medulloblastomas and Ependymomas

1996 • 39 citations

Glycolipids and myelin proteins in human oligodendrogliomas

1996 • 33 citations

Expression of oligodendrocytic mRNAs in glial tumors: changes associated with tumor grade and extent of neoplastic infiltration.

1997 • 20 citations

Expression of the genes encoding myelin basic protein and proteolipid protein in human malignant gliomas.

1997 • 12 citations

Mixed oligodendroglioma and astrocytoma: Fine structural and immunohistochemical studies of four cases

1988 • 8 citations