Impaired Bone Marrow Microenvironment and Immune Function in T Cell Protein Tyrosine Phosphatase–deficient Mice

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Genomic sequencing.

1984 • 8,343 citations

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1992 • 3,907 citations

A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples.

1993 • 2,807 citations

Further improvements in the plaque technique for detecting single antibody-forming cells.

1968 • 2,171 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

1993 • 756 citations

CD45: An Emerging Role as a Protein Tyrosine Phosphatase Required for Lymphocyte Activation and Development

1994 • 733 citations

The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene.

1995 • 603 citations

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

1993 • 578 citations

Regulation of Hemopoiesis by Bone Marrow Stromal Cells and Their Products

1990 • 546 citations

Recruitment and Activation of PTP1C in Negative Regulation of Antigen Receptor Signaling by FcγRIIB1

1995 • 535 citations

Regulation of T Cell Receptor Signaling by Tyrosine Phosphatase SYP Association with CTLA-4

1996 • 529 citations

Fibronectin and VLA-4 in haematopoietic stem cell–microenvironment interactions

1991 • 522 citations

Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues

1984 • 486 citations

Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

1991 • 471 citations

Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases.

1991 • 433 citations

A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

1991 • 401 citations

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.

1996 • 382 citations

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

1991 • 348 citations

Differential Requirements for α4 Integrins during Fetal and Adult Hematopoiesis

1996 • 347 citations

Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody.

1993 • 345 citations

cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.

1989 • 313 citations

Human Influence on the Atmospheric Vertical Temperature Structure: Detection and Observations

1996 • 289 citations

Guide to techniques in mouse development

1993 • 220 citations

Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor.

1993 • 202 citations

Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases.

1993 • 179 citations

Complementation of the Mitotic Activator, p80 ^cdc25 , by a Human Protein-tyrosine Phosphatase

1990 • 178 citations

Lymphocyte Development from Stem Cells

1992 • 170 citations

COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus.

1995 • 141 citations

Expression of a human T-cell protein-tyrosine-phosphatase in baby hamster kidney cells.

1990 • 132 citations

Microenvironmental organization and stromal cell associations of B lymphocyte precursor cells in mouse bone marrow

1990 • 126 citations

Cloning and characterization of a mouse cDNA encoding a cytoplasmic protein-tyrosine-phosphatase.

1992 • 111 citations

Interleukin-11 stimulates multiple phases of erythropoiesis in vitro

1992 • 95 citations

T cell antigen receptor signaling: Three families of tyrosine kinases and a phosphatase

1994 • 92 citations

Native associations of early hematopoietic stem cells and stromal cells isolated in bone marrow cell aggregates

1994 • 80 citations

A signaling pathway governing early thymocyte maturation

1995 • 76 citations

Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system

1991 • 71 citations

Nuclear localization and cell cycle regulation of a murine protein tyrosine phosphatase.

1994 • 71 citations

Hemolytic anemia in non‐obese diabetic mice

1991 • 60 citations

Two Splice Variants of a Tyrosine Phosphatase Differ in Substrate Specificity, DNA Binding, and Subcellular Location

1996 • 57 citations

Regulation of B-cell activation by CD45: a question of mechanism

1994 • 52 citations

Activation of transcription via AP-1 or CREB regulatory sites is blocked by protein tyrosine phosphatases.

1991 • 44 citations

Abnormal Peripheral Lymphocyte Function in c-ablMutant Mice

1996 • 43 citations

Highly restricted expression of a stromal cell determinant in mouse bone marrow in vivo.

1992 • 42 citations

Stimulation of human bone marrow stromal cell tyrosine kinases and IL-6 production by contact with B lymphocytes.

1995 • 38 citations

Differential Effects of Expression of the CD45 Tyrosine Protein Phosphatase on the Tyrosine Phosphorylation of the lck, fyn, and c-src Tyrosine Protein Kinases

1993 • 35 citations

Genetic Analysis of Tyrosine Kinase Function in B Cell Development

1996 • 34 citations

The Role of Protein Tyrosine Phosphatases in Lymphocyte Activation and Differentiation

1994 • 34 citations

Involvement of Src‐homology‐2‐domain‐containing Protein‐tyrosine Phosphatase 2 in T Cell Activation

1996 • 24 citations

T CELL SUBSETS IN THE THYMUS OF GRAFT-VERSUS-HOST IMMUNOSUPPRESSED MICE: SENSITIVITY OF THE L3T4+LYT-2− SUBSET TO CORTISONE

1991 • 22 citations

Nuclear Localization and Cell Cycle Regulation of a Murine Protein Tyrosine Phosphatase

1994 • 19 citations

Targeting of the T-cell receptor zeta-chain gene in embryonic stem cells: strategies for generating multiple mutations in a single gene.

1992 • 16 citations

B cell Ag receptor mediates different types of signals in the protein kinase activity between immature B cell and mature B cell.

1994 • 16 citations

Structure of the Murine MPTP-PEST Gene: Genomic Organization and Chromosomal Mapping

1995 • 15 citations

Differential intracellular compartmentalization of phosphotyrosine phosphatases in a glial cell line: TC-PTP versus PTP-1B

1993 • 15 citations

Induction of a glucocorticoid-sensitive F1-anti-parental mechanism that affects engraftment during graft-versus-host disease.

1995 • 4 citations