Serine92 (F7) contributes to the control of heme reactivity and stability in myoglobin

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

1970 • 2,874 citations

Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector

1988 • 1,516 citations

Discrimination between Oxygen and Carbon Monoxide and Inhibition of Autooxidation by Myoglobin

1989 • 292 citations

The effects of amino acid substitution at position E7 (residue 64) on the kinetics of ligand binding to sperm whale myoglobin.

1990 • 288 citations

The role of the distal histidine in myoglobin and haemoglobin

1988 • 288 citations

High-resolution study of the three-dimensional structure of horse heart metmyoglobin

1990 • 278 citations

A novel site-directed mutant of myoglobin with an unusually high O2 affinity and low autooxidation rate.

1992 • 212 citations

Analysis of the kinetic barriers for ligand binding to sperm whale myoglobin using site-directed mutagenesis and laser photolysis techniques.

1990 • 183 citations

Distal residues in the oxygen binding site of haemoglobin studied by protein engineering

1987 • 160 citations

Alteration of sperm whale myoglobin heme axial ligation by site-directed mutagenesis

1990 • 120 citations

Preferred orientation of imidazole ligands in metalloporphyrins

1986 • 120 citations

Ligand binding to heme proteins. An evaluation of distal effects.

1983 • 119 citations

The effects of E7 and E11 mutations on the kinetics of ligand binding to R state human hemoglobin

1989 • 107 citations

The kinetics of ligand binding to plant hemoglobins

1989 • 100 citations

Structure of the liganded T state of haemoglobin identifies the origin of cooperative oxygen binding

1988 • 88 citations

Syntheses and NMR characterization of chelated heme models of hemoproteins

1979 • 85 citations

Distal pocket polarity in ligand binding to myoglobin: structural and functional characterization of a threonine68 (E11) mutant

1991 • 78 citations

Absence of water at the sixth co-ordination site in ferric Aplysia myoglobin

1981 • 66 citations

Contributions of residue 45(CD3) and heme-6-propionate to the bimolecular and geminate recombination reactions of myoglobin

1991 • 64 citations

Reactivity of ferric Aplysia myoglobin towards anionic ligands in the acidic region

1981 • 52 citations

The assignment of carbon monoxide association rate constants to the alpha and beta subunits in native and mutant human deoxyhemoglobin tetramers.

1991 • 38 citations

Apomyoglobin as a molecular recognition surface: expression, reconstitution and crystallization of recombinant porcine myoglobin in Escherichia coli

1988 • 26 citations

High-resolution x-ray structures of pig metmyoglobin and two CD3 mutants: Mb(Lys45 .fwdarw. Arg) and Mb(Lys45 .fwdarw. Ser)

1992 • 24 citations

Cyclophane hemes. 3. Magnitudes of distal side steric effects in hemes and hemoproteins

1980 • 22 citations