Ultrastructural cytochemistry of the mammalian cell nucleolus.

Controlled Nucleation for the Regulation of the Particle Size in Monodisperse Gold Suspensions

1973 • 7,933 citations

Controlled silver-staining of nucleolus organizer regions with a protective colloidal developer: a 1-step method

1980 • 2,910 citations

Structure of Chromatin

1977 • 1,276 citations

Communication to the editors

1971 • 917 citations

Enhancement of structural preservation and immunocytochemical staining in low temperature embedded pancreatic tissue.

1981 • 721 citations

The Cell Nucleus

1966 • 522 citations

Protein A‐gold electron microscopic immunocytochemistry: Methods, applications, and limitations

1984 • 493 citations

Two different chromatin structures coexist in ribosomal RNA genes throughout the cell cycle

1989 • 391 citations

The Nucleolar Structure

1976 • 370 citations

Transcriptionally active chromatin

1984 • 361 citations

Localization of RNA polymerase I in interphase cells and mitotic chromosomes by light and electron microscopic immunocytochemistry.

1984 • 313 citations

Effect of tissue processing on colloidal gold cytochemistry.

1987 • 298 citations

Structure of Transcribing Chromatin

1980 • 281 citations

The fine structure of the cancer cell nucleus

1963 • 277 citations

Reversible changes in nucleosome structure and histone H3 accessibility in transcriptionally active and inactive states of rDNA chromatin

1983 • 231 citations

A major nucleolar protein, nucleolin, induces chromatin decondensation by binding to histone Hl

1988 • 216 citations

The efficiency of immunolabel on Lowicryl sections compared to theoretical predictions.

1987 • 189 citations

Ribonucleic Acids in Both Nucleus and Cytoplasm, and the Function of the Nucleolus

1940 • 176 citations

Cytochemical studies on nuclear fine structure*1

1963 • 159 citations

ELECTRON MICROSCOPIC EXAMINATION OF THE SITES OF NUCLEAR RNA SYNTHESIS DURING AMPHIBIAN EMBRYOGENESIS

1965 • 147 citations

Further evidence that phosphoprotein C23 (110 kD/pI 5.1) is the nucleolar silver staining protein

1984 • 133 citations

On the position of nucleolus organizer regions (NORs) in interphase nuclei

1986 • 129 citations

Human autoantibodies: probes for nucleolus structure and function

1987 • 128 citations

In situ hybridization at the electron microscope level: an improved method for precise localization of ribosomal DNA and RNA.

1989 • 119 citations

Association of DNA topoisomerase I and RNA polymerase I: a possible role for topoisomerase I in ribosomal gene transcription

1988 • 113 citations

Does the synthesis of ribosomal RNA take place‐within nucleolar fibrillar centers or dense fibrillar components?

1989 • 110 citations

Simultaneous immunoelectron microscopic visualization of protein B23 and C23 distribution in the HeLa cell nucleolus.

1989 • 103 citations

MODIFICATION OF RIBONUCLEIC ACID SYNTHESIS IN NUCLEI ISOLATED FROM NORMAL AND REGENERATING LIVER: SOME EFFECTS OF SALT AND SPECIFIC DIVALENT CATIONS

1967 • 102 citations

The nucleolar organizer regions.

1983 • 98 citations

High resolution autoradiographic studies of Ehrlich tumour cell nucleoli

1976 • 96 citations

Structure of the active nucleolar chromatin of Xenopus laevis oocytes

1982 • 89 citations

Modulation of Ribosomal RNA Synthesis in Oncopeltus fasciatus: An Electron Microscopic Study of the Relationship between Changes in Chromatin Structure and Transcriptional Activity

1978 • 87 citations

High sensitivity immunolocalization of double and single-stranded DNA by a monoclonal antibody.

1987 • 85 citations

The fine structure of the nucleolus during interphase and mitosis in ehrlich tumour cells cultivated in vitro

1974 • 78 citations

Dehydration and embedding temperatures affect the antigenic specificity of tubulin and immunolabeling by the protein A-colloidal gold technique.

1983 • 74 citations

The intranuclear localization of two DNA-dependent RNA polymerase activities.

1967 • 69 citations

La détection histochimique des acides pentosenucléiques

1940 • 66 citations

Synthesis of a more stable osmium ammine electron-dense DNA stain.

1989 • 65 citations

Relationship between the Ag-NOR proteins and ribosomal chromatin in Situ during drug-induced RNA synthesis inhibition

1984 • 60 citations

The Feulgen-like osmium—ammine reaction as a tool to investigate chromatin structure in thin sections

1982 • 57 citations

Injected histone antibodies interfere with transcription of lampbrush chromosome loops in oocytes of Pleurodeles

1979 • 56 citations

Silver staining of the nucleolar organizer regions (NORs) on Lowicryl and cryo-ultrathin sections.

1985 • 54 citations

Spatial redistribution of ribosomal chromatin in the fibrillar centres of human circulating lymphocytes after stimulation of transcription

1987 • 44 citations

Nucleologenesis in chick erythrocyte nuclei reactivated by cell fusion

1979 • 41 citations

RNA synthesis in the ultrastructural and biochemical components of the nucleolus of Chinese hamster ovary cells.

1975 • 41 citations

STUDIES ON THE ULTRASTRUCTURE OF THE NUCLEOLI OF THE WALKER TUMOR AND RAT LIVER.

1964 • 40 citations

Nucleologenesis in ehrlich tumour cells

1978 • 33 citations

Visualization in situ of extended DNA filaments in nucleolar chromatin of rat hepatocytes

1982 • 32 citations

Identification ultrastructurale de l'organisateur nucléolaire par la technique à l'argent.

1978 • 32 citations

Relations between fibrillar centres and nucleolus-associated chromatin in ehrlich tumour cells

1979 • 30 citations

Relationship between the extended, non-nucleosomal intranucleolar chromatin in situ and ribosomal RNA synthesis

1983 • 29 citations

The nucleolus in telophase, interphase and prophase

1980 • 27 citations

Effect of dehydrating agents on DNA organization in herpes viruses.

1987 • 26 citations

Structural changes of soluble rat liver chromatin induced by the shift in pH from 7 to 9.

1981 • 18 citations

Electron-microscopical evidence that ribosomal chromatin of human circulating lymphocytes is devoid of histones

1985 • 18 citations

Structural organization of rat hepatocyte chromatin as visualized in thin frozen sections selectively stained for DNA.

1984 • 17 citations

Effect of the ionic environment on the transcriptional activity of rat liver nucleoli

1976 • 14 citations

Ultrastructural distribution of histones within Ehrlich tumor cell nucleoli: a cytochemical and immunocytochemical study.

1989 • 14 citations