Measurement of Intracellular Free Zinc in Living Cortical Neurons: Routes of Entry

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

The biochemical basis of zinc physiology

1993 • 2,967 citations

Handbook of fluorescent probes and research chemicals

1996 • 2,829 citations

The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc

1996 • 1,857 citations

Ca2 ⁺ Permeability of KA-AMPA—Gated Glutamate Receptor Channels Depends on Subunit Composition

1991 • 1,458 citations

Glutamate neurotoxicity in cortical cell culture

1987 • 1,400 citations

Effect of anoxia on ion distribution in the brain

1985 • 1,341 citations

Release of endogenous Zn2+ from brain tissue during activity

1984 • 1,125 citations

Neurobiology of Zinc and Zinc-Containing Neurons

1989 • 1,075 citations

The Role of Zinc in Selective Neuronal Death After Transient Global Cerebral Ischemia

1996 • 1,057 citations

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons

1987 • 852 citations

Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels

1991 • 827 citations

Stimulation-induced uptake and release of zinc in hippocampal slices

1984 • 812 citations

ZnT-3, a putative transporter of zinc into synaptic vesicles

1996 • 712 citations

Zinc Selectively Blocks the Action of N -Methyl-D-Aspartate on Cortical Neurons

1987 • 678 citations

Differences in Ca2+ permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression

1994 • 661 citations

Transition Metals in Control of Gene Expression

1993 • 629 citations

A quinoline fluorescence method for visualizing and assaying the histochemically reactive zinc (bouton zinc) in the brain

1987 • 525 citations

Correlation of apoptosis with change in intracellular labile Zn(II) using zinquin [(2-methyl-8-p-toluenesulphonamido-6-quinolyloxy)acetic acid], a new specific fluorescent probe for Zn(II)

1993 • 490 citations

Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+.

1985 • 489 citations

Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc

1994 • 445 citations

Intravesicular localization of zinc in rat telencephalic boutons. A histochemical study

1985 • 410 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.

1992 • 399 citations

Translocation of zinc may contribute to seizure-induced death of neurons

1989 • 347 citations

Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles

1994 • 329 citations

A non‐selective cation conductance in frog muscle membrane blocked by micromolar external calcium ions.

1984 • 305 citations

Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat

1990 • 303 citations

Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons

1990 • 302 citations

Kinetics and mechanism of reactions of main group metal ions with biological carriers

1969 • 290 citations

Zn2+: an endogenous modulator of ligand- and voltage-gated ion channels

1994 • 284 citations

AMPA receptor activation potentiates zinc neurotoxicity

1993 • 280 citations

Video image analysis of labile zinc in viable pancreatic islet cells using a specific fluorescent probe for zinc.

1994 • 273 citations

Disruption of the Metallothionein-III Gene in Mice: Analysis of Brain Zinc, Behavior, and Neuron Vulnerability to Metals, Aging, and Seizures

1997 • 248 citations

Excitation-Transcription Coupling Mediated by Zinc Influx through Voltage-dependent Calcium Channels

1995 • 227 citations

Zinc-Containing Neurons

1994 • 224 citations

Zinc toxicity on cultured cortical neurons: Involvement of N-methyl-d-aspartate receptors

1994 • 223 citations

Agonist-activated cobalt uptake identifies divalent cation—Permeable kainate receptors on neurons and glial cells

1991 • 214 citations

AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h

1993 • 192 citations

Brief exposure to zinc is toxic to cortical neurons

1986 • 182 citations

A selective loss of hippocampal mossy fiber Timm stain accompanies granule cell seizure activity induced by perforant path stimulation

1985 • 179 citations

Imaging free zinc in synaptic terminals in live hippocampal slices

1997 • 167 citations

Expression and regulation of brain metallothionein

1995 • 162 citations

Metallothionein/disulfide interactions, oxidative stress, and the mobilization of cellular zinc

1995 • 160 citations

Intracellular free zinc and zinc buffering in human red blood cells

1991 • 151 citations

Micromolar Ca2+ transients in dendritic spines of hippocampal pyramidal neurons in brain slice

1995 • 143 citations

Characterization of Zinc-Induced Neuronal Death in Primary Cultures of Rat Cerebellar Granule Cells

1997 • 142 citations

Cytotoxicity in Murine Neocortical Cell Culture

1993 • 141 citations

Physiological Roles of the Sodium‐Calcium Exchanger in Nerve and Muscle^a

1991 • 130 citations

External Calcium Ions Are Required for Potassium Channel Gating in Squid Neurons

1987 • 128 citations

Glutamate-induced increases in intracellular free Mg2+ in cultured cortical neurons

1993 • 125 citations

Zn2+ permeates Ca2+permeable AMPA/kainate channels and triggers selective neural injury

1995 • 112 citations

Permeation of Manganese, Cadmium, Zinc, and Beryllium Through Calcium Channels of an Insect Muscle Membrane

1977 • 110 citations

Na⁺—Ca²⁺ Exchange Currents in Cortical Neurons: Concomitant Forward and Reverse Operation and Effect of Glutamate

1997 • 100 citations

Measurement of free Zn2+ ion concentration with the fluorescent probe mag-fura-2 (furaptra)

1993 • 92 citations

Intracellular Zinc Movement and Its Effect on the Carbohydrate Metabolism of Isolated Rat Hepatocytes

1996 • 90 citations

Cortical neurones with Ca2+permeable AMPA/kainate channels display distinct receptor immunoreactivity and are GABAergic

1994 • 64 citations

Cortical neurones exhibiting kainate-activated Co2+uptake are selectively vulnerable to AMPA/kainate receptor-mediated toxicity

1994 • 62 citations

AMPA/Zn2+-induced neurotoxicity in rat primary cortical cultures: involvement of L-type calcium channels

1994 • 55 citations

Role of intracellular free Ca(II) and Zn(II) in dexamethasone‐induced apoptosis and dexamethasone resistance in human leukemic CEM cell lines

1995 • 35 citations

Mn and Cd transport by the Na-Ca exchanger of ferret red blood cells

1991 • 34 citations

Multiple actions of zinc on transmitter release at mouse end-plates

1990 • 33 citations

Methylmercury‐Induced Elevations in Intrasynaptosomal Zinc Concentrations: An ¹⁹F‐NMR Study

1994 • 33 citations

The Na⁺‐Ca²⁺ Exchanger in Rat Brain Synaptosomes

1996 • 32 citations

Characterization of N‐(6‐methoxy‐8‐quinolyl)‐p‐toluenesulfonamide for the detection of zinc in living sperm cells

1995 • 31 citations

Differential control of free calcium and free zinc levels in isolated bovine liver nuclei

1993 • 31 citations

Permeation by zinc of bovine chromaffin cell calcium channels: relevance to secretion

1994 • 27 citations

Evaluation of mag-fura-5, the new fluorescent indicator for free magnesium measurements

1992 • 25 citations

Na+-dependent alkaline earth metal uptake in cardiac sarcolemmal vesicles

1985 • 25 citations