Age-dependent deficits in spatial memory are related to impaired hippocampal kindling.

LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS

1957 • 7,145 citations

Hippocampus, space, and memory

1979 • 2,033 citations

Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat.

1979 • 1,970 citations

Remembrance of places passed: Spatial memory in rats.

1976 • 1,824 citations

Development of Epileptic Seizures through Brain Stimulation at Low Intensity

1967 • 854 citations

Hippocampal connections and spatial discrimination

1978 • 836 citations

Stimulus control of spatial behavior on the eight-arm maze in rats

1980 • 490 citations

Spatial memory deficit in senescent rats.

1980 • 479 citations

Patterns of activation in a monosynaptic cortical pathway: The perforant path input to the dentate area of the hippocampal formation

1971 • 473 citations

Spatial memory and radial arm maze performance of rats

1977 • 392 citations

Blockade of long-term potentiation in rat hippocampal CA1 region by inhibitors of protein synthesis

1984 • 346 citations

Neuroanatomical bases of spatial memory

1980 • 306 citations

Brain cholinergic dysfunction and memory in aged rats

1980 • 257 citations

Animal Models of Declining Memory in the Aged: Short-term and Spatial Memory in the Aged Rat

1980 • 227 citations

Does the Engram of Kindling Model the Engram of Normal Long Term Memory?

1975 • 220 citations

Patterns of Astroglial Hypertrophy and Neuronal Degeneration in the Hippocampus of Aged, Memory-deficient Rats

1977 • 219 citations

Opiate Antagonists Improve Spatial Memory

1983 • 162 citations

Lesion-induced synaptogenesis in the dentate gyrus of aged rats: I. Loss and reacquisition of normal synaptic density

1982 • 161 citations

Presynaptic cholinergic mechanisms in brain of aged rats with memory impairments

1981 • 139 citations

Loss of synapses in the dentate gyrus of the senescent rat

1976 • 130 citations

Compensatory synapse growth in aged animals after neuronal death

1979 • 126 citations

Hippocampal aging in rats: A morphometric study of multiple variables in semithin sections

1981 • 125 citations

Loss of place specificity in hippocampal complex spike cells of senescent rat

1983 • 119 citations

Decrease in the number of synapses in the senescent brain: A quantitative electron microscopic analysis of the dentate gyrus molecular layer in the rat

1976 • 119 citations

Radial-arm maze behavior by rats with dorsal hippocampal lesions: Effects of cuing.

1982 • 117 citations

The nature of thought

1939 • 111 citations

Stability of synaptic density and spine volume in dentate gyrus of aged rats

1983 • 88 citations

Changes in translation of synaptic excitation to dentate granule cell discharge accompanying long-term potentiation. II. An evaluation of mechanisms utilizing dentate gyrus dually innervated by surviving ipsilateral and sprouted crossed temporodentate inputs.

1981 • 74 citations

Effect of Acetoxycycloheximide on Learning and Memory of a Light–Dark Discrimination

1968 • 73 citations

Changes in neurotransmitter actions in the aged rat hippocampus

1982 • 70 citations

Loss of axosomatic synapses in the dentate gyrus of aged rats

1979 • 69 citations

Improvement of 8-arm maze performance in aged fischer 344 rats with 3,4-diaminopyridine

1983 • 69 citations

Activity and excitability to electrical current of cortical auditory receptive neurons of awake cats as affected by stimulus association

1976 • 65 citations

The Nature of Thought

2014 • 64 citations

Memory impairment during prolonged training in mice given inhibitors of cerebral protein synthesis

1973 • 60 citations

Secondary Epileptogenesis in Frog Forebrain: Effect of Inhibition of Protein Synthesis

1975 • 56 citations

Changes in translation of synaptic excitation to dentate granule cell discharge accompanying long-term potentiation. I. Differences between normal and reinnervated dentate gyrus.

1981 • 54 citations

Kindling in the frog: Development of spontaneous epileptiform activity

1976 • 50 citations

Amnesic effect of cycloheximide not due to depletion of a constitutive brain protein with short half-life

1976 • 31 citations

EFFECTS OF ANTIBIOTICS ON LONG-TERM MEMORY FORMATION IN THE GOLDFISH

1971 • 30 citations

Loss of axon terminals contacting neuronal somata in the dentate gyrus of aged rats

1981 • 29 citations