The Primate Lentiviral Receptor Bonzo/STRL33 Is Coordinately Regulated with CCR5 and Its Expression Pattern Is Conserved Between Human and Mouse

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

1996 • 3,106 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1996 • 2,502 citations

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

Human Chemokines: An Update

1997 • 2,235 citations

A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors

1996 • 1,868 citations

The role of a mutant CCR5 allele in HIV–1 transmission and disease progression

1996 • 1,364 citations

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

1997 • 1,124 citations

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1993 • 984 citations

Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

1998 • 918 citations

Defects in Macrophage Recruitment and Host Defense in Mice Lacking the CCR2 Chemokine Receptor

1997 • 700 citations

Expression cloning of new receptors used by simian and human immunodeficiency viruses

1997 • 692 citations

Chemokines, leukocyte trafficking, and inflammation

1994 • 636 citations

HIV Coreceptor Downregulation as Antiviral Principle: SDF-1α–dependent Internalization of the Chemokine Receptor CXCR4 Contributes to Inhibition of HIV Replication

1997 • 564 citations

Antigen-independent activation of naive and memory resting T cells by a cytokine combination.

1994 • 541 citations

Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes.

1996 • 443 citations

Cytokine Signals Are Sufficient for HIV-1 Infection of Resting Human T Lymphocytes

1999 • 428 citations

Identification of CCR6, the Specific Receptor for a Novel Lymphocyte-directed CC Chemokine LARC

1997 • 413 citations

Aminooxypentane-RANTES Induces CCR5 Internalization but Inhibits Recycling: A Novel Inhibitory Mechanism of HIV Infectivity

1998 • 409 citations

CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3 alpha.

1999 • 404 citations

Chemokines and T Lymphocytes

1998 • 403 citations

Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4

1997 • 382 citations

STRL33, A Novel Chemokine Receptor–like Protein, Functions as a Fusion Cofactor for Both Macrophage-tropic and T Cell Line–tropic HIV-1

1997 • 378 citations

CC-Chemokine Receptor 6 Is Expressed on Diverse Memory Subsets of T Cells and Determines Responsiveness to Macrophage Inflammatory Protein 3α

1999 • 345 citations

Lymphocyte-specific chemokine receptor CXCR3: regulation, chemokine binding and gene localization

1998 • 340 citations

Chemokine receptors: Structure, function and role in microbial pathogenesis

1996 • 329 citations

Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses

1997 • 312 citations

Chemokine Receptor Responses on T Cells Are Achieved Through Regulation of Both Receptor Expression and Signaling

1999 • 281 citations

Impaired Macrophage Function and Enhanced T Cell-Dependent Immune Response in Mice Lacking CCR5, the Mouse Homologue of the Major HIV-1 Coreceptor

1998 • 252 citations

CCR2 Expression Determines T1 Versus T2 Polarization During Pulmonary Cryptococcus neoformans Infection

2000 • 237 citations

HIV-1 Coreceptor Activity of CCR5 and Its Inhibition by Chemokines: Independence from G Protein Signaling and Importance of Coreceptor Downmodulation

1997 • 214 citations

Identification of CCR8, the Receptor for the Human CC Chemokine I-309

1997 • 198 citations

Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity

1997 • 176 citations

The autocrine production of transforming growth factor-beta 1 during lymphocyte activation. A study with a monoclonal antibody-based ELISA.

1990 • 169 citations

IL-4 induces functional cell-surface expression of CXCR4 on human T cells.

1998 • 169 citations

Expression of monocyte chemoattractant protein‐1 and interleukin‐8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential

1996 • 169 citations

Cutting Edge: Role of C-C Chemokine Receptor 5 in Organ-Specific and Innate Immunity toCryptococcus neoformans

1999 • 168 citations

Dual effect of interleukin 4 on HIV-1 expression: Implications for viral phenotypic switch and disease progression

1998 • 152 citations

Differential regulation of CXCR4 and CCR5 endocytosis

1998 • 146 citations

Cutting Edge: IL-4 Induces Functional Cell-Surface Expression of CXCR4 on Human T Cells

1998 • 139 citations

IL-15 Induces the Expression of Chemokines and Their Receptors in T Lymphocytes

1999 • 119 citations

The Genes Encoding the Human CC-Chemokine Receptors CC-CKR1 to CC-CKR5 (CMKBR1–CMKBR5) Are Clustered in the p21.3–p24 Region of Chromosome 3

1996 • 104 citations

Cloning, Expression, and Chromosomal Mapping of a Novel Human CC-Chemokine Receptor (CCR10) That Displays High-Affinity Binding for MCP-1 and MCP-3

1997 • 101 citations

The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues

1995 • 98 citations

IL-4 and a glucocorticoid up-regulate CXCR4 expression on human CD4+ T lymphocytes and enhance HIV-1 replication

1998 • 97 citations

Functional analysis of human T cell subsets defined by CD45 isoform expression.

1992 • 89 citations

TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function

1997 • 88 citations

Eotaxin Activates T Cells to Chemotaxis and Adhesion Only if Induced to Express CCR3 by IL-2 Together with IL-4

1999 • 80 citations

Receptor-mediated Endocytosis of CC-chemokines

1997 • 80 citations

G protein-coupled receptors in HIV and SIV entry: New perspectives on lentivirus–host interactions and on the utility of animal models

1998 • 74 citations

Structural interactions between chemokine receptors, gp120 Env and CD4

1998 • 55 citations

The β-Chemokine Receptor Genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) Cluster within 285 kb on Human Chromosome 3p21

1997 • 34 citations