Bronchial biopsies and airway inflammation

Damage of the Airway Epithelium and Bronchial Reactivity in Patients with Asthma

1985 • 1,315 citations

Cellular Events in the Bronchi in Mild Asthma and after Bronchial Provocation

1989 • 1,158 citations

SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS

1989 • 1,151 citations

THE PATHOLOGY OF ASTHMA, WITH SPECIAL REFERENCE TO CHANGES IN THE BRONCHIAL MUCOSA

1960 • 1,014 citations

Identification of Activated T Lymphocytes and Eosinophils in Bronchial Biopsies in Stable Atopic Asthma

1990 • 890 citations

Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines.

1994 • 850 citations

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.

1991 • 841 citations

A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema

1969 • 704 citations

Myofibroblasts and Subepithelial Fibrosis in Bronchial Asthma

1990 • 670 citations

Effect of an Inhaled Corticosteroid on Airway Inflammation and Symptoms in Asthma

1992 • 654 citations

A comparative study of the effects of an inhaled corticosteroid, budesonide, and a β2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: A randomized, double-blind, parallel-group controlled trial

1992 • 595 citations

Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia.

1992 • 572 citations

Effects of Treatment on Airway Inflammation and Thickening of Basement Membrane Reticular Collagen in Asthma: A Quantitative Light and Electron Microscopic Study

1992 • 548 citations

Airway Mucosal Inflammation Even in Patients with Newly Diagnosed Asthma

1993 • 543 citations

Airway eosinophilia in chronic bronchitis during exacerbations.

1994 • 537 citations

Identification of T lymphocytes, Macrophages, and Activated Eosinophils in the Bronchial Mucosa in Intrinsic Asthma: Relationship to Symptoms and Bronchial Responsiveness

1992 • 414 citations

IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity.

1996 • 413 citations

Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease

1993 • 408 citations

Anti-inflammatory effects of low-dose oral theophylline in atopic asthma

1994 • 405 citations

Activated T-Lymphocytes and Macrophages in Bronchial Mucosa of Subjects with Chronic Bronchitis

1993 • 387 citations

Intraluminal Airway Inflammation in Chronic Bronchitis: Characterization and Correlation with Clinical Parameters

1989 • 377 citations

Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma.

1995 • 355 citations

Increases in Activated T Lymphocytes, Eosinophils, and Cytokine mRNA Expression for Interleukin-5 and Granulocyte/Macrophage Colony-stimulating Factor in Bronchial Biopsies after Allergen Inhalation Challenge in Atopic Asthmatics

1993 • 336 citations

Quantitative Structural Analysis of Peripheral Airways and Arteries in Sudden Fatal Asthma

1991 • 321 citations

Placebo-controlled immunopathologic study of four months of inhaled corticosteroids in asthma.

1994 • 317 citations

Bronchoalveolar Neutrophilia during Late Asthmatic Reactions Induced by Toluene Diisocyanate

1987 • 309 citations

Comparison of leukocyte counts in sputum, bronchial biopsies, and bronchoalveolar lavage.

1995 • 278 citations

Immunomodulation by theophylline in asthma. Demonstration by withdrawal of therapy.

1995 • 268 citations

Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa.

1996 • 266 citations

Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids.

1996 • 246 citations

Characteristics of the Inflammation in Biopsies from Large Airways of Subjects with Asthma and Subjects with Chronic Airflow Limitation

1992 • 238 citations

Bronchial biopsy evidence for leukocyte infiltration and upregulation of leukocyte-endothelial cell adhesion molecules 6 hours after local allergen challenge of sensitized asthmatic airways.

1994 • 227 citations

Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis.

1994 • 226 citations

Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma

1992 • 224 citations

Reassessment of inflammation of airways in chronic bronchitis.

1985 • 217 citations

Effect of smoking cessation on airway inflammation in chronic bronchitis.

1995 • 210 citations

Bronchial Biopsy in Chronic Bronchitis and Asthma

1960 • 200 citations

Expression of endothelial and leukocyte adhesion molecules intercellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma

1993 • 189 citations

Airway Mucosal Inflammation in Occupational Asthma Induced by Toluene Diisocyanate

1992 • 181 citations

Airflow limitation in chronic bronchitis is associated with T-lymphocyte and macrophage infiltration of the bronchial mucosa.

1996 • 177 citations

T Lymphocytes and Activated Eosinophils in Airway Mucosa in Fatal Asthma and Cystic Fibrosis

1992 • 175 citations

Detection of Cytokines and Their Cell Sources in Bronchial Biopsy Specimens From Asthmatic Patients

1994 • 166 citations

The Safety Aspects of Fiberoptic Bronchoscopy, Bronchoalveolar Lavage, and Endobronchial Biopsy in Asthma

1991 • 166 citations

Increased interleukin-10 messenger RNA expression in atopic allergy and asthma.

1996 • 158 citations

Workshop summary and guidelines: Investigative use of bronchoscopy, lavage, and bronchial biopsies in asthma and other airway diseases

1991 • 154 citations

Some histological changes in chronic bronchitis and asthma

1968 • 147 citations

Expression of RANTES by human bronchial epithelial cells in vitro and in vivo and the effect of corticosteroids.

1996 • 133 citations

Intraepithelial T-Lymphocyte Subsets in the Airways of Normal Subjects and of Patients with Chronic Bronchitis

1989 • 118 citations

Effect of Cessation of Exposure to Toluene Diisocyanate (TDI) on Bronchial Mucosa of Subjects with TDI-induced Asthma

1992 • 116 citations

Leucocyte-endothelial adhesion molecules and their role in bronchial asthma and allergic rhinitis

1993 • 111 citations

Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms.

1996 • 98 citations

Cytokines. 3. Cytokines in asthma.

1993 • 95 citations

Comparative Morphology of the Airways in Asthma and Chronic Obstructive Pulmonary Disease

1994 • 94 citations

Pathology of asthma

1992 • 93 citations

Effects of theophylline on inflammatory cells and cytokines in asthmatic subjects: a placebo-controlled parallel group study

1996 • 69 citations

Dynamics of eosinophil infiltration in the bronchial mucosa before and after the late asthmatic reaction

1993 • 64 citations

Investigative use of bronchoscopy, lavage and bronchial biopsies in asthma and other airways diseases

1992 • 62 citations

The histological changes in transbronchial biopsy after treatment of acute lung rejection in heart‐lung transplants

1990 • 49 citations

Intrasubject variability in airway inflammation in biopsies in mild to moderate stable asthma.

1996 • 48 citations

Airway inflammation after removal from the causal agent in occupational asthma due to high and low molecular weight agents

1994 • 47 citations

294 Eosinophils, T-lymphocytes, mast cells, neutrophils and macrophages in bronchial biopsies from atopic asthmatics: Comparison with atopic non-asthma and relationship to bronchial hyperresponsiveness

1991 • 45 citations

Bronchial brush biopsies for studies of epithelial inflammation in stable asthma and nonobstructive chronic bronchitis

1996 • 31 citations

Scanning electron microscopic studies of bronchial mucosa before and during treatment with beclomethasone dipropionate inhalations.

1977 • 28 citations

Anti-inflammatory effects of inhaled beclomethasone dipropionate in nonatopic asthmatics

1996 • 24 citations

Inflammation and bronchial hyperresponsiveness in allergic asthma and chronic obstructive pulmonary disease

1993 • 13 citations

Inflammation and bronchial hyperresponsiveness in allergic asthma and chronic obstructive pulmonary disease

1993 • 3 citations