Keratin-Dependent, Epithelial Resistance to Tumor Necrosis Factor-Induced Apoptosis

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

INTERMEDIATE FILAMENTS: Structure, Dynamics, Function and Disease

1994 • 1,408 citations

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)

1995 • 1,103 citations

A T cell-dependent experimental liver injury in mice inducible by concanavalin A.

1992 • 1,041 citations

The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family

1995 • 990 citations

Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

1997 • 937 citations

FAP-1: A Protein Tyrosine Phosphatase That Associates with Fas

1995 • 702 citations

Tumour necrosis factor alpha in stool as a marker of intestinal inflammation

1992 • 700 citations

Cytokines in intestinal inflammation: Pathophysiological and clinical considerations

1994 • 607 citations

Caspase Cleavage of Keratin 18 and Reorganization of Intermediate Filaments during Epithelial Cell Apoptosis

1997 • 596 citations

Rapid colormetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lymphokines

1984 • 561 citations

Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

1995 • 535 citations

T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6.

1994 • 519 citations

Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models.

1995 • 493 citations

In vitro and in vivo association of transforming growth factor-beta 1 with hepatic fibrosis.

1989 • 420 citations

Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy

1992 • 395 citations

Role of Proinflammatory Cytokines in Acetaminophen Hepatotoxicity

1995 • 322 citations

Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice.

1994 • 304 citations

Induction of cell death by tumour necrosis factor (TNF) receptor 2,CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF

1999 • 286 citations

Mid-gestational lethality in mice lacking keratin 8.

1993 • 247 citations

Lessons from Keratin 18 Knockout Mice: Formation of Novel Keratin Filaments, Secondary Loss of Keratin 7 and Accumulation of Liver-specific Keratin 8-Positive Aggregates

1998 • 205 citations

Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site.

1997 • 183 citations

In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

1997 • 176 citations

Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB

1997 • 168 citations

Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant.

1995 • 161 citations

Histopathology of Acetaminophen-Induced Liver Changes: Role of Interleukin 1α and Tumor Necrosis Factor α

1996 • 161 citations

Oncogenic regulation and function of keratins 8 and 18

1996 • 157 citations

Regulated expression of vimentin cDNA in cells in the presence and absence of a preexisting vimentin filament network.

1990 • 144 citations

Oncogenic Neu/ErbB-2 Increases Ets, AP-1, and NF-kB-dependent Gene Expression, and Inhibiting Ets Activation Blocks Neu-mediated Cellular Transformation

1996 • 127 citations

Susceptibility to hepatotoxicity in transgenic mice that express a dominant-negative human keratin 18 mutant.

1996 • 124 citations

Posttranslational Regulation of Keratins: Degradation of Mouse and Human Keratins 18 and 8

1989 • 121 citations

Identification and immunoprecipitation of cytoskeletal proteins from murine extra-embryonic endodermal cells.

1981 • 107 citations

Simple epithelium keratins are required for maintenance of hepatocyte integrity.

1997 • 106 citations

Intermediate filament proteins of the liver: Emerging disease association and functions

1997 • 89 citations

Protein phosphatase inhibition in normal and keratin 8/18 assembly-incompetent mouse strains supports a functional role of keratin intermediate filaments in preserving hepatocyte integrity

1998 • 75 citations

THE INACTIVATION OF INSULIN

1935 • 11 citations