Asthma, inflammation, eosinophils and bronchial hyperresponsiveness

Eosinophilic Inflammation in Asthma

1990 • 2,535 citations

Damage of the Airway Epithelium and Bronchial Reactivity in Patients with Asthma

1985 • 1,315 citations

Cellular Events in the Bronchi in Mild Asthma and after Bronchial Provocation

1989 • 1,158 citations

SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS

1989 • 1,151 citations

Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions.

1985 • 1,065 citations

Bronchial Biopsies in Asthma: An Ultrastructural, Quantitative Study and Correlation with Hyperreactivity

1989 • 973 citations

Eosinophils and Mast Cells in Bronchoalveolar Lavage in Subjects with Mild Asthma: Relationship to Bronchial Hyperreactivity

1988 • 905 citations

Identification of Activated T Lymphocytes and Eosinophils in Bronchial Biopsies in Stable Atopic Asthma

1990 • 890 citations

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.

1991 • 841 citations

Myofibroblasts and Subepithelial Fibrosis in Bronchial Asthma

1990 • 670 citations

Analysis of proteins and respiratory cells obtained from human lungs by bronchial lavage.

1974 • 654 citations

Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma

1988 • 635 citations

Bronchoalveolar Cell Profiles of Asthmatic and Nonasthmatic Subjects

1987 • 480 citations

EFFECTS OF INHALED PLATELET ACTIVATING FACTOR ON PULMONARY FUNCTION AND BRONCHIAL RESPONSIVENESS IN MAN

1986 • 478 citations

Quantitation of Mast Cells and Eosinophils in the Bronchial Mucosa of Symptomatic Atopic Asthmatics and Healthy Control Subjects Using Immunohistochemistry

1990 • 463 citations

Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: A comparison between budesonide and terbutaline

1985 • 458 citations

Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects

1991 • 448 citations

Effect of long-term treatment with inhaled corticosteroids and beta-agonists on the bronchial responsiveness in children with asthma

1987 • 435 citations

Inhibition of Exercise-Induced Bronchoconstriction by MK-571, a Potent Leukotriene D₄–Receptor Antagonist

1990 • 405 citations

Total Eosinophil Counts in the Management of Bronchial Asthma

1975 • 397 citations

Eosinophils, bronchial hyperreactivity and late‐phase asthmatic reactions

1985 • 348 citations

Morphological studies of bronchial mucosal biopsies from asthmatics before and after ten years of treatment with inhaled steroids

1988 • 341 citations

Inflammatory Cells and Eosinophilic Activity in Asthmatics Investigated by Bronchoalveolar Lavage: The Effects of Antiasthmatic Treatment with Budesonide or Terbutaline

1990 • 300 citations

DEPOSITS OF EOSINOPHIL GRANULE PROTEINS IN CARDIAC TISSUES OF PATIENTS WITH EOSINOPHILIC ENDOMYOCARDIAL DISEASE

1987 • 291 citations

Endothelial cell leukotriene C4 synthesis results from intercellular transfer of leukotriene A4 synthesized by polymorphonuclear leukocytes.

1986 • 283 citations

Leukocytes and Mediators in Bronchoalveolar Lavage during Allergen-induced Late-phase Asthmatic Reactions

1989 • 282 citations

Bronchoalveolar mast cells in extrinsic asthma: a mechanism for the initiation of antigen specific bronchoconstriction.

1985 • 254 citations

Nonspecific Bronchial Reactivity and Its Relationship to the Clinical Expression of Asthma: A Longitudinal Study

1989 • 237 citations

Inhaled Corticosteroids Reduce the Severity of Bronchial Hyperresponsiveness in Asthma, But Oral Theophylline Does Not

1987 • 216 citations

The Eosinophil in Health and Disease.

1981 • 204 citations

Cellular and biochemical characteristics of bronchoalveolar lavage fluid in symptomatic nonallergic asthma

1991 • 200 citations

Human Eosinophil Major Basic Protein Causes Hyperreactivity of Respiratory Smooth Muscle: Role of the Epithelium

1988 • 199 citations

Abnormalities in Airway Smooth Muscle in Fatal Asthma

1990 • 195 citations

Mast cells in bronchoalveolar lumen of patients with bronchial asthma.

1984 • 188 citations

Effect of therapy on bronchial hyperresponsiveness in the long‐term management of asthma

1988 • 166 citations

Allergen-induced Asthmatic Responses: Relationship Between Increases in Airway Responsiveness and Increases in Circulating Eosinophils, Basophils, and Their Progenitors

1991 • 165 citations

Peripheral blood eosinophil counts and bronchial responsiveness.

1987 • 161 citations

Inflammatory Markers in Bronchoalveolar Lavage and in Bronchial Biopsy in Asthma during Remission

1990 • 144 citations

Blood eosinophil number and activity in relation to lung function in patients with asthma and with eosinophilia

1991 • 142 citations

Diagnostic Significance of Increased Bronchoalveolar Lavage Fluid Eosinophils

1990 • 140 citations

Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses

1988 • 136 citations

Variations of Blood Eosinophils and Eosinophil Cationic Protein in Serum in Patients with Bronchial Asthma

1978 • 133 citations

The Effect of Inhaled Corticosteroids on the Maximal Degree of Airway Narrowing to Methacholine in Asthmatic Subjects

1991 • 128 citations

Eosinophilic Airway Inflammation during Exacerbation of Asthma and Its Treatment with Inhaled Corticosteroid

1991 • 127 citations

Eosinophils. A comprehensive review and guide to the scientific and medical literature

1989 • 123 citations

Eosinophils stimulate fibroblast DNA synthesis

1987 • 120 citations

The Eosinophil Component of the Alveolitis in Idiopathic Pulmonary Fibrosis: Signs of Eosinophil Activation in the Lung Are Related to Impaired Lung Function

1989 • 117 citations

Morphological integrity of the bronchial epithelium in mild asthma.

1990 • 112 citations

Generation of leukotrienes by human monocytes upon stimulation of their beta-glucan receptor during phagocytosis.

1985 • 110 citations

In vitro responses of airways from an asthmatic patient.

1987 • 102 citations

Bronchial Hyperresponsiveness in Asthmatic Children

1989 • 98 citations

Inflammatory cells in the airways in mild asthma.

1988 • 93 citations

Decreased leukotriene B4 synthesis in smokers' alveolar macrophages in vitro.

1986 • 91 citations

Bronchoalveolar Lavage and Morphology of the Airways after Cessation of Exposure in Asthmatic Subjects Sensitized to Toluene Diisocyanate

1990 • 89 citations

Changes in bronchial responsiveness to histamine at intervals after allergen challenge.

1987 • 88 citations

Eosinophil activation in the lung is related to lung damage in adult respiratory distress syndrome.

1987 • 66 citations

Epithelial augmentation of trachealis contraction caused by major basic protein of eosinophils

1989 • 64 citations

Lymphocyte subsets in bronchoalveolar lavage fluid obtained from stable asthmatics, and their correlations with bronchial responsiveness

1989 • 61 citations

Eosinophilic lung disease: immunological studies of blood and alveolar eosinophils.

1986 • 56 citations

The relationship between bronchial immunopathology and hyperresponsiveness in asthma

1990 • 54 citations

Effect of racemic ibuprofen dose on the magnitude and duration of platelet cyclo‐oxygenase inhibition: relationship between inhibition of thromboxane production and the plasma unbound concentration of S(+)‐ ibuprofen.

1991 • 53 citations

Chronic eosinophilic pneumonia

1986 • 53 citations

Effect of an inhaled corticosteroid on methacholine airway reactivity

1981 • 44 citations

Ultrastructural and immunohistochemical evidence for release of eosinophilic granules in vivo: Cytotoxic potential in chronic eosinophilic pneumonia

1987 • 43 citations

A freeze-fracture study of human bronchial epithelium in normal, bronchitic and asthmatic subjects.

1988 • 43 citations

Quantitation of Mast Cells and Eosinophils in the Bronchial Mucosa of Symptomatic Atopic Asthmatics and Healthy Control Subjects Using Immunohistochemistry

1991 • 42 citations

Charcot-Leyden crystals and Curschmann spirals in asthmatic sputum.

1986 • 41 citations

The effects of drugs on Sephadex‐induced eosinophilia and lung hyper‐responsiveness in the rat

1990 • 38 citations

Active sensitization of guinea-pig airways in vivo enhances in vivo and in vitro responsiveness

1988 • 35 citations

Release of leukotriene C4 (LTC4) from human eosinophils following adherence to IgE- and IgG-coated schistosomula of Schistosoma mansoni.

1990 • 34 citations

Comparison of whole-blood eosinophil counts in extrinsic asthmatics with acute and chronic asthma.

1982 • 33 citations

Cellular Infiltrates in Asthma and in Chronic Obstructive Pulmonary Disease

1991 • 29 citations

Effect of inhaled beclomethasone dipropionate on bronchial hyperreactivity in asthmatic children during maximal allergen exposure

1991 • 27 citations

The Effect of Beclomethasone Diproprionate on Bronchial Hyperreactivity

1982 • 26 citations

Bronchial hyperresponsiveness : normal and abnormal control, assessment, and therapy

1987 • 24 citations

Lymphocytes in asthma

1991 • 18 citations

Topical Steroid Treatment for Asthma and Rhinitis.

1981 • 17 citations

The Increased Responsiveness to Inhaled Methacholine in Asthma: Combination of Causative Factors

1991 • 8 citations