History assignment: when was the mitochondrion founded?

Molecular chaperones in cellular protein folding

1996 • 3,540 citations

Bacterial evolution

1987 • 2,303 citations

Symbiosis in cell evolution

1981 • 1,386 citations

Evolutionary relationship of archaebacteria, eubacteria, and eukaryotes inferred from phylogenetic trees of duplicated genes.

1989 • 906 citations

Kingdom protozoa and its 18 phyla

1993 • 860 citations

Evolution of the vacuolar H+-ATPase: implications for the origin of eukaryotes.

1989 • 776 citations

The Early Evolution of Eukaryotes: A Geological Perspective

1992 • 673 citations

Monophyletic Origins of the Metazoa: an Evolutionary Link with Fungi

1993 • 673 citations

An ancestral mitochondrial DNA resembling a eubacterial genome in miniature

1997 • 633 citations

Mitochondrial origins.

1985 • 606 citations

Determining Divergence Times of the Major Kingdoms of Living Organisms with a Protein Clock

1996 • 584 citations

Evidence from 18 S Ribosomal DNA that the Lophophorates Are Protostome Animals

1995 • 557 citations

Animals and fungi are each other's closest relatives: congruent evidence from multiple proteins.

1993 • 551 citations

The Chromophyte Algae: Problems and Perspectives

1990 • 483 citations

Megascopic Eukaryotic Algae from the 2.1-Billion-Year-Old Negaunee Iron-Formation, Michigan

1992 • 452 citations

Review Article: The hydrogenosome

1993 • 423 citations

Paracoccus denitrificans and the evolutionary origin of the mitochondrion

1975 • 370 citations

Alpha-tubulin from early-diverging eukaryotic lineages and the evolution of the tubulin family

1996 • 317 citations

A common evolutionary origin for mitochondria and hydrogenosomes.

1996 • 308 citations

A mitochondrial-like chaperonin 60 gene in Giardia lamblia: Evidence that diplomonads once harbored an endosymbiont related to the progenitor of mitochondria

1998 • 288 citations

Direct evidence for secondary loss of mitochondria in Entamoeba histolytica.

1995 • 287 citations

Ribosomal RNA sequences of Sarcocystis muris, Theileria annulata and Crypthecodinium cohnii reveal evolutionary relationships among apicomplexans, dinoflagellates, and ciliates

1991 • 280 citations

The root of the universal tree and the origin of eukaryotes based on elongation factor phylogeny.

1996 • 274 citations

Proterozoic and early Cambrian protists: evidence for accelerating evolutionary tempo.

1994 • 253 citations

Evidence for loss of mitochondria in Microsporidia from a mitochondrial-type HSP70 in Nosema locustae1Note: Nucleotide sequence data reported in this paper has been submitted to the GenBank™ data base under the accession number U97520.1

1997 • 244 citations

Small subunit ribosomal RNA+ of Hexamita inflata and the quest for the first branch in the eukaryotic tree

1993 • 227 citations

Phylogenetic Analysis of β-Tubulin Sequences from Amitochondrial Protozoa

1996 • 217 citations

Presence of a mitochondrial-type 70-kDa heat shock protein inTrichomonas vaginalissuggests a very early mitochondrial endosymbiosis in eukaryotes

1996 • 191 citations

A possible mitochondrial gene in the early-branching amitochondriate protist Trichomonas vaginalis

1996 • 172 citations

Molecular data suggest an early acquisition of the mitochondrion endosymbiont

1996 • 164 citations

Molecular phylogeny of the free-living archezoanTrepomonas agilis and the nature of the first eukaryote

1996 • 119 citations

16S-like rDNA sequences from Developayella elegans, Labyrinthuloides haliotidis, and Proteromonas lacertae confirm that the stramenopiles are a primarily heterotrophic group

1996 • 116 citations

Early origin of foraminifera suggested by SSU rRNA gene sequences

1996 • 109 citations

The nature of the last universal ancestor and the root of the tree of life, still open questions

1992 • 108 citations

Protein phylogeny of translation elongation factor EF-1α suggests microsporidians are extremely ancient eukaryotes

1996 • 108 citations

Evidence for the smallest nuclear genome (2.9 Mb) in the microsporidium Encephalitozoon cuniculi

1995 • 96 citations

Early Cambrian Foraminifera from West Africa

1991 • 92 citations

Molecular analysis of the endosymbionts of tsetse flies: 16S rDNA locus and over‐expression of a chaperonin

1995 • 87 citations

Evolution of Life: fossils, molecules, and culture

1991 • 81 citations

The kingdom Chromista.

1989 • 80 citations

Origin and early evolution of eukaryotes inferred from the amino acid sequences of translation elongation factors 1?/Tu and 2/G

1996 • 74 citations

On small genomes in eukaryotic organisms: molecular karyotypes of two microsporidian species (Protozoa) parasites of vertebrates.

1994 • 74 citations

Evidence for the early divergence of tryptophanyl- and tyrosyl-tRNA synthetases

1997 • 70 citations

The unusually long small subunit ribosomal RNA ofPhreatamoeba balamuthi

1994 • 65 citations

Phylogenetic relationships between the Acantharea and the Polycystinea: A molecular perspective on Haeckel’s Radiolaria

1997 • 64 citations

Hydrogenosomes in the anaerobic fungus Neocallimastix frontalis have a double membrane but lack an associated organelle genome

1997 • 61 citations

The Evolution of Cells

1991 • 59 citations

Ancestral relationships of the major eukaryotic lineages.

1996 • 48 citations

Molecular Chaperon Produced by an Intracellular Symbiont1

1991 • 47 citations

Phylogenetic Position of Amblyospora Hazard & Oldacre (Microspora: Amblyosporidae) Based on Small Subunit rRNA Data and Its Implication for the Evolution of the Microsporidia

1997 • 45 citations

scsB, a cDNA encoding the hydrogenosomal β subunit of succinyl-CoA synthetase from the anaerobic fungus Neocallimastix frontalis

1996 • 29 citations

The age of the common ancestor of eukaryotes and prokaryotes: statistical inferences

1997 • 26 citations

Elevated levels of stress proteins associated with bacterial symbiosis in Amoeba proteus and soybean root nodule cells

1991 • 26 citations