Light chain phosphorylation regulates the movement of smooth muscle myosin on actin filaments.

Regulation and Kinetics of the Actin-Myosin-ATP Interaction

1980 • 1,077 citations

Myosin Phosphorylation and the Cross-Bridge Cycle in Arterial Smooth Muscle

1981 • 705 citations

Movement of myosin-coated fluorescent beads on actin cables in vitro

1983 • 502 citations

Purification and characterization of smooth muscle myosin light chain kinase.

1981 • 501 citations

Conformational transition accompanying the binding of calcium(2+) ion to the protein activator of 3',5'-cyclic adenosine monophosphate phosphodiesterase

1977 • 472 citations

Muscle Contraction and Free Energy Transduction in Biological Systems

1985 • 446 citations

ADP dissociation from actomyosin subfragment 1 is sufficiently slow to limit the unloaded shortening velocity in vertebrate muscle.

1985 • 410 citations

Thin Filament Proteins and Thin Filament-Linked Regulation of Vertebrate Muscle Contractio

1984 • 409 citations

Effect of phosphorylation of smooth muscle myosin on actin activation and Ca2+ regulation.

1977 • 302 citations

Structure and Function of Chicken Gizzard Myosin1

1978 • 265 citations

Reversible phosphorylation of smooth muscle myosin, heavy meromyosin, and platelet myosin.

1981 • 259 citations

Comparison of the myosin and actomyosin ATPase mechanisms of the four types of vertebrate muscles

1980 • 250 citations

Roles of calcium and phosphorylation in the regulation of the activity of gizzard myosin

1978 • 244 citations

Inhibition of smooth muscle actin-activated myosin Mg2+-ATPase activity by caldesmon.

1984 • 243 citations

Regulation of the actin-myosin interaction in vertebrate smooth muscle: Activation via a myosin light-chain kinase and the effect of tropomyosin

1977 • 205 citations

The binding of smooth muscle heavy meromyosin to actin in the presence of ATP. Effect of phosphorylation.

1982 • 157 citations

Myosin filaments have non-phosphorylated light chains in relaxed smooth muscle

1981 • 155 citations

Regulation of myosin light chain and phosphorylase phosphorylation in tracheal smooth muscle.

1982 • 140 citations

Phosphorylation of Smooth Muscle Myosin: Evidence for Cooperativity Between the Myosin Heads

1981 • 136 citations

ATP-dependent movement of myosin in vitro: characterization of a quantitative assay.

1984 • 121 citations

Reversible phosphorylation and dephosphorylation of the 20,000-dalton light chain of myosin during the contraction-relaxation-contraction cycle of arterial smooth muscle.

1980 • 110 citations

Phosphorylation of the 20,000-dalton light chain of myosin of intact arterial smooth muscle in rest and in contraction.

1979 • 100 citations

Distribution of alpha-actinin in single isolated smooth muscle cells

1983 • 96 citations

Phosphorylation-dependent activated tension in skinned gizzard muscle fibers in the absence of Ca2+.

1982 • 91 citations

Ca2+ can affectV max without changes in myosin light chain phosphorylation in smooth muscle

1984 • 85 citations

Electron microscopy of synthetic myosin filaments. Evidence for cross-bridge. Flexibility and copolymer formation.

1975 • 81 citations

Regulation of actin-activated ATP hydrolysis by arterial myosin.

1982 • 81 citations

Quantitation of myosin light chain phosphorylation in small tissue samples.

1982 • 74 citations

The apparently negatively cooperative phosphorylation of smooth muscle myosin at low ionic strength is related to its filamentous state.

1983 • 69 citations

Calcium Sensitivity of Contractile Proteins from Chicken Gizzard Muscle1

1978 • 67 citations

Myosin phosphorylation, agonist concentration and contraction of tracheal smooth muscle

1982 • 57 citations

Ca2+, myosin phosphorylation, and relaxation of arterial smooth muscle

1983 • 56 citations

The effect of calcium on the maximum velocity of shortening in skinned skeletal muscle fibres of the rabbit

1982 • 53 citations

Movement of scallop myosin on Nitella actin filaments: regulation by calcium.

1984 • 53 citations

Dependence on Ca2+ and tropomyosin of the actin-activated ATPase activity of phosphorylated gizzard myosin in the presence of low concentrations of Mg2+.

1983 • 33 citations

Tension Transients in Single Isolated Smooth Muscle Cells

1983 • 29 citations