CL 277,082: a novel inhibitor of ACAT-catalyzed cholesterol esterification and cholesterol absorption.

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

The determination of enzyme inhibitor constants

1953 • 4,050 citations

THE SMOOTH MUSCLE CELL

1971 • 1,571 citations

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

1976 • 1,032 citations

The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters.

1980 • 727 citations

Determination of Lecithin: Cholesterol Acyltransfer in Human Blood Plasma

1971 • 559 citations

Rapid Estimation of Free and Total Cholesterol

1954 • 534 citations

Role of acyl-CoA: cholesterol acyltransferase in cellular cholesterol metabolism.

1985 • 519 citations

Cholesterol Ester Metabolism

1965 • 333 citations

Selective inhibition of acyl coenzyme A:cholesterol acyltransferase by compound 58-035.

1984 • 230 citations

Role of acyl CoA:cholesterol acyltransferase in cholesterol absorption and its inhibition by 57-118 in the rabbit.

1983 • 185 citations

Acyl-CoA:cholesterol acyltransferase in human small intestine: its activity and some properties of the enzymic reaction.

1981 • 157 citations

Reduced cholesterol transmucosal transport in rats with inhibited mucosal acyl CoA:cholesterol acyltransferase and normal pancreatic function.

1984 • 118 citations

Influence of Duration of Cholesterol Feeding on Esterification of Fatty Acids by Cell-Free Preparation of Pigeon Aorta

1970 • 115 citations

Effect of dietary fat saturation on acylcoenzyme A:cholesterol acyltransferase activity of rat liver microsomes.

1980 • 114 citations

Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase.

1982 • 103 citations

Stimulation of esterified cholesterol accumulation in tissue culture cells exposed to high density lipoproteins enriched in free cholesterol.

1978 • 92 citations

The role of cholesteryl ester hydrolysis and synthesis in cholesterol transport across rat intestinal mucosal membrane a new concept

1982 • 82 citations

Regulation of Rabbit Intestinal Acyl Coenzyme A-Cholesterol Acyltransferase In Vivo and In Vitro

1982 • 79 citations

Esterification of cholesterol in human small intestine: the importance of acyl‐CoA:cholesterol acyltransferase

1979 • 78 citations

Acyl CoA:retinol acyltransferase in rat small intestine: its activity and some properties of the enzymic reaction.

1982 • 77 citations

Role of Pancreatic Cholesterol Esterase in the Uptake and Esterification of Cholesterol by Isolated Intestinal Cells

1977 • 77 citations

Inhibition of cholesteryl ester formation in human fibroblasts by an analogue of 7-ketocholesterol and by progesterone

1978 • 72 citations

The determination of cholesterol in serum

1952 • 69 citations

Properties of Acyl-coA: cholesterol O-acyltransferase in aortic microsomes from atherosclerotic rabbits

1980 • 67 citations

Properties of a solubilised and reconstituted preparation of ACYL-CoA:cholesterol acyltransferase from rat liver

1982 • 67 citations

Coenzyme-A-Dependent Esterification of Cholesterol in Intestinal Mucosa from Guinea-Pig. Influence of Diet on the Enzyme Activity

1977 • 66 citations

Solubilization, partial purification, and reconstitution in phosphatidylcholine-cholesterol liposomes of acyl-CoA:cholesterol acyltransferase

1982 • 60 citations

Differential effects of isolated lipoproteins from normal and hypercholesterolemic rhesus monkeys on cholesterol esterification and accumulation in arterial smooth muscle cells in culture

1978 • 59 citations

Evidence for phosphorylation/dephosphorylation of rat liver acyl-CoA:cholesterol acyltransferase.

1983 • 58 citations

Dual modulation of hepatic and intestinal acyl‐CoA: cholesterol acyltransferase activity by (de‐)phosphorylation and substrate supply in vitro

1983 • 54 citations

Esterification of cholesterol by homogenates of atherosclerotic and normal aortas

1973 • 52 citations

Cholesterol absorption and transport in thoracic duct lymph lipoproteins of nonhuman primates. Effect of dietary cholesterol level

1983 • 49 citations

15 Acyl Coenzyme A: Cholesterol O-Acyltransferase

1983 • 39 citations

Changes in Lipid Composition of Lymph During Cholesterol Absorption in the Rat

1957 • 36 citations

A defect in mobilization of cholesteryl esters in rabbit macrophages

1985 • 36 citations

Stimulation of Acyl-CoA: Cholesterol Acyltransferase Activity by Hyperlipemic Serum Lipoproteins

1977 • 36 citations

Potential antiatherosclerotic agents. 5. An acyl-coenzyme A:cholesterol O-acyltransferase inhibitor with hypocholesterolemic activity

1986 • 36 citations

The effect of N-(α-methylbenzyl)linoleamide on cholesterol metabolism in rats

1969 • 35 citations

Cholesterol esterification and cholesteryl ester accumulation in cultured pigeon and monkey arterial smooth muscle cells

1979 • 32 citations

Mechanism of the Inhibition of Cholesterol Absorption by DL-Melinamide: Inhibition of Cholesterol Esterification

1986 • 29 citations

Complete hydrolysis of dietary cholesterol esters during intestinal absorption

1965 • 28 citations

Influence of diets on acyl-CoA:cholesterol acyltransferase and on acyl-CoA:retinol acyltransferase in villous and crypt cells from rat small intestinal mucosa and in the liver

1983 • 26 citations

In vitro regulation of bovine adrenal cortical Acyl-CoA:cholesterol acyltransferase and comparison with the rat liver enzyme

1983 • 26 citations

Effect of chlorpromazine on lipid metabolism in aortas from cholesterol-fed rabbits and normal rats, in vitro: Inhibition of sterol esterification and modification of phospholipid synthesis

1983 • 20 citations

The effect of local anesthetics on arterial lipid metabolism

1981 • 19 citations

Regulation of acyl-coA: cholesterol acyltransferase

1983 • 13 citations

The effect of bezafibrate and clofibrate on cholesterol ester metabolism in rabbit peritoneal macrophages stimulated with acetylated low density lipoproteins

1983 • 8 citations

The effect of bezafibrate and clofibrate on cholesterol ester metabolism in 3T3 cells and smooth muscle cells in tissue culture

1982 • 5 citations