Stabilized plasmid-lipid particles: construction and characterization

Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential

1985 • 2,037 citations

A RAPID ALKALINE EXTRACTION PROCEDURE FOR SCREENING RECOMBINANT DNA

1979 • 1,402 citations

Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.

1988 • 1,103 citations

Mechanism of DNA Release from Cationic Liposome/DNA Complexes Used in Cell Transfection^,

1996 • 1,103 citations

The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer

1995 • 779 citations

Improved DNA: liposome complexes for increased systemic delivery and gene expression

1997 • 738 citations

Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside

1981 • 678 citations

In vivo gene transfer via intravenous administration of cationic lipid–protamine–DNA (LPD) complexes

1997 • 470 citations

Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes.

1992 • 454 citations

The polymorphic phase behaviour of phosphatidylethanolamines of natural and synthetic origin. A 31P NMR study

1978 • 416 citations

Introduction of liposome-encapsulated SV40 DNA into cells.

1980 • 407 citations

Systemic gene therapy: biodistribution and long-term expression of a transgene in mice.

1995 • 241 citations

pH-sensitive immunoliposomes mediate target-cell-specific delivery and controlled expression of a foreign gene in mouse.

1987 • 235 citations

Vesicle-micelle transition of phosphatidylcholine and octyl glucoside elucidated by cryo-transmission electron microscopy

1989 • 229 citations

Poly(ethylene glycol)−Lipid Conjugates Regulate the Calcium-Induced Fusion of Liposomes Composed of Phosphatidylethanolamine and Phosphatidylserine

1996 • 204 citations

Recent advances in liposomal drug-delivery systems

1995 • 197 citations

Micelle-vesicle transition of egg phosphatidylcholine and octylglucoside

1988 • 191 citations

Pathways of macromolecular tracer transport across venules and small veins. Structural basis for the hyperpermeability of tumor blood vessels.

1992 • 191 citations

Liposomal Blockade of the Reticuloendothelial System: Improved Tumor Imaging with Small Unilamellar Vesicles

1983 • 182 citations

Comparison of different hydrophobic anchors conjugated to poly(ethylene glycol): effects on the pharmacokinetics of liposomal vincristine

1998 • 163 citations

Entrapment of nucleic acids in liposomes

1997 • 142 citations

Formation of Novel Hydrophobic Complexes between Cationic Lipids and Plasmid DNA

1995 • 113 citations

In vivo gene transfer by intravenous administration of stable cationic lipid/DNA complex.

1997 • 108 citations

Liposomal gene delivery: A complex package

1997 • 105 citations

Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene.

1983 • 100 citations

Entrapment of a bacterial plasmid in phospholipid vesicles: potential for gene transfer.

1979 • 98 citations

Efficient introduction of contents of liposomes into cells using HVJ (Sendai virus)

1985 • 96 citations

Entrapment of plasmid DNA by liposomes and their interactions with plant protoplasts

1979 • 92 citations

Poly(ethylene glycol)−Lipid Conjugates Promote Bilayer Formation in Mixtures of Non-Bilayer-Forming Lipids

1996 • 85 citations

Poly(ethylene glycol)-Modified Phospholipids Prevent Aggregation during Covalent Conjugation of Proteins to Liposomes

1995 • 59 citations

Hexane dissolved in dioleoyllecithin bilayers has a partial molar volume of approximately zero

1985 • 57 citations

Optimization of gene transfer using cationic lipids in cell lines and primary human CD4+ and CD34+ hematopoietic cells.

1995 • 57 citations

Construction of transferrin-coated liposomes for in vivo transport of exogenous DNA to bone marrow erythroblasts in rabbits

1986 • 49 citations

Basic protein enhances the incorporation of DNA into lipid vesicles: model for the formation of primordial cells.

1987 • 49 citations

A New Cationic Liposome Encapsulating Genetic Material

1995 • 48 citations

Liposome-encapsulated DNA-mediated gene transfer and synthesis of human factor IX in mice

1995 • 47 citations

Spermidine-condensed DNA and cone-shaped lipids improve delivery and expression of exogenous DNA transfer by liposomes

1996 • 40 citations

In Vivo Delivery of Human α1-Antitrypsin Gene to Mouse Hepatocytes by Liposomes

1993 • 38 citations

Intracellular fate of liposome-encapsulated DNA in mouse liver. Analysis using electron microscope autoradiography and subcellular fractionation

1985 • 37 citations

THE POLYMORPHIC PHASE BEHAVIOUR OF PHOSPHATIDYLETHANOLAMINES OF NATURAL AND SYNTHETIC ORIGIN

1978 • 36 citations

Expression of A β-lactamase activity in Mycoplasma capricolum transfected with the liposome-encapsulated E. coli pBR 322 plasmid

1982 • 30 citations

Entrapment of high-molecular-mass DNA molecules in liposomes for the genetic transformation of animal cells

1989 • 20 citations

Extraction and Purification of Plasmid DNA

2003 • 16 citations

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