Crystal Structure of the Eosinophil Major Basic Protein at 1.8 Å

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

Two distinct classes of carbohydrate-recognition domains in animal lectins.

1988 • 1,259 citations

ALSCRIPT: a tool to format multiple sequence alignments

1993 • 1,125 citations

The C‐type lectin superfamily in the immune system

1998 • 1,022 citations

Structure of a C-type mannose-binding protein complexed with an oligosaccharide

1992 • 873 citations

Mechanisms of eosinophil-associated inflammation

2000 • 773 citations

Biology of Animal Lectins

1993 • 752 citations

Cytotoxic Properties of the Eosinophil Major Basic Protein

1979 • 595 citations

Structure of the Calcium-Dependent Lectin Domain from a Rat Mannose-Binding Protein Determined by MAD Phasing

1991 • 547 citations

Engineering galactose-binding activity into a C-type mannose-binding protein

1992 • 470 citations

Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

1994 • 397 citations

Damage to Schistosomula of Schistosoma Mansoni Induced Directly by Eosinophil Major Basic Protein

1979 • 368 citations

The Biology of the Eosinophilic Leukocyte

1993 • 345 citations

Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor.

1993 • 332 citations

Activation of basophil and mast cell histamine release by eosinophil granule major basic protein.

1983 • 329 citations

Human eosinophil major basic protein induces airway constriction and airway hyperresponsiveness in primates.

1991 • 310 citations

The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex

1999 • 307 citations

Protein fold recognition using sequence‐derived predictions

1996 • 299 citations

Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand

1999 • 260 citations

Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple α-helical coiled-coil

1994 • 244 citations

Comparative properties of the Charcot-Leyden crystal protein and the major basic protein from human eosinophils.

1976 • 229 citations

Elevated serum levels of the eosinophil granule major basic protein in patients with eosinophilia.

1981 • 213 citations

Human Eosinophil Major Basic Protein Causes Hyperreactivity of Respiratory Smooth Muscle: Role of the Epithelium

1988 • 199 citations

Eosinophil granule proteins in peripheral blood granulocytes

1992 • 183 citations

In vitro killing of microfilariae of Brugia pahangi and Brugia malayi by eosinophil granule proteins.

1990 • 180 citations

Evolving views of protein glycosylation

1998 • 179 citations

Expression of Recombinant Human Pregnancy-associated Plasma Protein-A and Identification of the Proform of Eosinophil Major Basic Protein as Its Physiological Inhibitor

2000 • 174 citations

Localization of human eosinophil granule major basic protein, eosinophil cationic protein, and eosinophil-derived neurotoxin by immunoelectron microscopy.

1986 • 166 citations

Structural Analysis of Monosaccharide Recognition by Rat Liver Mannose-binding Protein

1996 • 165 citations

Crystal structure of the trimeric α-helical coiled-coil and the three lectin domains of human lung surfactant protein D

1999 • 148 citations

PHYSIOCHEMICAL AND BIOLOGICAL PROPERTIES OF THE MAJOR BASIC PROTEIN FROM GUINEA PIG EOSINOPHIL GRANULES

1974 • 142 citations

Acidic precursor revealed in human eosinophil granule major basic protein cDNA.

1988 • 133 citations

Structure of CD94 Reveals a Novel C-Type Lectin Fold

1999 • 127 citations

The Solution Structure of Type II Antifreeze Protein Reveals a New Member of the Lectin Family

1998 • 123 citations

Samter's immunologic diseases

1997 • 119 citations

Eosinophil-fibroblast interactions. Granule major basic protein interacts with IL-1 and transforming growth factor-beta in the stimulation of lung fibroblast IL-6-type cytokine production.

1996 • 115 citations

Comparative Toxicity of Purified Human Eosinophil Granule Proteins for Newborn Larvae of Trichinella spiralis

1987 • 108 citations

The Effect of Purified Human Eosinophil Major Basic Protein on Mammalian Ciliary Activity^1–3

1987 • 103 citations

Noncytotoxic activation of neutrophils by eosinophil granule major basic protein. Effect on superoxide anion generation and lysosomal enzyme release.

1990 • 97 citations

The structure of a tunicate C-type lectin from polyandrocarpa misakiensis complexed with d-galactose

1999 • 94 citations

Mechanism of N-Acetylgalactosamine Binding to a C-type Animal Lectin Carbohydrate-recognition Domain

1998 • 90 citations

Crystal structure of human lithostathine, the pancreatic inhibitor of stone formation.

1996 • 86 citations

Macromolecular Crystal Annealing: Overcoming Increased Mosaicity Associated with Cryocrystallography

1998 • 86 citations

Crystal Structure of the C-type Lectin-like Domain from the Human Hematopoietic Cell Receptor CD69

2001 • 81 citations

Interaction of eosinophil granule major basic protein with synthetic lipid bilayers: A mechanism for toxicity

1992 • 79 citations

Effect of Human Eosinophil Major Basic Protein on Ion Transport in Dog Tracheal Epithelium

1988 • 79 citations

Acidic polyamino acids inhibit human eosinophil granule major basic protein toxicity. Evidence of a functional role for ProMBP.

1991 • 76 citations

Regulation and Processing of a Precursor Form of Eosinophil Granule Major Basic Protein (ProMBP) in Differentiating Eosinophils

1998 • 73 citations

A Novel and Highly Divergent Homolog of Human Eosinophil Granule Major Basic Protein

1999 • 72 citations

Crystal Structure of Human CD69: A C-Type Lectin-Like Activation Marker of Hematopoietic Cells^,

2000 • 68 citations

Isolation of a complementary DNA clone encoding a precursor to human eosinophil major basic protein.

1988 • 54 citations

Recognition of complex carbohydrates by Ca2+-dependent animal lectins

1993 • 51 citations

Eosinophil activation and function in health and disease.

1992 • 38 citations

Location and nature of carbohydrate groups in proform of human major basic protein isolated from pregnancy serum.

1994 • 31 citations

Expression, purification, and characterization of the recombinant proform of eosinophil granule major basic protein.

1995 • 29 citations

Localization of disulfide bridges and free sulfhydryl groups in human eosinophil granule major basic protein

1994 • 20 citations

Homology of cytotoxic protein of eosinophilic leukocytes with IgE receptor Fcϵ RII: Implications for its structure and function

1989 • 11 citations