Placental Glutathione S-Transferase (GST-P) as a New Marker for Hepatocarcinogenesis: In Vivo Short-Term Screening for Hepatocarcinogens

THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE

1966 • 6,585 citations

The Isoenzymes of Glutathione Transferase

1985 • 960 citations

Purification, induction, and distribution of placental glutathione transferase: a new marker enzyme for preneoplastic cells in the rat chemical hepatocarcinogenesis.

1985 • 501 citations

Reduction and enhancement by phenobarbital of hepatocarcinogenesis induced in the rat by 2-acetylaminofluorene.

1971 • 412 citations

Cellular biochemistry of the stepwise development of cancer with chemicals: G. H. A. Clowes memorial lecture.

1984 • 363 citations

The placental form of glutathione S-transferase as a new marker protein for preneoplasia in rat chemical hepatocarcinogenesis.

1984 • 336 citations

Efficacy and Specificity of Chenodeoxycholic Acid Therapy for Dissolving Gallstones

1973 • 287 citations

Promoting activities of butylated hydroxyanisole and butylated hydroxytoluene on 2-stage urinary bladder carcinogenesis and inhibition of γ-glutamyl transpeptidase-positive foci development in the liver of rats

1983 • 272 citations

Chemical characterization of 465 known or suspected carcinogens and their correlation with mutagenic activity in the Salmonella typhimurium system.

1979 • 267 citations

Induction of resistant hepatocytes as a new principle for a possible short-term in vivo test for carcinogens.

1980 • 243 citations

The first relevant cell stage in rat liver carcinogenesis a quantitative approach

1980 • 235 citations

Relative merits of immunohistochemical demonstrations of placental, A, B and C forms of glutathione S-transferase and histochemical demonstration of γ-glutamyl transferase as markers of altered foci during liver carcinogenesis in rats

1985 • 231 citations

Glutathione transferases: Nomenclature

1984 • 231 citations

Fundamentals of Cancer Prevention

2013 • 222 citations

Hepatocellular glycogenosis and hepatocarcinogenesis

1980 • 205 citations

Phenotypic diversity as an early property of putative preneoplastic hepatocyte populations in liver carcinogenesis.

1980 • 203 citations

Redifferentiation as a basis for remodeling of carcinogen-induced hepatocyte nodules to normal appearing liver.

1983 • 194 citations

The effects of various chemicals on the development of hyperplastic liver nodules in hepatectomized rats treated with N-nitrosodiethylamine or N-2-fluorenylacetamide.

1980 • 103 citations

Comparative Effects of Carcinogens on the Induction of Placental Glutathione S-Transferase-positive Liver Nodules in a Short-term Assay and of Hepatocellular Carcinomas in a Long-term Assay

1985 • 96 citations

Survey of various chemicals for initiating and promoting activities in a short-term in vivo system based on generation of hyperplastic liver nodules in rats

1983 • 78 citations

Enhancing effect of phenobarbital on the development of enzyme-altered islands and hepatocellular carcinomas initiated by 3'-methyl-4-(dimethylamino) azobenzene or diethylnitrosamine.

1978 • 77 citations

7,12-Dimethylbenz(α)anthracene and hepatic neoplasia in regenerating rat liver

1970 • 65 citations

Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea.

1983 • 64 citations

Promoting effect of sodium o-phenylphenate and o-phenylphenol on two-stage urinary bladder carcinogenesis in rats.

1983 • 56 citations

Rapid production of hyperplastic liver nodules in rats treated with carcinogenic chemicals: a new approach for an in vivo short-term screening test for hepatocarcinogens.

1977 • 52 citations

Modifying potential of thirty-one chemicals on the short-term development of gamma-glutamyl transpeptidase-positive foci in diethylnitrosamine-initiated rat liver.

1984 • 50 citations

Hepatotoxicity of bile acids in rabbits: ursodeoxycholic acid is less toxic than chenodeoxycholic acid.

1982 • 46 citations

Dose-dependent effects of butylated hydroxyanisole, butylated hydroxytoluene and ethoxyquin in induction of foci of rat liver cells containing the placental form of glutathione S-transferase

1985 • 34 citations

Carcinogenicities of quinoline derivatives in F344 rats

1981 • 25 citations

Development of hepatomas in inbred albino mice following treatment with 20-methylcholanthrene.

1959 • 25 citations

Modification of chemical carcinogenesis by antioxidants.

1983 • 20 citations

Dose and sex dependent effects of 2-acetylamino-fluorene, 3′-methyl-4-dimethylaminoazobenzene and dl-ethionine in induction of γ-glutamyl transpeptidase-positive liver cell foci in rats

1983 • 19 citations

Inhibitory potential of acetaminophen and o-, m-, p-aminophenols for development of γ-glutamyltranspeptidase-positive liver cell foci in rats pretreated with diethylnitrosamine

1985 • 18 citations

Markers of Liver Neoplasia — Real or Fictional?

1983 • 15 citations

Carcinogenicity of Dipyrone in (C57BL/6 × C3H)F₁ Mice<xref ref-type="fn" rid="FN2">2</xref>

1983 • 15 citations

Elevation of gamma-glutamyl transpeptidase activity in rat liver induced by feeding of butylated hydroxytoluene.

1983 • 8 citations

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